2022
Characterization of hearing-impairment in Generalized Arterial Calcification of Infancy (GACI)
Theng EH, Brewer CC, Oheim R, Zalewski CK, King KA, Delsmann MM, Rolvien T, Gafni RI, Braddock DT, Jeffrey Kim H, Ferreira CR. Characterization of hearing-impairment in Generalized Arterial Calcification of Infancy (GACI). Orphanet Journal Of Rare Diseases 2022, 17: 273. PMID: 35854274, PMCID: PMC9295326, DOI: 10.1186/s13023-022-02410-w.Peer-Reviewed Original ResearchConceptsOssicular chain dysfunctionGeneralized Arterial CalcificationOtitis mediaArterial calcificationPrevalence of HLRecurrent otitis mediaTerms of patientTemporal bone imagingEtiology of HLBasic science laboratoryAuricular calcificationConductive HLHL etiologyOtologic featuresDegree of HLCohort studyOtologic evaluationRadiologic featuresAudiological assessmentAuditory dysfunctionTube placementRecurrent episodesBilateral HLCranial CTLikely multifactorial
2021
Symptomatic Responses to Low‐Level Occupational and Environmental Exposures
Linde B, Redlich C. Symptomatic Responses to Low‐Level Occupational and Environmental Exposures. 2021, 1-14. DOI: 10.1002/0471435139.hyg013.pub3.ChaptersLow-level exposureSymptomatic responseManagement of symptomsMultiple chemical sensitivityIdiopathic environmental intoleranceLikely multifactorialMedical evaluationPatient's conditionChemical intoleranceGasoline fumesEnvironmental intoleranceDiagnostic termsSymptomsEnvironmental exposuresPerfumed productsWork accommodationsNew carpetingExposureIntolerancePsychological pathwaysChemical sensitivityResponsePathogenesisMultifactorialDiagnosis
2014
Epstein–Barr Virus: Epidemiology and Clinical Features of Related Cancer
Hudnall S. Epstein–Barr Virus: Epidemiology and Clinical Features of Related Cancer. 2014, 25-50. DOI: 10.1007/978-1-4939-0870-7_3.Peer-Reviewed Original ResearchCell lymphomaEBV latency genesRisk of EBVEBV-positive lymphomasNK-cell lymphomasEpstein-Barr virusEndemic Burkitt lymphomaEBV gene expressionB-cell lymphomaHuman malignant tumorsImmunodeficiency-associated lymphomasApparent immunodeficiencyEBV infectionFalciparum malariaLymphoepithelial carcinomaOrgan failureClinical featuresImmunocompetent hostsLikely multifactorialSeroprevalence ratesImmunodeficient hostsMalignant tumorsSevere diseaseNasopharyngeal carcinomaBurkitt's lymphoma
2013
A 7-year-old boy with renal insufficiency and proteinuria after stem cell transplant for T-cell acute lymphoblastic leukemia
Goodwin JE, Palmer M, Pashankar F, Tufro A, Moeckel G. A 7-year-old boy with renal insufficiency and proteinuria after stem cell transplant for T-cell acute lymphoblastic leukemia. Clinical Nephrology 2013, 82: 205-210. PMID: 23391318, PMCID: PMC6990651, DOI: 10.5414/cn107767.Peer-Reviewed Original ResearchConceptsStem cell transplantHematopoietic stem cell transplantCell transplantRenal insufficiencyKidney biopsyPediatric patientsNephrotic syndromeExtensive foot process effacementAbnormal lymphocyte responsesT-cell acute lymphoblastic leukemiaChronic kidney diseaseChronic interstitial nephritisAcute lymphoblastic leukemiaPre-conditioning regimensFoot process effacementHost diseaseImmunosuppressive therapyRenal failureInterstitial nephritisLymphocyte responsesCommon sequelaeInterstitial infiltratesProphylactic medicationKidney diseaseLikely multifactorial
2011
Endometriosis: Pathogenesis and Management of Pain
Kulp J, Arici A. Endometriosis: Pathogenesis and Management of Pain. 2011, 40-49. DOI: 10.1002/9781444391855.ch4.Peer-Reviewed Original ResearchNonsteroidal anti-inflammatory medicationsGonadotropin-releasing hormone agonistAnti-inflammatory medicationsChronic pelvic painDysfunctional immune responseManagement of painOral contraceptive pillsSymptoms of endometriosisTime of laparoscopyEtiology of endometriosisSymptomatic endometriomasPelvic painSurgical treatmentHormone agonistMedical managementRetrograde menstruationContraceptive pillsLikely multifactorialImmune responseCommon conditionEndometriosisGenetic predispositionPainStem cellsPopulation of lesions
2008
Pacemaker Therapy for Early and Late Sinus Node Dysfunction in Orthotopic Heart Transplant Recipients: A Single‐Center Experience
LUEBBERT JJ, LEE FA, ROSENFELD LE. Pacemaker Therapy for Early and Late Sinus Node Dysfunction in Orthotopic Heart Transplant Recipients: A Single‐Center Experience. Pacing And Clinical Electrophysiology 2008, 31: 1108-1112. PMID: 18834460, DOI: 10.1111/j.1540-8159.2008.01149.x.Peer-Reviewed Original ResearchConceptsOrthotopic heart transplantationSinus node dysfunctionOHT recipientsEarly complicationsTransplant recipientsLate sinus node dysfunctionSignificant sinus node dysfunctionOrthotopic heart transplant recipientsHeart transplant clinicMean age 50.2Heart transplant recipientsSingle-center experienceAge 50.2Electrophysiology serviceTransplant clinicHeart transplantationHeart transplantPermanent pacemakerLikely multifactorialPacemaker therapyLarge cohortPatientsAmbulatory monitoringRecipientsPacemakerMatrix Metalloproteinase 9 Facilitates West Nile Virus Entry into the Brain
Wang P, Dai J, Bai F, Kong KF, Wong SJ, Montgomery RR, Madri JA, Fikrig E. Matrix Metalloproteinase 9 Facilitates West Nile Virus Entry into the Brain. Journal Of Virology 2008, 82: 8978-8985. PMID: 18632868, PMCID: PMC2546894, DOI: 10.1128/jvi.00314-08.Peer-Reviewed Original ResearchConceptsMatrix metalloproteinase-9Blood-brain barrierWest Nile virusWNV entryMetalloproteinase-9MMP9 expressionWNV infectionIntact blood-brain barrierBlood-brain barrier permeabilityBrain viral loadWest Nile virus entryEvans blue leakageMosquito-borne encephalitisWest Nile encephalitisLethal WNV challengeWild-type miceCentral nervous systemType IV collagen degradationPeripheral viremiaViral loadLeukocyte infiltrateInflammatory cytokinesLikely multifactorialBarrier permeabilityHost cytokinesStem Cells and the Pathogenesis of Endometriosis
Sasson IE, Taylor HS. Stem Cells and the Pathogenesis of Endometriosis. Annals Of The New York Academy Of Sciences 2008, 1127: 106-115. PMID: 18443337, PMCID: PMC3107843, DOI: 10.1196/annals.1434.014.Peer-Reviewed Original ResearchConceptsPathogenesis of endometriosisGynecological disordersEndometrial stem/progenitor cellsChronic pelvic painCommon gynecological disorderEndometrial stem cellsStem/progenitor cellsStem cellsPelvic painEndometrial tissueUterine cavityLikely multifactorialExtensive morbidityMenstrual cycleEndometriosisRole of geneticsImmune systemNarrative reviewPathogenesisProgenitor cellsPotential roleImportant unanswered questionsSuch cellsDisordersCellsMultidimensional System Biology: Genetic Markers and Proteomic Biomarkers of Adverse Pregnancy Outcome in Preterm Birth
Buhimschi C, Rosenberg V, Dulay A, Thung S, Sfakianaki A, Bahtiyar M, Buhimschi I. Multidimensional System Biology: Genetic Markers and Proteomic Biomarkers of Adverse Pregnancy Outcome in Preterm Birth. American Journal Of Perinatology 2008, 25: 175-187. PMID: 18425720, DOI: 10.1055/s-2008-1061497.Peer-Reviewed Original ResearchConceptsPreterm birthSignificant public health problemMost preterm birthsAdverse pregnancy outcomesWeeks of gestationPublic health problemVariety of interventionsNeonatal outcomesPregnancy outcomesDecidual hemorrhagePremature infantsPremature birthLikely multifactorialPathophysiological pathwaysHealth problemsPathophysiological conditionsProteomic biomarkersOxidative stressBirthExcessive stretchingOutcomesHemorrhageGestationInfantsEtiology
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