2025
Efficacy of cannabinoids for the prophylaxis of chemotherapy-induced nausea and vomiting—a systematic review and meta-analysis
Chow R, Basu A, Kaur J, Hui D, Im J, Prsic E, Boldt G, Lock M, Eng L, Ng T, Zimmermann C, Scotte F. Efficacy of cannabinoids for the prophylaxis of chemotherapy-induced nausea and vomiting—a systematic review and meta-analysis. Supportive Care In Cancer 2025, 33: 193. PMID: 39953210, PMCID: PMC11828838, DOI: 10.1007/s00520-025-09251-w.Peer-Reviewed Original ResearchConceptsChemotherapy-induced nausea and vomitingEfficacy of cannabinoidsTHC:CBDMeta-analysisPrevention of chemotherapy-induced nausea and vomitingProphylaxis of chemotherapy-induced nausea and vomitingChemotherapy-induced nausea and vomiting controlControlled TrialsCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsRegister of Controlled TrialsNausea and vomitingChemotherapy-induced nauseaMethodsA literature searchCochrane Central RegisterComplete responseRandomized Controlled TrialsNo vomitingAdjunctive therapyRescue medicationAntiemetic regimensComposite endpointSubgroup analysisCannabinoidSecondary prevention
2024
Assessment of the productivity loss due to leading maternal ill-health conditions: a follow-up study of a prospective pregnancy cohort in rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Assessment of the productivity loss due to leading maternal ill-health conditions: a follow-up study of a prospective pregnancy cohort in rural Sri Lanka. BMJ Open 2024, 14: e082798. PMID: 39477261, DOI: 10.1136/bmjopen-2023-082798.Peer-Reviewed Original ResearchConceptsIll-health conditionsRural Sri LankaPregnant womenPregnancy cohortFollow-up study of womenFollow-up studyProspective pregnancy cohortRajarata Pregnancy CohortSecondary outcome measuresMonthly household expenditureVaginal bleedingProductivity lossStudy of womenPrimary outcome measurePregnancy follow-upMedical careOutcome measuresHigher absenteeismNausea and vomitingPresenteeismHighest prevalenceAbsenteeismThird trimesterWomenRecommended prioritiesMulti-day vs single-day dexamethasone for the prophylaxis of chemotherapy-induced nausea and vomiting: systematic review and meta-analysis
Chow R, Celio L, Im J, Caini S, Eng L, Prsic E, Scotté F, Aapro M. Multi-day vs single-day dexamethasone for the prophylaxis of chemotherapy-induced nausea and vomiting: systematic review and meta-analysis. Supportive Care In Cancer 2024, 32: 736. PMID: 39432169, DOI: 10.1007/s00520-024-08934-0.Peer-Reviewed Original ResearchConceptsDexamethasone-sparing regimenChemotherapy-induced nausea and vomitingModerately emetogenic chemotherapyHighly emetogenic chemotherapyRandomized Controlled TrialsComplete responseMeta-analysisEmetogenic chemotherapyNo vomitingRescue medicationProphylaxis of chemotherapy-induced nausea and vomitingSystematic reviewSchedule of dexamethasoneNausea and vomitingChemotherapy-induced nauseaResultsTen trialsAntiemetic regimenCumulative meta-analysisEffect estimatesSafety profileComprehensive systematic reviewMethodsOvid MEDLINERegimensAdult cancer patientsCancer patients
2023
Clinical experience with the use of inhaled isopropyl alcohol to treat nausea and vomiting: A narrative review.
Amaya S, Kalsotra S, Tobias J, Olbrecht V. Clinical experience with the use of inhaled isopropyl alcohol to treat nausea and vomiting: A narrative review. Saudi Journal Of Anaesthesia 2023, 17: 383-390. PMID: 37601520, PMCID: PMC10435785, DOI: 10.4103/sja.sja_151_23.Peer-Reviewed Original ResearchInhaled isopropyl alcoholNausea and vomitingTreatment of PONVPerioperative settingAntiemetic agentsOperating roomManagement of nausea and vomitingTreat nausea and vomitingTreatment of postoperative nauseaRisk of adverse effectsLow risk of adverse effectsSeverity of PONVShort-term treatmentNarrative reviewAdverse effectsEmergency department settingAction of IAMechanism of actionAdult patientsTreat PONVAntiemetic effectPostoperative nauseaClinical trialsClinical effectsInexpensive therapy
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