2015
Effect of Ischemia Duration and Door-to-Balloon Time on Myocardial Perfusion in ST-Segment Elevation Myocardial Infarction An Analysis From HORIZONS-AMI Trial (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction)
Prasad A, Gersh BJ, Mehran R, Brodie BR, Brener SJ, Dizon JM, Lansky AJ, Witzenbichler B, Kornowski R, Guagliumi G, Dudek D, Stone GW. Effect of Ischemia Duration and Door-to-Balloon Time on Myocardial Perfusion in ST-Segment Elevation Myocardial Infarction An Analysis From HORIZONS-AMI Trial (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction). JACC Cardiovascular Interventions 2015, 8: 1966-1974. PMID: 26738667, DOI: 10.1016/j.jcin.2015.08.031.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCoronary CirculationDrug-Eluting StentsFemaleHumansMaleMetalsMicrocirculationMiddle AgedMyocardial InfarctionMyocardial Perfusion ImagingPercutaneous Coronary InterventionProspective StudiesProsthesis DesignRisk AssessmentRisk FactorsStentsTime FactorsTime-to-TreatmentTreatment OutcomeConceptsPrimary percutaneous coronary interventionMyocardial blush gradePrimary PCIHORIZONS-AMI trialMBG 0/1Balloon timeIndependent predictorsAnterior infarctionMyocardial perfusionST-segment elevation myocardial infarction (STEMI) patientsST-segment elevation myocardial infarctionHigher clinical risk profileElevation myocardial infarction patientsMyocardial Infarction (TIMI) risk scoreClinical risk profileMechanical reperfusion therapyReference vessel diameterElevation myocardial infarctionPercutaneous coronary interventionST-segment elevationEpicardial blood flowMinimum lumen diameterMyocardial infarction patientsMicrovascular reperfusionBlush gradePhysicians' perceptions of the Thrombolysis in Myocardial Infarction (TIMI) risk score in older adults with acute myocardial infarction
Feder SL, Schulman-Green D, Geda M, Williams K, Dodson JA, Nanna MG, Allore HG, Murphy TE, Tinetti ME, Gill TM, Chaudhry SI. Physicians' perceptions of the Thrombolysis in Myocardial Infarction (TIMI) risk score in older adults with acute myocardial infarction. Heart & Lung 2015, 44: 376-381. PMID: 26164651, PMCID: PMC4567390, DOI: 10.1016/j.hrtlng.2015.05.005.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial Infarction (TIMI) risk scoreRisk scoreOlder adultsMyocardial infarctionMedian sample ageTIMI risk scoreRisk stratification modelSemi-structured telephone interviewsRisk factorsNew risk modelAMI treatmentPhysicians' perceptionsMortality riskClinical experienceClinical practiceStratification modelTelephone interviewsAdultsThrombolysisInfarctionConstant comparative methodPhysiciansScoresQualitative study
2009
Choice of Reperfusion Strategy at Hospitals With Primary Percutaneous Coronary Intervention
Fazel R, Krumholz HM, Bates ER, French WJ, Frederick PD, Nallamothu BK. Choice of Reperfusion Strategy at Hospitals With Primary Percutaneous Coronary Intervention. Circulation 2009, 120: 2455-2461. PMID: 19948977, DOI: 10.1161/circulationaha.109.860544.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionPCI-capable hospitalsPrimary PCIReperfusion strategyMyocardial infarctionFibrinolytic therapySystem-related factorsPercutaneous coronary intervention capabilityMyocardial Infarction (TIMI) risk scorePrimary percutaneous coronary interventionHierarchical multivariable logistic regressionKey clinical factorsPercutaneous coronary interventionMultivariable logistic regressionPCI useCardiogenic shockCoronary interventionClinical factorsIntracranial hemorrhageNonwhite raceNational registryRisk factorsAdvanced ageFemale gender
2005
Performance of the Thrombolysis in Myocardial Infarction (TIMI) ST-elevation myocardial infarction risk score in a national cohort of elderly patients
Rathore SS, Weinfurt KP, Foody JM, Krumholz HM. Performance of the Thrombolysis in Myocardial Infarction (TIMI) ST-elevation myocardial infarction risk score in a national cohort of elderly patients. American Heart Journal 2005, 150: 402-410. PMID: 16169316, PMCID: PMC2790534, DOI: 10.1016/j.ahj.2005.03.069.Peer-Reviewed Original ResearchConceptsThirty-day mortality rateTIMI scoreElderly patientsMortality rateRisk scoreMyocardial Infarction (TIMI) risk scoreHigh TIMI scoreMyocardial Infarction (TIMI) scoreCommunity-based cohortReperfusion therapyTrial cohortPrognostic discriminationTrial populationNational cohortModest discriminationPatientsUS hospitalsSTEMICohortScore discriminationScoresThrombolysis
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