2024
The Impact of Medical Comorbidities on Cough Improvement Following Superior Laryngeal Block
Shah R, Wilkins S, Malik D, Kohli N. The Impact of Medical Comorbidities on Cough Improvement Following Superior Laryngeal Block. Annals Of Otology Rhinology & Laryngology 2024, 133: 519-523. PMID: 38375777, DOI: 10.1177/00034894241231375.Peer-Reviewed Original ResearchChronic refractory coughCough Severity IndexRefractory coughTreatment of chronic coughTreatment of chronic refractory coughHistory of GERDVocal fold paresisSuperior laryngeal nerveCough improvementPatient's comorbidity profilePulmonary historyImpact of medical comorbidityLaryngeal hypersensitivityPatient demographicsUnclear etiologySmoking historyPulmonary conditionsChronic coughLung pathologyPatient counselingCough lastingLaryngeal nerveLaryngology clinicTreatment efficacyBlockade
2022
Noninvasive biomarkers for the diagnosis and management of autoimmune hepatitis
Harrington C, Krishnan S, Mack CL, Cravedi P, Assis DN, Levitsky J. Noninvasive biomarkers for the diagnosis and management of autoimmune hepatitis. Hepatology 2022, 76: 1862-1879. PMID: 35611859, PMCID: PMC9796683, DOI: 10.1002/hep.32591.Peer-Reviewed Original ResearchConceptsAutoimmune hepatitisNormal serum transaminasesPediatric autoimmune hepatitisFirst-line treatmentAcute liver failureImmune cell phenotypesPredictors of responseHigh clinical valueNovel candidate biomarkersPersonalized therapeutic managementSystemic corticosteroidsCurrent regimensMedication titrationHistological activityMost patientsClinical courseLiver failureLiver injurySerum transaminasesMedication dosingTherapeutic managementUnclear etiologyHepatic fibrosisClinical valueElevated riskActivated phosphoinositide 3-kinase δ syndrome associated with nephromegaly, growth hormone deficiency, bronchiectasis: a case report
Craig M, Geng B, Wigby K, Phillips S, Bakhoum C, Naheedy J, Cernelc-Kohan M. Activated phosphoinositide 3-kinase δ syndrome associated with nephromegaly, growth hormone deficiency, bronchiectasis: a case report. Allergy, Asthma & Clinical Immunology 2022, 18: 15. PMID: 35189965, PMCID: PMC8862239, DOI: 10.1186/s13223-022-00655-5.Peer-Reviewed Original ResearchGrowth hormone deficiencyHormone deficiencyPI3K pathwayAnatomic abnormalitiesUnique presentationOligoarticular juvenile idiopathic arthritisCase presentationThe patientK pathwayPatient's unique presentationJuvenile idiopathic arthritisUnique clinical featuresNine-year-old boyYears of ageMild developmental delayWhole-exome sequencingMultidisciplinary collaborative approachImmune cytopeniasHip painMicroscopic hematuriaRecurrent sinusitisBilateral nephromegalyGH therapyIdiopathic arthritisClinical featuresUnclear etiologyMetagenomic sequencing of the bronchoalveolar lavage extracellular virome and cellular transcriptome of sarcoidosis patients does not detect rubella virus
Keeler E, Vukmirovic M, Yan X, Gulino K, Ghedin E, Kaminski N, Sullivan K, Bushman F, Collman R, Rosenbach M. Metagenomic sequencing of the bronchoalveolar lavage extracellular virome and cellular transcriptome of sarcoidosis patients does not detect rubella virus. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases 2022, 39: e2022040. PMID: 36533601, PMCID: PMC9798337, DOI: 10.36141/svdld.v39i4.13407.Peer-Reviewed Original ResearchSarcoidosis patientsRubella virusBronchoalveolar lavageMultisystem granulomatous inflammatory diseaseImmune-competent patientsRubella virus infectionGranulomatous inflammatory diseaseCutaneous sarcoidosisAntigenic triggerBAL cellsUnclear etiologyRubella virus genomeInflammatory diseasesCutaneous granulomasGranulomatous lesionsVirus infectionVirus gene expressionLung samplesAcellular fluidCompetent patientsPatientsSarcoidosisOverlapping featuresMetagenomic sequencingVirus
2019
Recessive Mutations in KIF12 Cause High Gamma‐Glutamyltransferase Cholestasis
Aksu A, Das SK, Nelson‐Williams C, Jain D, Hoşnut F, Şahin G, Lifton RP, Vilarinho S. Recessive Mutations in KIF12 Cause High Gamma‐Glutamyltransferase Cholestasis. Hepatology Communications 2019, 3: 471-477. PMID: 30976738, PMCID: PMC6442693, DOI: 10.1002/hep4.1320.Peer-Reviewed Original ResearchLiver diseaseHigh GGTUndiagnosed liver diseaseHomozygous mutationCholestatic liver diseaseUnmet medical needWhole-exome sequencingSame homozygous mutationPediatric hepatologyNeonatal cholestasisRare homozygous mutationUnclear etiologyCholestasisUndiagnosed childrenMedical needUnrelated childrenGermline DNADiseaseMember 12ChildrenConsanguineous unionsOlder siblingsMissense mutationsGGTDamaging mutations
2018
Sera From Children After Cardiopulmonary Bypass Reduces Permeability of Capillary Endothelial Cell Barriers
Pierce RW, Zahr RA, Kandil S, Faustino EVS, Pober JS. Sera From Children After Cardiopulmonary Bypass Reduces Permeability of Capillary Endothelial Cell Barriers. Pediatric Critical Care Medicine 2018, 19: 609-618. PMID: 29652749, PMCID: PMC6037548, DOI: 10.1097/pcc.0000000000001553.Peer-Reviewed Original ResearchConceptsTransendothelial electrical resistanceCardiopulmonary bypassCapillary endothelial cellsEndothelial cellsCapillary leakPatient seraClaudin-5Pulmonary capillary endothelial cellsBarrier functionPulmonary microvascular endothelial cellsReal-time quantitative reverse transcription polymerase chain reactionTertiary pediatric hospitalQuantitative reverse transcription polymerase chain reactionCardiopulmonary bypass circuitCongenital heart diseaseReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionMicrovascular endothelial cellsEndothelial cell barrierCohort studyInflammatory mediatorsPediatric hospitalUnclear etiologyBarrier disruptionHeart disease
2012
Respecting Symptoms in Thoracic Aortic Aneurysm Management: A Case of Symptomatic Necrotizing Granulomatous Aortitis
Kuzmik G, Sang A, Cai G, Tranquilli M, Elefteriades J. Respecting Symptoms in Thoracic Aortic Aneurysm Management: A Case of Symptomatic Necrotizing Granulomatous Aortitis. International Journal Of Angiology 2012, 21: 151-154. PMID: 23997559, PMCID: PMC3578625, DOI: 10.1055/s-0032-1315632.Peer-Reviewed Case Reports and Technical NotesAortic aneurysm managementComputed tomography angiographyThoracic aortic aneurysmInterventional criteriaChest painAortic pathologyAortic ruptureNoninfectious etiologiesRadiographic evidenceUnclear etiologyAortic aneurysmTomography angiographyGranulomatous aortitisSurgical decisionAneurysm managementOperating roomAortitisIrregular contoursAneurysmsAortaEtiologySymptomsImminent riskRupturePain
2010
Fibromyalgia, Arthritic, and Myofascial Pain
Vadivelu N, Urman R. Fibromyalgia, Arthritic, and Myofascial Pain. 2010, 557-566. DOI: 10.1007/978-0-387-87579-8_25.Chapters
1998
Acid-base Homeostasis in Children With Growth Hormone Deficiency
Glaser N, Shirali A, Styne D, Jones K. Acid-base Homeostasis in Children With Growth Hormone Deficiency. 1998, 102: 1407-1414. PMID: 9832577, DOI: 10.1542/peds.102.6.1407.Peer-Reviewed Original ResearchConceptsMean serum bicarbonate concentrationSerum bicarbonate concentrationGrowth hormone deficiencyStandard deviation scoreGH treatmentShort statureGrowth hormoneAcid-base homeostasisHormone deficiencyBicarbonate concentrationLower serum bicarbonate concentrationMild metabolic acidosisSerum electrolyte concentrationsNormal acid-base homeostasisCause of acidosisRenal functionUnclear etiologyMetabolic acidosisMedical recordsOverall prevalenceGrowth failureDeviation scoreStudy populationPatientsIntermediate probability
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply