2015
Thrombotic Microangiopathy, Cancer, and Cancer Drugs
Izzedine H, Perazella MA. Thrombotic Microangiopathy, Cancer, and Cancer Drugs. American Journal Of Kidney Diseases 2015, 66: 857-868. PMID: 25943718, DOI: 10.1053/j.ajkd.2015.02.340.Peer-Reviewed Original ResearchConceptsDrug-induced thrombotic microangiopathyThrombotic microangiopathyAnti-vascular endothelial growth factor agentsEndothelial growth factor agentsLong-term kidney injuryManagement of TMACell damageGrowth factor agentsAnti-VEGF agentsEndothelial cell damageType I agentsChemotherapy regimensDrug interruptionFactor agentsKidney injuryImmunologic basisClinical courseFunctional recoveryImmunosuppressive agentsKidney functionCertain malignanciesI agentsPhysician guidanceAnticancer therapySuccessful diagnosis
2013
Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity
Ghosh A, Dogan Y, Moroz M, Holland A, Yim N, Rao U, Young L, Tannenbaum D, Masih D, Velardi E, Tsai J, Jenq R, Penack O, Hanash A, Smith O, Piersanti K, Lezcano C, Murphy G, Liu C, Palomba M, Sauer M, Sadelain M, Ponomarev V, van den Brink M. Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity. Journal Of Clinical Investigation 2013, 123: 2654-2662. PMID: 23676461, PMCID: PMC3668849, DOI: 10.1172/jci66301.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsAntigen-Presenting CellsCell Line, TumorCytotoxicity, ImmunologicGraft RejectionGraft vs Host DiseaseHEK293 CellsHumansImmunotherapy, AdoptiveLeukemia, Lymphocytic, Chronic, B-CellMiceMice, Inbred BALB CMice, Inbred C57BLNeoplasm TransplantationT-LymphocytesTNF-Related Apoptosis-Inducing LigandConceptsGVT responseT cellsAllo-HSCTAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationCellular therapyAbsence of GVHDDR5-dependent mannerDonor T cellsAlloreactive T cellsStem cell transplantationChronic lymphocytic leukemia cellsPrecursor T cellsThird-party donorsLymphocytic leukemia cellsApoptosis-inducing ligandGVT activityHost diseaseCell transplantationCurative potentialTumor responseGVHDCertain malignanciesMouse modelHuman leukemia cell lines
2008
Fertility Issues and Options in Young Women with Cancer
Oktay K, Sönmezer M. Fertility Issues and Options in Young Women with Cancer. Recent Results In Cancer Research 2008, 178: 203-224. PMID: 18080455, DOI: 10.1007/978-3-540-71274-9_18.Peer-Reviewed Original ResearchConceptsFemale cancersHematopoietic stem cell transplantationLong-term complicationsStem cell transplantationCurrent treatment modalitiesNew cancer casesMultiagent chemotherapyCell transplantationCure rateTreatment modalitiesCancer incidenceSurgical techniqueCancer casesCertain malignanciesRadiation therapyFertility issuesCancerYoung womenDeath rate
1998
Malignancy may adversely influence the quality and behaviour of oocytes.
Pal L, Leykin L, Schifren J, Isaacson K, Chang Y, Nikruil N, Chen Z, Toth T. Malignancy may adversely influence the quality and behaviour of oocytes. Human Reproduction 1998, 13: 1837-1840. PMID: 9740435, DOI: 10.1093/humrep/13.7.1837.Peer-Reviewed Original ResearchConceptsMalignant diseaseMalignant disordersAge-matched patientsCell of originTubal infertilityIVF cyclesOvarian stimulationDefinitive treatmentCase seriesCertain malignanciesNeoplastic processPatientsComparable total numberMature oocytesMalignancyFertilization rateDiseasePotential fertilityApparent adverse influenceOocytesPoor qualityDisordersTotal numberAdverse influenceInfertility
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