2022
Chest pain and coronary endothelial dysfunction after recovery from COVID‐19: A case series
Shah SM, Odanovic N, Kunnirickal S, Feher A, Pfau SE, Spatz ES. Chest pain and coronary endothelial dysfunction after recovery from COVID‐19: A case series. Clinical Case Reports 2022, 10: e05612. PMID: 35425611, PMCID: PMC8991764, DOI: 10.1002/ccr3.5612.Peer-Reviewed Case Reports and Technical Notes
2015
Thrombotic Microangiopathy, Cancer, and Cancer Drugs
Izzedine H, Perazella MA. Thrombotic Microangiopathy, Cancer, and Cancer Drugs. American Journal Of Kidney Diseases 2015, 66: 857-868. PMID: 25943718, DOI: 10.1053/j.ajkd.2015.02.340.Peer-Reviewed Original ResearchConceptsDrug-induced thrombotic microangiopathyThrombotic microangiopathyAnti-vascular endothelial growth factor agentsEndothelial growth factor agentsLong-term kidney injuryManagement of TMACell damageGrowth factor agentsAnti-VEGF agentsEndothelial cell damageType I agentsChemotherapy regimensDrug interruptionFactor agentsKidney injuryImmunologic basisClinical courseFunctional recoveryImmunosuppressive agentsKidney functionCertain malignanciesI agentsPhysician guidanceAnticancer therapySuccessful diagnosis
2014
The Tumor Radiobiology of SRS and SBRT: Are More Than the 5 Rs Involved?
Brown JM, Carlson DJ, Brenner DJ. The Tumor Radiobiology of SRS and SBRT: Are More Than the 5 Rs Involved? International Journal Of Radiation Oncology • Biology • Physics 2014, 88: 254-262. PMID: 24411596, PMCID: PMC3893711, DOI: 10.1016/j.ijrobp.2013.07.022.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsCell CycleCell HypoxiaCell ProliferationCell SurvivalDNA DamageDNA RepairDose Fractionation, RadiationEndothelial CellsHumansLinear ModelsMelanomaMiceModels, BiologicalNeoplasmsOxygen ConsumptionRadiation ToleranceRadiobiologyRadiosurgeryRelative Biological Effectiveness
2007
Semaphorin3a disrupts podocyte foot processes causing acute proteinuria
Tapia R, Guan F, Gershin I, Teichman J, Villegas G, Tufro A. Semaphorin3a disrupts podocyte foot processes causing acute proteinuria. Kidney International 2007, 73: 733-740. PMID: 18075495, DOI: 10.1038/sj.ki.5002726.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAnimalsCytoskeletal ProteinsDown-RegulationGlomerular Basement MembraneGlomerular Filtration RateIntracellular Signaling Peptides and ProteinsMaleMembrane ProteinsMiceMice, Inbred StrainsPermeabilityPodocytesProteinuriaRecombinant ProteinsSemaphorin-3AVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-1Vascular Endothelial Growth Factor Receptor-2ConceptsPodocyte foot process effacementNephrotic range proteinuriaEndothelial cell damageVascular endothelial growth factorSlit diaphragm protein podocinFoot process effacementEndothelial growth factorReceptor 2 signalingVascular endothelial growth factor receptor 2 signalingAcute proteinuriaRange proteinuriaReceptor expressionVascular endothelial growth factor 165Process effacementBarrier homeostasisAdult mouse kidneyUltrastructural abnormalitiesSemaphorin3AEndothelial cellsCell damageGrowth factorMouse kidneyGuidance proteinsProteinuriaDownregulation
1999
Thrombomodulin: A New Marker for Placental Abruption
Magriples U, Chan D, Bruzek D, Copel J, Hsu C. Thrombomodulin: A New Marker for Placental Abruption. Thrombosis And Haemostasis 1999, 81: 32-34. PMID: 9974370, DOI: 10.1055/s-0037-1614413.Peer-Reviewed Original ResearchConceptsPlacental abruptionAcute placental abruptionAbnormal coagulation profileProspective cohort studyEndothelial cell damageCohort studyCoagulation profilePathologic evidencePregnant womenKleihauer-BetkeAbruptionGroup 2Group 1Placental syncytiotrophoblastClinical diagnosisThrombomodulinCell damageSpecific markersNew markersPatientsMarkersDeliverySyncytiotrophoblastDiagnosisWomen
1986
Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.
Bevilacqua MP, Pober JS, Majeau GR, Fiers W, Cotran RS, Gimbrone MA. Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 4533-4537. PMID: 3487091, PMCID: PMC323768, DOI: 10.1073/pnas.83.12.4533.Peer-Reviewed Original ResearchConceptsRecombinant tumor necrosis factorCultured human vascular endotheliumTumor necrosis factorIL-1Procoagulant activityHuman vascular endotheliumNecrosis factorInterleukin-1Vascular endotheliumTissue factor-like procoagulant activityInduction of PCANatural human interleukin-1Human recombinant tumor necrosis factorEndothelial cell damageCellular procoagulant activityEndothelial procoagulant activityRecombinant IL-1Specific neutralizing antiseraHuman interleukin-1Effects of TNFInitiation of coagulationIliac arteryMaximal dosesPCA responseSaphenous vein
1985
Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.
Bevilacqua MP, Pober JS, Wheeler ME, Cotran RS, Gimbrone MA. Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. Journal Of Clinical Investigation 1985, 76: 2003-2011. PMID: 3877078, PMCID: PMC424265, DOI: 10.1172/jci112200.Peer-Reviewed Original ResearchConceptsEndothelial-leukocyte adhesionHuman vascular endotheliumIL-1Leukocyte adhesionVascular endotheliumCultured human vascular endotheliumLeukocyte-vessel wall interactionsIL-1 pretreatmentEndothelial cell damageEndothelial monolayersSites of inflammationIL-1 treatmentHuman umbilical vein endothelial monolayersCertain vascular diseasesPromyelocytic cell line HL-60Polymorphonuclear leukocyte adhesionIL-1 inductionImmune mediatorsHuman endothelial cellsEndothelial adhesivityVascular diseaseBlood leukocytesInterleukin-1Leukocyte cell linesCell line U937
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