2023
Depression in mothers at childhood: Direct and indirect association with problematic gaming in late adolescence/young adulthood
Roza T, Rabelo-da-Ponte F, Spritzer D, Hoffmann M, Massuda R, Salum G, Miguel E, Rohde L, Pan P, Kessler F, Gadelha A, Passos I. Depression in mothers at childhood: Direct and indirect association with problematic gaming in late adolescence/young adulthood. Journal Of Psychiatric Research 2023, 159: 14-21. PMID: 36652752, DOI: 10.1016/j.jpsychires.2023.01.022.Peer-Reviewed Original ResearchConceptsAdolescence/young adulthoodMothers' depressionLate adolescence/young adulthoodRisk factorsSchool-based cohortYoung adulthoodMultiple confounding factorsLogistic regression modelsInverse probability weightsConfounding factorsExternalizing disordersInternalizing disordersDepressionPotential roleDisordersChildhoodMediatorsRegression modelsMothersSexAdulthoodInternalizing psychopathologySignificant mediatorMediation analysisAssociation
2022
Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood?
Saavedra LM, Morgan-López AA, West SG, Alegría M, Silverman WK. Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood? Prevention Science 2022, 24: 1622-1635. PMID: 36057023, DOI: 10.1007/s11121-022-01422-z.Peer-Reviewed Original ResearchConceptsStudy-related treatmentYoung adulthoodPropensity scoreLong-term followDrug use disordersAdolescence/young adulthoodQuasi-experimental designLate adolescence/young adulthoodClinical trialsSubstance use disorder severityLong-term effectsChild anxiety disordersEpidemiological studiesIntegrative data analysisAnxiety disorder treatmentUse disordersDisorder treatmentAnxiety disordersControl participantsEpidemiological sampleClinical samplesDisorder severityTrialsLong-term assessmentDisorders
2018
Gray and white matter differences in adolescents and young adults with prior suicide attempts across bipolar and major depressive disorders
Fan S, Lippard ETC, Sankar A, Wallace A, Johnston JAY, Wang F, Pittman B, Spencer L, Oquendo MA, Blumberg HP. Gray and white matter differences in adolescents and young adults with prior suicide attempts across bipolar and major depressive disorders. Journal Of Affective Disorders 2018, 245: 1089-1097. PMID: 30699851, PMCID: PMC6903411, DOI: 10.1016/j.jad.2018.11.095.Peer-Reviewed Original ResearchConceptsMajor depressive disorderYoung adult suicide attemptersNon-suicide attemptersAdult suicide attemptersBipolar disorderSuicide attemptersFractional anisotropyDepressive disorderGM volumePrevention strategiesBrain circuitryYoung adultsBrain circuitry abnormalitiesAdolescents/young adultsWhite matter fractional anisotropyEarly prevention strategiesAdolescence/young adulthoodMagnetic resonance scanningWhite matter alterationsGray matter volumeSuicide prevention strategiesPrior suicide attemptsWM fractional anisotropyWhole-brain analysisWhite matter differences
2017
Longitudinal Diffusion Tensor Imaging Study of Adolescents and Young Adults With Bipolar Disorder
Weathers J, Lippard ETC, Spencer L, Pittman B, Wang F, Blumberg HP. Longitudinal Diffusion Tensor Imaging Study of Adolescents and Young Adults With Bipolar Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2017, 57: 111-117. PMID: 29413143, PMCID: PMC5806147, DOI: 10.1016/j.jaac.2017.11.014.Peer-Reviewed Original ResearchConceptsAdolescents/young adultsDiffusion tensor imaging studyAdolescence/young adulthoodLongitudinal diffusion tensor imaging studyBipolar disorderVentral prefrontal cortexFractional anisotropyYoung adultsHealthy controlsWhite matterImaging studiesUncinate fasciculusYoung adulthoodUF fractional anisotropyWhole-brain analysisClinical factorsTime-related changesSignificant interactionLongitudinal neuroimagingPrefrontal cortexDTI scansNeurodevelopmental pathophysiologyAdultsAgeTrait features
2009
Preliminary evidence for progressive prefrontal abnormalities in adolescents and young adults with bipolar disorder
KALMAR JH, WANG F, SPENCER L, EDMISTON E, LACADIE CM, MARTIN A, CONSTABLE RT, DUNCAN JS, STAIB LH, PAPADEMETRIS X, BLUMBERG HP. Preliminary evidence for progressive prefrontal abnormalities in adolescents and young adults with bipolar disorder. Journal Of The International Neuropsychological Society 2009, 15: 476-481. PMID: 19402934, PMCID: PMC2852397, DOI: 10.1017/s1355617709090584.Peer-Reviewed Original ResearchConceptsAdolescents/young adultsVentral prefrontal cortexBipolar disorderYoung adultsBrain volume changesRostral anterior cingulate cortexPrevious cross-sectional studiesCross-sectional studyAdolescence/young adulthoodHigh-resolution magnetic resonanceAnterior cingulate cortexPreliminary evidenceVolume abnormalitiesHealthy comparison participantsPrefrontal abnormalitiesGreater volume lossCingulate cortexRegional volumesPrefrontal cortexModest sample sizeYoung adulthoodAdultsRostral PFCComparison participantsAbnormalities
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