Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing
Zheng J, Sadot E, Vigidal J, Klimstra D, Balachandran V, Kingham T, Allen P, D’Angelica M, DeMatteo R, Jarnagin W, Ventura A. Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing. PLOS ONE 2018, 13: e0200776. PMID: 30052636, PMCID: PMC6063411, DOI: 10.1371/journal.pone.0200776.Peer-Reviewed Original ResearchMeSH KeywordsAdenoma, Liver CellAdultAgedAged, 80 and overbeta CateninBiomarkers, TumorCarcinoma, HepatocellularCluster AnalysisDNA Mutational AnalysisFemaleGene Expression Regulation, NeoplasticHumansImmunohistochemistryInflammationLiver NeoplasmsMaleMicroRNAsMiddle AgedPilot ProjectsSequence Analysis, DNASequence Analysis, RNAConceptsMiR-490-3pMiR-520c-3pMiR-515-5pMicroRNA profilesMiR-490MiR-515MiR-1180MiR-766MiR-429MiR-518bMiR-200aMiR-452MiR-517aDrivers of hepatocarcinogenesisMiRNA clusterMicroRNAsMicroRNA expressionHepatocellular adenomaHepatocellular carcinomaMiRNAsNon-neoplastic liverTargeted gene sequencingNormal liverBenign liver tumorsNon-tumor liver tissues
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