2024
MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume
Blokland G, Maleki N, Jovicich J, Mesholam-Gately R, DeLisi L, Turner J, Shenton M, Voineskos A, Kahn R, Roffman J, Holt D, Ehrlich S, Kikinis Z, Dazzan P, Murray R, Lee J, Sim K, Lam M, de Zwarte S, Walton E, Kelly S, Picchioni M, Bramon E, Makris N, David A, Mondelli V, Reinders A, Oykhman E, Morris D, Gill M, Corvin A, Cahn W, Ho N, Liu J, Gollub R, Manoach D, Calhoun V, Sponheim S, Buka S, Cherkerzian S, Thermenos H, Dickie E, Ciufolini S, Marques T, Crossley N, Purcell S, Smoller J, van Haren N, Toulopoulou T, Donohoe G, Goldstein J, Keshavan M, Petryshen T, del Re E. MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume. International Journal Of Clinical And Health Psychology 2024, 24: 100458. PMID: 38623146, PMCID: PMC11017057, DOI: 10.1016/j.ijchp.2024.100458.Peer-Reviewed Original ResearchIncreased LV volumesLV ratioLateral ventricleLV volumesCorpus callosumEphrin pathwaysSZ probandsHallmarks of schizophreniaEnlarged lateral ventriclesSNP-based heritability estimatesGlobal Assessment of FunctioningBrain MRI scansGlobal functioningCorpus callosum volumeAssessment of functioningClinical dataCC abnormalitiesMicroRNA MIR137MRI scansCC volumeGlobal assessmentMid-anteriorInverse correlationSchizophreniaMIR137
2021
Cerebral Microbleeds and Acute Hematoma Characteristics in the ATACH-2 and MISTIE III Trials
Magid-Bernstein JR, Li Y, Cho SM, Piran PJ, Roh DJ, Gupta A, Shoamanesh A, Merkler A, Zhang C, Avadhani R, Montano N, Iadecola C, Falcone G, Sheth K, Qureshi AI, Rosand J, Goldstein J, Awad I, Hanley D, Kamel H, Ziai WC, Murthy SB. Cerebral Microbleeds and Acute Hematoma Characteristics in the ATACH-2 and MISTIE III Trials. Neurology 2021, 98: e1013-e1020. PMID: 34937780, PMCID: PMC8967392, DOI: 10.1212/wnl.0000000000013247.Peer-Reviewed Original ResearchConceptsSmaller ICH volumeCerebral microbleedsSmall vessel diseaseIntracerebral hemorrhageHematoma expansionHematoma characteristicsICH volumeVessel diseaseNumber of CMBsSmaller baseline hematoma volumesUnderlying small vessel diseasePresence of CMBsCerebral small vessel diseaseAdmission ICH volumeMISTIE III trialPresence of microbleedsClass II evidencePhase 3 trialSeverity of leukoaraiosisPrimary intracerebral hemorrhageBaseline hematoma volumeIndividual patient dataBrain MRI scansLogistic regression modelsAntihypertensive treatment
2020
Structural and functional brain changes in hepatic and neurological Wilson disease
Tinaz S, Arora J, Nalamada K, Vives-Rodriguez A, Sezgin M, Robakis D, Patel A, Constable RT, Schilsky ML. Structural and functional brain changes in hepatic and neurological Wilson disease. Brain Imaging And Behavior 2020, 15: 2269-2282. PMID: 33244627, DOI: 10.1007/s11682-020-00420-5.Peer-Reviewed Original ResearchConceptsSusceptibility-weighted imagingFunctional brain changesBrain changesWD groupWilson's diseaseWhite matter volume lossBilateral superior frontal cortexBilateral anterior corona radiataResting-state functional MRINeurological Wilson's diseaseStructural brain changesCross-sectional studyGender-matched controlsBrain MRI scansAnterior corona radiataSuperior frontal cortexWhite matter integrityFunctional connectivity analysisSignificant striatalThalamic atrophyNeuropsychiatric symptomsHypointense lesionsTreatment strategiesCorpus callosumNeuropsychiatric assessment
2004
Multisystem study of 20 older adults with Williams syndrome
Cherniske EM, Carpenter TO, Klaiman C, Young E, Bregman J, Insogna K, Schultz RT, Pober BR. Multisystem study of 20 older adults with Williams syndrome. American Journal Of Medical Genetics Part A 2004, 131A: 255-264. PMID: 15534874, DOI: 10.1002/ajmg.a.30400.Peer-Reviewed Original ResearchConceptsStandard oral glucose tolerance testingOral glucose tolerance testingNatural historyLong-term natural historyHigh-frequency sensorineural hearing lossFrequency sensorineural hearing lossOlder adultsAbnormal body habitusWilliams syndromeAbnormal glucose toleranceGlucose tolerance testingBone mineral densitySensorineural hearing lossMultiple organ systemsBrain MRI scansYears of ageDiverticular diseaseGastrointestinal symptomsSubclinical hypothyroidismGlucose toleranceMultimodal therapyDEXA scanningBody habitusMineral densityCardiovascular disease
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply