2020
Fetal Bisphenol-A Induced Changes in Murine Behavior and Brain Gene Expression Persisted in Adult-aged Offspring
Wang Z, Alderman MH, Asgari C, Taylor HS. Fetal Bisphenol-A Induced Changes in Murine Behavior and Brain Gene Expression Persisted in Adult-aged Offspring. Endocrinology 2020, 161: bqaa164. PMID: 32926169, PMCID: PMC7609133, DOI: 10.1210/endocr/bqaa164.Peer-Reviewed Original ResearchConceptsUtero exposureLocomotor activityUtero bisphenol A (BPA) exposureBisphenol A (BPA) exposureSignificant decreaseAnxiety-like behaviorDeclarative memory impairmentSex-specific mannerA ExposureFemale miceMale miceBPA exposureRelevant doseMotor coordinationMouse modelMurine behaviourControl animalsNeurobehavioral functionBPA treatmentLocomotor deficitsMemory impairmentOlder ageBrain developmentLong-term memoryBrain gene expressionEstimated Dietary Bisphenol-A Exposure and Adiposity in Samoan Mothers and Children
Heinsberg LW, Bui CNN, Hartle JC, Sereika SM, Choy CC, Wang D, Soti-Ulberg C, Naseri T, Reupena MS, Duckham RL, Park JJ, Hawley NL, Deziel NC. Estimated Dietary Bisphenol-A Exposure and Adiposity in Samoan Mothers and Children. Toxics 2020, 8: 67. PMID: 32887300, PMCID: PMC7560430, DOI: 10.3390/toxics8030067.Peer-Reviewed Original ResearchBody mass indexDietary BPA exposureAbdominal circumferenceBPA exposureModern dietary patternBisphenol A (BPA) exposureMother-child pairsDietary questionnaireMass indexPrevalent obesityFoods/beveragesDietary patternsSamoan mothersSignificant associationEndocrine disruptor bisphenolHigher incomeUnderstudied populationExposure indexMothersChildrenExposureFurther examinationAssociationHousehold-level characteristicsIndexAssessing Endogenous and Exogenous Hormone Exposures and Breast Development in a Migrant Study of Bangladeshi and British Girls
Howland RE, Deziel NC, Bentley GR, Booth M, Choudhury OA, Hofmann JN, Hoover RN, Katki HA, Trabert B, Fox SD, Troisi R, Houghton LC. Assessing Endogenous and Exogenous Hormone Exposures and Breast Development in a Migrant Study of Bangladeshi and British Girls. International Journal Of Environmental Research And Public Health 2020, 17: 1185. PMID: 32069802, PMCID: PMC7068451, DOI: 10.3390/ijerph17041185.Peer-Reviewed Original ResearchConceptsEstrogen metabolitesBPA-glucuronideBreast developmentMigrant studiesBreast cancer incidenceEndogenous estrogen levelsBisphenol A (BPA) exposureExogenous hormone exposureCross-sectional studyBangladeshi girlsTime of interviewUrine spot samplesHazard ratioEstrogen levelsA ExposureCancer incidenceEarlier thelarcheTanner stageUbiquitous exposureHormone exposureThelarcheLiquid chromatography-tandem mass spectrometryConfidence intervalsWhite BritishAdolescent girls
2017
Bisphenol-A exposure in utero programs a sexually dimorphic estrogenic state of hepatic metabolic gene expression
Ilagan Y, Mamillapalli R, Goetz L, Kayani J, Taylor HS. Bisphenol-A exposure in utero programs a sexually dimorphic estrogenic state of hepatic metabolic gene expression. Reproductive Toxicology 2017, 71: 84-94. PMID: 28476547, DOI: 10.1016/j.reprotox.2017.05.001.Peer-Reviewed Original ResearchConceptsBPA exposureGene expressionAdult gene expressionFetal BPA exposureBisphenol A (BPA) exposureMetabolic gene expressionEstrogen receptor alphaExpression of genesBeta gene expressionEstrogenic stateEstrogen treatmentPregnant miceMetabolic disordersE2 stimulationReceptor alphaFetal developmentLipid metabolismDay 9Developmental programmingSexual dimorphismFemale offspringLiverObesityGenesAdult responses
2014
Bisphenol A and Reproductive Health: Update of Experimental and Human Evidence, 2007–2013
Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, Padmanabhan V, Taylor HS, Swan SH, VandeVoort CA, Flaws JA. Bisphenol A and Reproductive Health: Update of Experimental and Human Evidence, 2007–2013. Environmental Health Perspectives 2014, 122: 775-786. PMID: 24896072, PMCID: PMC4123031, DOI: 10.1289/ehp.1307728.Peer-Reviewed Original ResearchConceptsEffects of BPAAnimal modelsGerm cell nest breakdownAdverse birth outcomesBisphenol A (BPA) exposureMultiple animal modelsReproductive health outcomesFemale reproductionImpact of BPAMale reproductive systemReproductive end pointsOvarian toxicantsEndometrial proliferationBirth outcomesAlters steroidogenesisImplantation failureA ExposureSexual dysfunctionBPA exposureUterine receptivityHuman evidenceBPA actionPubMed searchAnimal studiesInsufficient evidence
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply