2025
Clinical outcomes and care for spontaneous bacterial peritonitis: A national cohort study.
Serper M, Tang H, Zhang S, McCullough A, Kaplan D, Taddei T, Mahmud N. Clinical outcomes and care for spontaneous bacterial peritonitis: A national cohort study. Hepatology 2025 PMID: 39879583, DOI: 10.1097/hep.0000000000001251.Peer-Reviewed Original ResearchIn-Hospital MortalityImprove care outcomesPopulation-based studyNational cohort studyQuality measuresHazard of mortalityPost-discharge mortalityNational cohort of patientsCare outcomesSpontaneous bacterial peritonitisInformal careHealth systemPatient clinical factorsAcute kidney injuryBundle componentsRecurrent spontaneous bacterial peritonitisNational cohortCohort studyIncidence of stage 3In-HospitalClinical factorsStage 3Cohort of patientsCumulative incidenceBacterial peritonitis
2024
Validation and epidemiologic definition of the novel steatotic liver disease nomenclature in a national United States cohort with cirrhosis
Mezzacappa C, Ochoa-Allemant P, Serper M, Taddei T, John B, Kaplan D, Mahmud N. Validation and epidemiologic definition of the novel steatotic liver disease nomenclature in a national United States cohort with cirrhosis. Clinical Gastroenterology And Hepatology 2024 PMID: 39689774, PMCID: PMC12167392, DOI: 10.1016/j.cgh.2024.10.035.Peer-Reviewed Original ResearchAlcohol-associated liver diseaseCardiometabolic risk factorsAlcohol use disorderSteatotic liver diseaseLiver diseaseLow high-density lipoproteinChild-Turcotte-Pugh classIncidence rateIncident hepatocellular carcinomaIncreased alcohol intakeAlcohol useClinically relevant definitionAll-Cause MortalityHigher hazard of mortalityNational cohort of veteransUnited States cohortCohort of veteransAcute cardiac eventsHigh-density lipoproteinHazard of mortalityHazardous alcohol useAlcohol intakeCardiac eventsAlcohol exposureHepatocellular carcinomaCare interruptions and mortality among adults in Europe and North America
Trickey A, Zhang L, Rentsch C, Pantazis N, Izquierdo R, Antinori A, Leierer G, Burkholder G, Cavassini M, Palacio-Vieira J, Gill M, Teira R, Stephan C, Obel N, Vehreschild J, Sterling T, Van Der Valk M, Bonnet F, Crane H, Silverberg M, Ingle S, Sterne J. Care interruptions and mortality among adults in Europe and North America. AIDS 2024, 38: 1533-1542. PMID: 38742863, PMCID: PMC11239093, DOI: 10.1097/qad.0000000000003924.Peer-Reviewed Original ResearchCare interruptionsMortality riskCohort studyHazard ratioAnalysis of cohort studiesAntiretroviral therapyCare of peopleRobust to sensitivity analysesMortality hazard ratioCrude mortality rateHazard of mortalityAntiretroviral therapy initiationObservational cohort studyAntiretroviral therapy startUninterrupted careFollow-up groupCareAssociated with adverse outcomesPWHCox regressionAdverse outcomesFollow-up timeMortality rateCompare hazardsComposite outcome
2023
Frailty Resilience Score: A Novel Measure of Frailty Resilience Associated With Protection From Frailty and Survival
Milman S, Lerman B, Ayers E, Zhang Z, Sathyan S, Levine M, Ye K, Gao T, Higgins-Chen A, Barzilai N, Verghese J. Frailty Resilience Score: A Novel Measure of Frailty Resilience Associated With Protection From Frailty and Survival. The Journals Of Gerontology Series A 2023, 78: 1771-1777. PMID: 37246648, PMCID: PMC10562888, DOI: 10.1093/gerona/glad138.Peer-Reviewed Original ResearchConceptsMultivariable-adjusted analysesHazard of mortalityPhenotypic frailtyBaseline frailtyOverall survivalEffective therapyHigh riskFrailtyResilience AssociatedOlder adultsGenetic riskIdentification of factorsReliable predictorMortalityResilience scoresSurvivalProteomic profilesRiskReliable measureDeviation increaseTherapyCohort
2022
Joint Models for Estimating Determinants of Cognitive Decline in the Presence of Survival Bias
Davis-Plourde KL, Mayeda ER, Lodi S, Filshtein T, Beiser A, Gross AL, Seshadri S, Glymour MM, Tripodis Y. Joint Models for Estimating Determinants of Cognitive Decline in the Presence of Survival Bias. Epidemiology 2022, 33: 362-371. PMID: 35383644, DOI: 10.1097/ede.0000000000001472.Peer-Reviewed Original ResearchConceptsCognitive declineSurvival biasCox proportional hazards modelHazard of mortalityProportional hazards modelExposure of interestEffect of educationEffects of exposureHazards modelDementia diagnosisAlzheimer's diseaseMixed-effects modelsGEE modelMortalitySurvivalInconsistent resultsDiseaseInformative attritionStudy dataAttrition weightsExposureBlood Pressure Trajectories and Outcomes for Veterans Presenting at VA Medical Centers with a Stroke or Transient Ischemic Attack
Arling G, Perkins A, Myers LJ, Sico JJ, Bravata DM. Blood Pressure Trajectories and Outcomes for Veterans Presenting at VA Medical Centers with a Stroke or Transient Ischemic Attack. The American Journal Of Medicine 2022, 135: 889-896.e1. PMID: 35292287, DOI: 10.1016/j.amjmed.2022.02.012.Peer-Reviewed Original ResearchConceptsSystolic blood pressure trajectoriesTransient ischemic attackSystolic blood pressureBlood pressure trajectoriesBlood pressureAntihypertensive medicationsIschemic attackPressure trajectoriesHigher systolic blood pressureLower systolic blood pressureCox proportional hazards modelBlood pressure reductionBlood pressure controlEmergency department visitsHazard of mortalityProportional hazards modelVA Medical CenterMedication intensificationCause mortalityVascular eventsIschemic strokeRetrospective cohortDepartment visitsHypertension managementIndex event
2020
Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV.
Pelloquin R, Abdo M, MaWhinney S, Jankowski CM, Erlandson KM. Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 85: 372-378. PMID: 32732769, PMCID: PMC7572796, DOI: 10.1097/qai.0000000000002455.Peer-Reviewed Original ResearchConceptsPhysical function measuresTime-dependent receiverVACS IndexPhysical functionGrip strengthFunction measuresCross-sectional cohort studyPhysical function impairmentPhysical function variablesSex-adjusted modelsHazard of mortalityMiddle-aged populationSpecific patient subpopulationsPrediction of survivalMiddle-aged adultsOnly significant improvementElectronic health recordsVACS scoresCohort studyFrailty toolsFunction impairmentPatient subpopulationsVAC indexMortality predictionPWH
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