2025
World Health Organization risk drinking level reductions as treatment outcomes in PTSD and substance use disorder trials
López-Castro T, Gette J, Back S, Blakey S, Killeen T, Morgan-Lopez A, Norman S, Ruglass L, Saavedra L, McGovern M, Petrakis I, Sonne S, Ehring T, Brady K, Hien D. World Health Organization risk drinking level reductions as treatment outcomes in PTSD and substance use disorder trials. Drug And Alcohol Dependence 2025, 275: 112837. PMID: 40850028, DOI: 10.1016/j.drugalcdep.2025.112837.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderSubstance use disordersAlcohol use disorderDrinking outcomesUse disorderDrinking levelsComorbid posttraumatic stress disorderWorld Health Organization risk drinking levelsWorld Health Organization’s risk levelHeavy drinkingRisk drinking levelsRisk level reductionEnd-of-treatmentSubstance use disorder trialsIntegrative data analysisStress disorderAlcohol outcomesDrinking reductionPrimary treatment endpointWorld Health OrganizationAbstinencePharmacological treatmentTreatment responseTreatment outcomesPharmacological interventions
2024
Corrigendum to ‘Integrative data analysis of clinical trials network studies to examine the impact of psychosocial treatments for Black people who use cocaine: Study protocol’ [Contemporary Clinical Trials 133 (2023) 107329].
Haeny A, McCuistian C, Burlew A, Ruglass L, Espinosa A, Jordan A, Roundtree C, Lopez J, Morgan-Lopez A. Corrigendum to ‘Integrative data analysis of clinical trials network studies to examine the impact of psychosocial treatments for Black people who use cocaine: Study protocol’ [Contemporary Clinical Trials 133 (2023) 107329]. Contemporary Clinical Trials 2024, 147: 107740. PMID: 39578191, DOI: 10.1016/j.cct.2024.107740.Peer-Reviewed Original ResearchImpact of psychosocial treatmentsClinical Trials Network studyIntegrative data analysisPsychosocial treatments
2023
Integrative data analysis of clinical trials network studies to examine the impact of psychosocial treatments for black people who use cocaine: Study protocol
Haeny A, McCuistian C, Burlew A, Ruglass L, Espinosa A, Jordan A, Roundtree C, Lopez J, Morgan-López A. Integrative data analysis of clinical trials network studies to examine the impact of psychosocial treatments for black people who use cocaine: Study protocol. Contemporary Clinical Trials 2023, 133: 107329. PMID: 37652354, PMCID: PMC10635737, DOI: 10.1016/j.cct.2023.107329.Peer-Reviewed Original ResearchConceptsStudy protocolPsychosocial treatmentsPsychostimulant useTreatment effectivenessRandomized clinical trialsCocaine use severityClinical trialsInclusion criteriaOutcome measuresStudy-level moderatorsGeneral populationUse disordersTreatment approachesScale scoreTreatment interventionsComparative effectivenessSynthetic opioidsCocaine useIntegrative data analysisNIDA CTNDeath rateBehavioral interventionsUse severityCTN studiesCocaine
2022
Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood?
Saavedra LM, Morgan-López AA, West SG, Alegría M, Silverman WK. Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood? Prevention Science 2022, 24: 1622-1635. PMID: 36057023, DOI: 10.1007/s11121-022-01422-z.Peer-Reviewed Original ResearchConceptsStudy-related treatmentYoung adulthoodPropensity scoreLong-term followDrug use disordersAdolescence/young adulthoodQuasi-experimental designLate adolescence/young adulthoodClinical trialsSubstance use disorder severityLong-term effectsChild anxiety disordersEpidemiological studiesIntegrative data analysisAnxiety disorder treatmentUse disordersDisorder treatmentAnxiety disordersControl participantsEpidemiological sampleClinical samplesDisorder severityTrialsLong-term assessmentDisorders
2019
Trajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis
Skriner LC, Chu BC, Kaplan M, Bodden DHM, Bögels SM, Kendall PC, Nauta MH, Silverman WK, Wood JJ, Barker DH, de la Torre J, Saavedra L, Xie MG. Trajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis. Journal Of Consulting And Clinical Psychology 2019, 87: 198-211. PMID: 30570308, DOI: 10.1037/ccp0000367.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyGrowth mixture modelingIntegrative data analysisParent-reported anxiety symptomsFamily cognitive-behavioral therapySymptom changeTrajectory classesYouth-reported symptomsParent-reported symptomsMixture modelingPredictors of trajectoriesItem response theory modelsAnxious youthImprovement classesAnxiety symptomsRapid respondersResponse classesYouthTheory modelPredictorsDistinct patternsOlder agePredictors of responseMembershipSymptoms
2017
Personality predicts mortality risk: An integrative data analysis of 15 international longitudinal studies
Graham E, Rutsohn J, Turiano N, Bendayan R, Batterham P, Gerstorf D, Katz M, Reynolds C, Sharp E, Yoneda T, Bastarache E, Elleman L, Zelinski E, Johansson B, Kuh D, Barnes L, Bennett D, Deeg D, Lipton R, Pedersen N, Piccinin A, Spiro A, Muniz-Terrera G, Willis S, Schaie K, Roan C, Herd P, Hofer S, Mroczek D. Personality predicts mortality risk: An integrative data analysis of 15 international longitudinal studies. Journal Of Research In Personality 2017, 70: 174-186. PMID: 29230075, PMCID: PMC5722274, DOI: 10.1016/j.jrp.2017.07.005.Peer-Reviewed Original ResearchPattern of protective effectsLow conscientiousnessHigh neuroticismIntegrative data analysisPersonality traitsOlder baseline ageInternational longitudinal studyExtraversionNeuroticismLongitudinal studyPredictor of mortality riskBaseline ageU.S. studiesPersonsMortality riskAgreeablenessConscientiousnessPredictorsPredictors of mortalityParticipantsTraitsSmokingProtective effectAgeStudy
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