2019
Molecular recognition of nucleosomes by binding partners
Kale S, Goncearenco A, Markov Y, Landsman D, Panchenko A. Molecular recognition of nucleosomes by binding partners. Current Opinion In Structural Biology 2019, 56: 164-170. PMID: 30991239, PMCID: PMC6656623, DOI: 10.1016/j.sbi.2019.03.010.Peer-Reviewed Original ResearchConceptsEpigenetic signaling pathwaysChromatin factorsEukaryotic cellsHistone tailsChromatin packingInteraction landscapeLinker DNAMolecular recognitionNucleosomesHistone coreIntrinsic disorderSignaling pathwaysBroad repertoireFurther complexityBasic mechanismsChromatinDNARegulationPathwayRepertoireCellsPartnersTailLandscape
2018
Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes
Grochowski CM, Gu S, Yuan B, Julia T, Brennand KJ, Sebat J, Malhotra D, McCarthy S, Rudolph U, Lindstrand A, Chong Z, Levy DL, Lupski JR, Carvalho CMB. Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes. Human Mutation 2018, 39: 939-946. PMID: 29696747, PMCID: PMC5995661, DOI: 10.1002/humu.23537.Peer-Reviewed Original ResearchConceptsWhole-genome sequencingSmall supernumerary marker chromosomeChromosomal fragmentsMarker chromosomesGenomic structureComparative genomic hybridization analysisSupernumerary marker chromosomeGenomic hybridization analysisTemporal originHybridization analysisArray comparative genomic hybridization analysisChromosome 9Short armRepair mechanismsMarker genotypesChromosomesPrecise architectureProband's maternal grandmotherStructural variationsPsychiatric phenotypesFurther complexityFragmentsDuplicationSequencingPhenotype
2008
Fibroblast Growth Factor-2 in Angiogenesis
Presta M, Mitola S, Dell'Era P, Leali D, Nicoli S, Moroni E, Rusnati M. Fibroblast Growth Factor-2 in Angiogenesis. 2008, 77-88. DOI: 10.1007/978-0-387-71518-6_7.Peer-Reviewed Original ResearchFibroblast growth factor-2Growth factor 2Signal transduction pathwaysGrowth factorExtracellular matrix-associated moleculesFactor 2Cell surface receptorsTyrosine kinase receptorsMatrix-associated moleculesHeparan sulfate proteoglycanTransduction pathwaysExtracellular interactionsEndothelial cell surface receptorsKinase receptorsSurface receptorsComplex networksAngiogenic growth factorsMechanism of actionAngiogenic potentialPathological conditionsBiological activityEndothelial cellsAngiogenic activityTumor growthFurther complexity
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