2005
Antineural antibody in patients with Tourette’s syndrome and their family members
Yeh CB, Wu CH, Tsung HC, Chen CW, Shyu JF, Leckman JF. Antineural antibody in patients with Tourette’s syndrome and their family members. Journal Of Biomedical Science 2005, 13: 101-112. PMID: 16215701, DOI: 10.1007/s11373-005-9033-y.Peer-Reviewed Original ResearchConceptsAntineural antibodiesTourette syndromeTS patientsTic disordersControl groupFirst-degree family membersAge-matched control groupFamily membersSera of controlsImmunological pathophysiologyStreptococcal infectionPrimary cell culturesPatientsInfectious agentsSyndromeNeuropsychiatric disordersWestern blottingAntibodiesRat tissuesInteraction of geneticsGenetic vulnerabilitySerumDisordersFuture studiesCell cultures
2001
Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders
Morshed S, Parveen S, Leckman J, Mercadante M, Kiss M, Miguel E, Arman A, Yazgan Y, Fujii T, Paul S, Peterson B, Zhang H, King R, Scahill L, Lombroso P. Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders. Biological Psychiatry 2001, 50: 566-577. PMID: 11690591, DOI: 10.1016/s0006-3223(01)01096-4.Peer-Reviewed Original ResearchConceptsTotal antinuclear antibodiesAntinuclear antibodiesAutoimmune disordersTourette syndromeAnticytoskeletal antibodiesAntineural antibodiesStreptococcal infectionT patientsTS patientsBeta-hemolytic streptococcal infectionPrior streptococcal infectionHemolytic streptococcal infectionAntistreptolysin O titerIndirect immunofluorescent assayLevels of immunoreactivityWestern blot techniqueMean rankClinical characteristicsSydenham's choreaO titerPatient groupSC patientsIgG antibodiesIgG classNormal controls
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