1992
Thyrotropin-releasing hormone-mediated Mn2+ entry in perifused rat anterior pituitary cells
Cui Z, Dannies P. Thyrotropin-releasing hormone-mediated Mn2+ entry in perifused rat anterior pituitary cells. Biochemical Journal 1992, 283: 507-513. PMID: 1575695, PMCID: PMC1131064, DOI: 10.1042/bj2830507.Peer-Reviewed Original ResearchConceptsAnterior pituitary cellsRat anterior pituitary cellsPituitary cellsMicroM dopaminePerifused anterior pituitary cellsIndo-1-loaded cellsReceptor-mediated Ca2Action of TRHContinuous TRH infusionTRH infusionCation entryIntracellular Ca2Indo-1TRHTumor promotorFree mediumG proteinsUnstimulated cellsCell typesDopamineCa2CellsLittle effectInsensitive wavelengthInfusion
1989
The effect of recombinant erythropoietin on intracellular free calcium in erythropoietin-responsive cells.
Imagawa S, Smith B, Palmer-Crocker R, Bunn H. The effect of recombinant erythropoietin on intracellular free calcium in erythropoietin-responsive cells. Blood 1989, 73: 1452-7. PMID: 2496770, DOI: 10.1182/blood.v73.6.1452.bloodjournal7361452.Peer-Reviewed Original ResearchConceptsIntracellular free calciumFormation of erythroid coloniesCFU-E.Erythroid coloniesFree calciumR-EPOSpleens of mice treated with phenylhydrazineCalcium ionophoreCFU-ERecombinant erythropoietinFluorescent dye indo-1Growth of CFU-EEffect of recombinant erythropoietinDye indo-1Action of EpoEpo-responsive cellsErythropoietin-responsive cellsNonhematopoietic progenitorsColony-forming unitsIndo-1Spleen cellsErythroid cellsMac-1Acute changesColony growthCa2+ Transients Induced by Thyrotropin-Releasing Hormone Rapidly Lose Their Ability to Cause Release of Prolactin
Law G, Pachter J, Dannies P. Ca2+ Transients Induced by Thyrotropin-Releasing Hormone Rapidly Lose Their Ability to Cause Release of Prolactin. Endocrinology 1989, 3: 539-546. PMID: 2501668, DOI: 10.1210/mend-3-3-539.Peer-Reviewed Original ResearchConceptsPulses of TRHPRL releasePRL secretionCytosolic free calcium concentrationPost-receptor stepsRat anterior pituitary glandThyrotropin-releasing hormoneRelease of prolactinIndicator indo-1Anterior pituitary glandFree calcium concentrationRelationship of changesContinuous administrationSustained elevationNM TRHPituitary glandIndo-1TRHFluorescent Ca2Calcium concentrationRefractory stateTransient spikeSecretionMinReleaseAbility of repetitive Ca2+ spikes to stimulate prolactin release is frequency dependent
Law G, Pachter J, Dannies P. Ability of repetitive Ca2+ spikes to stimulate prolactin release is frequency dependent. Biochemical And Biophysical Research Communications 1989, 158: 811-816. PMID: 2537637, DOI: 10.1016/0006-291x(89)92794-0.Peer-Reviewed Original ResearchConceptsProlactin releaseAnterior pituitary cellsRelease of prolactinSustained elevated levelsCytosolic free Ca2Amount of prolactinSerial declinePeak Ca2Prolactin secretionPerifusion systemPituitary cellsIndo-1Fluorescent Ca2Repetitive Ca2Transient increaseFree Ca2Elevated levelsProlactinMM KClCa2CellsCoincident increaseMinutesReleaseHigh frequency
1988
TRH and BAY K 8644 synergistically stimulate prolactin release but not 45Ca2+ uptake
Pachter J, Law G, Dannies P. TRH and BAY K 8644 synergistically stimulate prolactin release but not 45Ca2+ uptake. American Journal Of Physiology 1988, 255: c633-c640. PMID: 2461093, DOI: 10.1152/ajpcell.1988.255.5.c633.Peer-Reviewed Original ResearchConceptsBay K 8644Thyrotropin-releasing hormoneProlactin secretionAngiotensin IIProlactin releaseChannel agonist Bay K 8644Agonist Bay K 8644Rat anterior pituitary cellsFluorescent indicator indo-1Anterior pituitary cellsDihydropyridine-sensitive Ca2Indicator indo-1Primary cultured cellsSecretory peaksPituitary cellsSubsequent stimulationIndo-1Transient increaseCytosolic Ca2GH4C1 cellsPrimary culturesSecretionUntreated cellsAdditional effectCultured cells
1987
CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction.
Mentzer SJ, Smith BR, Barbosa JA, Crimmins MA, Herrmann SH, Burakoff SJ. CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction. The Journal Of Immunology 1987, 138: 1325-30. PMID: 3543126, DOI: 10.4049/jimmunol.138.5.1325.Peer-Reviewed Original ResearchConceptsHLA-A2CTL clonesHLA-B7Target cellsAntigen recognitionHuman CTL clonesTarget cell lysisCalcium-sensitive dye indo-1Cytolytic T lymphocytesCTL-target interactionDye indo-1CTL-target cell interactionAntigen-specific receptorsT cell receptorCell surface moleculesCTL activationT lymphocytesHuman CTLIndo-1LFA-1Free calciumCell receptorFlow cytometrySurface moleculesCell interactions
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