2018
Systematic review of the real‐world evidence of adalimumab safety in psoriasis registries
Strober B, Crowley J, Langley R, Gordon K, Menter A, Leonardi C, Arikan D, Valdecantos W. Systematic review of the real‐world evidence of adalimumab safety in psoriasis registries. Journal Of The European Academy Of Dermatology And Venereology 2018, 32: 2126-2133. PMID: 30067882, DOI: 10.1111/jdv.15203.Peer-Reviewed Original ResearchConceptsMajor cardiac eventsAdverse eventsPsoriasis RegistryReal-world evidenceAdalimumab safetySerious AEsAdult patientsCardiac eventsClinical studiesSafety dataLong-term safety profileCardiovascular-related eventsSerious adverse eventsSerious cardiovascular eventsReal-world safetyLong-term safetyRate of infectionEnglish language manuscriptsCardiovascular eventsSafety profileSerious infectionsAdalimumabClinical practiceEligible papersRegistry
2017
Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From the American College of Physicians and the American Academy of Family Physicians.
Qaseem A, Wilt T, Rich R, Humphrey L, Frost J, Forciea M, Fitterman N, Barry M, Horwitch C, Iorio A, McLean R. Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From the American College of Physicians and the American Academy of Family Physicians. Annals Of Internal Medicine 2017, 166: 430-437. PMID: 28135725, DOI: 10.7326/m16-1785.Peer-Reviewed Original ResearchConceptsSpecific blood pressure targetsBlood pressure targetsTarget systolic blood pressureSystolic blood pressureLower blood pressure targetsPressure targetsBlood pressureCardiac eventsPharmacologic treatmentTreatment goalsPatient populationAmerican CollegeFamily physiciansAmerican AcademyAdults Aged 60 YearsHigh cardiovascular riskTransient ischemic attackMajor cardiac eventsHistory of strokeClinical practice guidelinesTreatment of hypertensionTarget patient populationIschemic attackRecurrent strokeCause mortality
2014
Effect of &bgr;-Blockers on Cardiac and Pulmonary Events and Death in Older Adults With Cardiovascular Disease and Chronic Obstructive Pulmonary Disease
Lee DS, Markwardt S, McAvay GJ, Gross CP, Goeres LM, Han L, Peduzzi P, Lin H, Dodson JA, Tinetti ME. Effect of &bgr;-Blockers on Cardiac and Pulmonary Events and Death in Older Adults With Cardiovascular Disease and Chronic Obstructive Pulmonary Disease. Medical Care 2014, 52: s45-s51. PMID: 24561758, PMCID: PMC4050644, DOI: 10.1097/mlr.0000000000000035.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseΒ-blocker useMajor cardiac eventsObstructive pulmonary diseasePulmonary eventsCardiovascular diseaseCardiac eventsOlder adultsPulmonary diseaseΒ-blockersCOPD/asthmaMajor pulmonary eventsCox proportional hazardsPulmonary outcomesCause mortalityHazard ratioStudy criteriaMedicare beneficiariesProportional hazardsSurvey cohortDiseaseAdultsMedicationsOutcomesDeath
2011
Impact of baseline thrombocytopenia on the early and late outcomes after ST-elevation myocardial infarction treated with primary angioplasty: Analysis from the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial
Hakim DA, Dangas GD, Caixeta A, Nikolsky E, Lansky AJ, Moses JW, Claessen B, Sanidas E, White HD, Ohman EM, Manoukian SV, Fahy M, Mehran R, Stone GW. Impact of baseline thrombocytopenia on the early and late outcomes after ST-elevation myocardial infarction treated with primary angioplasty: Analysis from the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial. American Heart Journal 2011, 161: 391-396. PMID: 21315224, DOI: 10.1016/j.ahj.2010.11.001.Peer-Reviewed Original ResearchConceptsST-elevation myocardial infarctionPrimary percutaneous coronary interventionBaseline thrombocytopeniaMajor cardiac eventsPercutaneous coronary interventionMyocardial infarctionMajor bleedingPrimary angioplastyCardiac eventsCoronary interventionLate outcomesNet adverse clinical eventsAcute Myocardial Infarction trialHORIZONS-AMI trialMajor cardiovascular eventsMyocardial Infarction trialOutcomes of patientsAcute coronary syndromeAdverse clinical eventsEarly adverse eventsAcute myocardial infarctionHarmonizing OutcomesCardiovascular eventsCoronary syndromeAdverse events
2006
Coronary stenting is safe and effective in a high-risk octogenarian patient cohort.
Baklanov DV, Marcu CB, Juhasz DF, Caracciolo EA, Chawarski MC, Donohue TJ. Coronary stenting is safe and effective in a high-risk octogenarian patient cohort. Connecticut Medicine 2006, 70: 15-9. PMID: 16479871.Peer-Reviewed Original ResearchConceptsTarget vessel revascularization rateCoronary stentingProcedural successNew York Heart Association class IIIHigh procedural success rateSerial cardiac enzymesVessel revascularization ratePercent of patientsTIMI 3 flowAcute coronary syndromeMajor cardiac eventsProcedural success rateLow complication rateCoronary heart diseaseCommunity teaching hospitalHigh-risk populationLong-term resultsCoronary stent proceduresAngiographic profileCoronary syndromeIndex hospitalizationRevascularization ratesCardiac eventsComplication rateResidual stenosis
2000
Intracoronary γ-Radiation Therapy After Angioplasty Inhibits Recurrence in Patients With In-Stent Restenosis
Waksman R, White R, Chan R, Bass B, Geirlach L, Mintz G, Satler L, Mehran R, Serruys P, Lansky A, Fitzgerald P, Bhargava B, Kent K, Pichard A, Leon M. Intracoronary γ-Radiation Therapy After Angioplasty Inhibits Recurrence in Patients With In-Stent Restenosis. Circulation 2000, 101: 2165-2171. PMID: 10801757, DOI: 10.1161/01.cir.101.18.2165.Peer-Reviewed Original ResearchConceptsStent restenosisIntracoronary gamma radiation therapyLess target lesion revascularizationBinary angiographic restenosisSuccessful coronary interventionTarget lesion revascularizationMajor cardiac eventsIndependent core laboratoryIntracoronary stent implantationInitial clinical trialsGamma radiation therapyLesion revascularizationAngiographic restenosisVessel revascularizationAngiographic outcomesCardiac eventsClinical restenosisCoronary interventionAdjunct therapyProcedural successStent implantationClinical trialsTreatment protocolNeointimal formationRadiation group
1999
Procedural and late outcomes following MULTI-LINK DUET coronary stent deployment
Kereiakes D, Midei M, Hermiller J, O’Shaughnessy C, Schlofmitz R, Yakubov S, Fink S, Hu F, Nishimura N, Sievers M, Valentine M, Broderick T, Lansky A, Moses J. Procedural and late outcomes following MULTI-LINK DUET coronary stent deployment. The American Journal Of Cardiology 1999, 84: 1385-1390. PMID: 10606109, DOI: 10.1016/s0002-9149(99)00581-0.Peer-Reviewed Original ResearchConceptsPrimary end pointMinimal lumen diameterMulti-Link stentComposite primary end pointPostprocedural minimal lumen diameterLumen diameterEnd pointMajor cardiac eventsProspective multicenter registryQuantitative coronary angiographyCoronary stent deploymentMultivariate regression modelingAngiographic restenosisMulticenter registryAngiographic outcomesCardiac eventsCurrent smokingCoronary angiographyDiabetes mellitusIndependent predictorsLesion eccentricityProcedural successTarget stenosisStent lengthLate outcomes
1997
Stent Placement Compared with Balloon Angioplasty for Obstructed Coronary Bypass Grafts
Savage M, Douglas J, Fischman D, Pepine C, King S, Werner J, Bailey S, Overlie P, Fenton S, Brinker J, Leon M, Goldberg S, Heuser R, Smalling R, Safian R, Cleman M, Buchbinder M, Snead D, Rake R, Gebhardt S. Stent Placement Compared with Balloon Angioplasty for Obstructed Coronary Bypass Grafts. New England Journal Of Medicine 1997, 337: 740-747. PMID: 9287229, DOI: 10.1056/nejm199709113371103.Peer-Reviewed Original ResearchConceptsSaphenous vein graftsBalloon angioplastyStent groupLuminal diameterBypass surgeryBypass graftStent placementAortocoronary venous bypass graftsCoronary artery bypass surgeryBypass graft lesionsMajor cardiac complicationsStandard balloon angioplastyPrimary end pointMajor cardiac eventsCoronary bypass graftsTreatment of stenosisPalmaz-Schatz stentsLargest mean increaseAngioplasty groupAngiographic restenosisCardiac complicationsHemorrhagic complicationsAngiographic outcomesCardiac eventsCoronary angiography
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