2023
Typhoid fever
Meiring J, Khanam F, Basnyat B, Charles R, Crump J, Debellut F, Holt K, Kariuki S, Mugisha E, Neuzil K, Parry C, Pitzer V, Pollard A, Qadri F, Gordon M. Typhoid fever. Nature Reviews Disease Primers 2023, 9: 71. PMID: 38097589, DOI: 10.1038/s41572-023-00480-z.Peer-Reviewed Original ResearchConceptsTyphoid feverUndifferentiated febrile illnessInvasive bacterial diseaseEffective vaccination programsFecal-oral routeNovel diagnostic modalitiesFebrile illnessBloodstream infectionsVaccination programBlood culturesClinical trialsImmunological protectionHigh burdenCausative organismDiagnostic modalitiesGlobal burdenDisease pathogenesisFeverHuman infectionsIntestinal epitheliumYoung adultsCulture testingSalmonella enterica subspSerovar TyphiAntimicrobial resistance
2022
Etiologies of Acute Undifferentiated Febrile Illnesses in and near Iquitos from 1993 to 1999 in the Amazon River Basin of Peru
Watts DM, Russell KL, Wooster MT, Sharp TW, Morrison AC, Kochel TJ, Bautista CT, Block K, Guevara C, Aguilar P, Palermo PM, Calampa C, Porter KR, Hayes CG, Weaver SC, de Rosa AT, Vinetz JM, Shope RE, Gotuzzo E, Guzman H, Tesh RB. Etiologies of Acute Undifferentiated Febrile Illnesses in and near Iquitos from 1993 to 1999 in the Amazon River Basin of Peru. American Journal Of Tropical Medicine And Hygiene 2022, 107: 1114-1128. PMID: 36162442, PMCID: PMC9709010, DOI: 10.4269/ajtmh.22-0259.Peer-Reviewed Original ResearchConceptsFebrile illnessAcute undifferentiated febrile illnessUndifferentiated febrile illnessFebrile patientsAcute leptospirosisFebrile casesAsymptomatic infectionIgG antibodiesHealth burdenHealth clinicsClinical dataBlood samplesMicroscopic agglutinationDengue virusPatientsEncephalitis virusBlood smearsHuman morbidityLeptospira sppMalariaFurther studiesArbovirusesHealth impactsBaseline knowledgeEtiologyFrequency and Geographic Distribution of Borrelia miyamotoi, Borrelia burgdorferi, and Babesia microti Infections in New England Residents.
Johnston D, Kelly JR, Ledizet M, Lavoie N, Smith RP, Parsonnet J, Schwab J, Stratidis J, Espich S, Lee G, Maciejewski KR, Deng Y, Majam V, Zheng H, Bonkoungou SN, Stevens J, Kumar S, Krause PJ. Frequency and Geographic Distribution of Borrelia miyamotoi, Borrelia burgdorferi, and Babesia microti Infections in New England Residents. Clinical Infectious Diseases 2022 PMID: 35325084, DOI: 10.1093/cid/ciac107.Peer-Reviewed Original ResearchBabesia microti infectionB. miyamotoiMicroti infectionB. burgdorferiB. microtiAcute undifferentiated febrile illnessCross-sectional seroprevalence studyBorrelia miyamotoiUndifferentiated febrile illnessB. miyamotoi infectionBorrelia burgdorferiLevel of seroprevalenceIxodes scapularis ticksFebrile illnessTickborne infectionMiyamotoi infectionSeroprevalence studyHuman infectionsIxodes pacificus ticksClinical casesInfectionSerum samplesAverage seroprevalenceSpecific antibodiesScapularis ticks
2015
Molecular Characterisation of Chikungunya Virus Infections in Trinidad and Comparison of Clinical and Laboratory Features with Dengue and Other Acute Febrile Cases
Sahadeo N, Mohammed H, Allicock O, Auguste A, Widen S, Badal K, Pulchan K, Foster J, Weaver S, Carrington C. Molecular Characterisation of Chikungunya Virus Infections in Trinidad and Comparison of Clinical and Laboratory Features with Dengue and Other Acute Febrile Cases. PLOS Neglected Tropical Diseases 2015, 9: e0004199. PMID: 26580074, PMCID: PMC4651505, DOI: 10.1371/journal.pntd.0004199.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overChikungunya FeverChikungunya virusDengueDiagnosis, DifferentialFemaleFever of Unknown OriginGenotypeHumansMaleMiddle AgedMolecular Diagnostic TechniquesMolecular Sequence DataPhylogenyRNA, ViralSequence Analysis, DNASequence HomologyTrinidad and TobagoYoung AdultConceptsAcute undifferentiated febrile illnessChikungunya feverChikungunya virusCHIKV infectionDengue virusDengue feverRT-qPCRExact testLower white blood cell countWhite blood cell countPearson χ2Undifferentiated febrile illnessCharacteristics of patientsChikungunya virus infectionSymptoms of peopleBlood cell countComparison of ClinicalConfidence intervalsFisher's exact testT-testStudent's t-testMann-Whitney UFebrile illnessJoint painLaboratory features
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