2004
Cytoplasmic localization of calcium/calmodulin‐dependent protein kinase I‐α depends on a nuclear export signal in its regulatory domain
Stedman DR, Uboha NV, Stedman TT, Nairn AC, Picciotto MR. Cytoplasmic localization of calcium/calmodulin‐dependent protein kinase I‐α depends on a nuclear export signal in its regulatory domain. FEBS Letters 2004, 566: 275-280. PMID: 15147908, DOI: 10.1016/j.febslet.2004.04.042.Peer-Reviewed Original ResearchMeSH KeywordsActive Transport, Cell NucleusAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 1Calcium-Calmodulin-Dependent Protein KinasesConsensus SequenceCytoplasmEnzyme ActivationKaryopherinsMicroscopy, FluorescenceNuclear Localization SignalsPC12 CellsProtein Structure, TertiaryRatsReceptors, Cytoplasmic and NuclearRecombinant Fusion ProteinsSubcellular FractionsTransfectionConceptsNuclear export signalExport signalRegulatory domainCytoplasmic localizationCalmodulin-dependent protein kinase ICalcium/calmodulin-dependent protein kinase IRev-like nuclear export signalProtein kinase IUbiquitous cytosolic enzymeCalcium/calmodulinTranscriptional regulationNuclear exportKinase INuclear proteinsNuclear entryCatalytic coreCytosolic enzymeI alphaSequenceCRM1VitroMutantsLocalizationCalmodulinDomain
1999
Gene organisation determines evolution of function in the chicken MHC
Kaufman J, Jacob J, Shaw J, Walker B, Milne S, Beck S, Salomonsen J. Gene organisation determines evolution of function in the chicken MHC. Immunological Reviews 1999, 167: 101-117. PMID: 10319254, DOI: 10.1111/j.1600-065x.1999.tb01385.x.Peer-Reviewed Original ResearchConceptsClass II beta genesClass I genesExpressed class I moleculePeptide-binding specificityI geneBeta geneMultigene familyC4 genesI alphaClass III region genesExpressed class I genesMinimal essential MHCB-F/B-L regionRfp-Y regionCell surface expression levelsChicken genomeGene organisationEvolution of functionRRNA geneClass II alphaDO geneRfp-YChicken MHCTapasin geneGenes
1997
α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor
Krasnoperov V, Bittner M, Beavis R, Kuang Y, Salnikow K, Chepurny O, Little A, Plotnikov A, Wu D, Holz R, Petrenko A. α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor. Neuron 1997, 18: 925-937. PMID: 9208860, DOI: 10.1016/s0896-6273(00)80332-3.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBrain ChemistryCalciumCattleChromaffin GranulesCloning, MolecularCOS CellsDimerizationExocytosisGTP-Binding ProteinsMembrane ProteinsMolecular Sequence DataProtein PrecursorsQa-SNARE ProteinsRatsReceptors, Cell SurfaceReceptors, PeptideRecombinant ProteinsSensory Receptor CellsSequence AlignmentSequence Homology, Amino AcidSignal TransductionSpider VenomsTissue DistributionConceptsG protein-coupled receptorsAlpha-latrotoxin receptorNeuronal G protein-coupled receptorNovel orphan G-protein-coupled receptorI alphaCalcium-independent receptorSecretin receptor familyOrphan G protein-coupled receptorRegulation of neurosecretionEndogenous proteolytic cleavageMolecular cloningPrecursor polypeptideSerpentine receptorsCIRLFusion complexExtracellular bindingAlpha-LatrotoxinFunctional expressionReceptor familyProteolytic cleavagePresynaptic receptorsAffinity columnNeurotransmitter releaseStable complexesPresynaptic neurotoxins
1996
The chicken beta 2-microglobulin gene is located on a non-major histocompatibility complex microchromosome: a small, G+C-rich gene with X and Y boxes in the promoter.
Riegert P, Andersen R, Bumstead N, Döhring C, Dominguez-Steglich M, Engberg J, Salomonsen J, Schmid M, Schwager J, Skjødt K, Kaufman J. The chicken beta 2-microglobulin gene is located on a non-major histocompatibility complex microchromosome: a small, G+C-rich gene with X and Y boxes in the promoter. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 1243-1248. PMID: 8577748, PMCID: PMC40064, DOI: 10.1073/pnas.93.3.1243.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase CompositionBase Sequencebeta 2-MicroglobulinBlotting, SouthernChickensChromosome MappingCloning, MolecularConsensus SequenceCrosses, GeneticDNADNA, ComplementaryEnhancer Elements, GeneticErythrocytesFemaleGenes, MHC Class IHumansIn Situ HybridizationMajor Histocompatibility ComplexMaleMolecular Sequence DataPolymorphism, GeneticPolymorphism, Restriction Fragment LengthPromoter Regions, GeneticRestriction MappingSequence Homology, Nucleic AcidT-LymphocytesConceptsY-boxHigh G+C contentBeta 2-microglobulin geneDeletion of DNARestriction fragment length polymorphismInterferon regulatory elementSubunit of major histocompatibility complexFragment length polymorphismG+C contentGenome organizationGenomic clonesG+C-richAntigenic peptides to T lymphocytesPeptides to T lymphocytesRegulatory elementsCoding regionMicrochromosomesPromoter regionBackcross familiesChicken MHCLength polymorphismMHC genesGenesCongenic linesI alpha
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