2025
PTEN inactivating mutations are associated with hormone receptor loss during breast cancer recurrence
Zhan H, Antony V, Tang H, Theriot J, Liang Y, Hui P, Krishnamurti U, DiGiovanna M. PTEN inactivating mutations are associated with hormone receptor loss during breast cancer recurrence. Breast Cancer Research And Treatment 2025, 211: 441-447. PMID: 40063317, DOI: 10.1007/s10549-025-07660-3.Peer-Reviewed Original ResearchConceptsPten inactivating mutationsBreast cancerER+/HER2- tumorsRecurrent tumorsER+/HER2- breast cancer patientsInactivating mutationsAssociated with worse clinical outcomesTreatment historyER+/HER2- breast cancerTriple negative phenotypeBreast cancer recurrenceBreast cancer patientsHormone receptor lossResultsThe average timeHR+ tumorsDistant recurrenceHR statusER expressionRecurrent diseaseTumor histologyTumor recurrenceHER2 expressionHormone independencePatient ageClinicopathological characteristics
2024
Development and preliminary validation of a platform for systematic, unbiased pre-screening of non-small cell lung cancer (NSCLC) across three community oncology practices.
Campbell Fontaine A, McAneny B, Tucker V, Koontz M, Trotter C, Paulson J, Svedman C, Pan A, Peguero J, Campos L. Development and preliminary validation of a platform for systematic, unbiased pre-screening of non-small cell lung cancer (NSCLC) across three community oncology practices. Journal Of Clinical Oncology 2024, 42: e23230-e23230. DOI: 10.1200/jco.2024.42.16_suppl.e23230.Peer-Reviewed Original ResearchNon-small cell lung cancerClinical trialsCommunity oncology practicesMedical oncologistsNon-small cell lung cancer ptsOncology practiceCell lung cancerClinical trial patient populationTrial patient populationTesting ratesPre-screening of patientsIdentification of eligible patientsAssessment of eligibilityECOG PSClinical trial sitesMetastatic statusEligible patientsLung cancerRoutine clinical workflowPatient populationOncology patientsPatientsOncologist assessmentGold standardTreatment history
2020
Six Gynecological Cancer Patients Infected With SARS-CoV-2 After Surgery or Radio-/Chemo-Therapy Treatment: Case Series
Liu C, Huang Y, Qin T, Guo E, Wu P, Sun C, Chen G. Six Gynecological Cancer Patients Infected With SARS-CoV-2 After Surgery or Radio-/Chemo-Therapy Treatment: Case Series. Frontiers In Oncology 2020, 10: 1606. PMID: 33042803, PMCID: PMC7522534, DOI: 10.3389/fonc.2020.01606.Peer-Reviewed Original ResearchTreatment of gynecological cancer patientsGynecologic cancer patientsCancer patientsSARS-CoV-2History of cancer treatmentTreatment historyLow immune stateRaised white blood cellNosocomial SARS-CoV-2 infectionDifficulty of diagnosisCancer treatment historySARS-CoV-2 infectionWhite blood cellsDiagnosis of COVID-19Symptoms of COVID-19Antiviral treatmentAtypical symptomsAuxiliary examinationsTongji HospitalTreatment of COVID-19Treatment planningImmune stateCancer-related treatmentPatientsCancer treatment
2019
Recategorization of psoriasis severity: Delphi consensus from the International Psoriasis Council
Strober B, Ryan C, van de Kerkhof P, van der Walt J, Kimball A, Barker J, Blauvelt A, Members and Councilors I, Bourcier M, Carvalho A, Cohen A, Foley P, Evans C, Gisondi P, Griffiths C, El-Sayed M, Eschevarria C, Finlay A, Kalb R, Leonardi C, Lynde C, Murphy R, Murakami M, Okubo Y, Prens E, Puig L, Seyger M, Skov L, Terui T, Valenzuela F, Ward N, Wu J, Zheng M. Recategorization of psoriasis severity: Delphi consensus from the International Psoriasis Council. Journal Of The American Academy Of Dermatology 2019, 82: 117-122. PMID: 31425723, DOI: 10.1016/j.jaad.2019.08.026.Peer-Reviewed Original ResearchConceptsPsoriasis severityInternational Psoriasis CouncilSystemic therapyTopical therapyConsensus statementUndertreatment of psoriasisBody surface areaPast treatment historyPsoriasis involvementPsoriasis patientsClinical studiesTreatment decisionsDelphi consensusEligibility criteriaTreatment historyPatientsSevere categoryTherapySeverity categoriesSeverity definitionsSeverityDichotomous definitionSeverity classificationDelphi approachUndertreatmentAnalysis of the Impact of Antiretroviral Drug Changes on Survival of Patients with Advanced-Stage AIDS with Multidrug-Resistant HIV Infection
Ma R, Jung TH, Peduzzi PN, Brown ST, Kyriakides TC. Analysis of the Impact of Antiretroviral Drug Changes on Survival of Patients with Advanced-Stage AIDS with Multidrug-Resistant HIV Infection. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2019, 18: 2325958219849101. PMID: 31272313, PMCID: PMC6748500, DOI: 10.1177/2325958219849101.Peer-Reviewed Original ResearchConceptsDrug changesCox proportional hazards regression modelKaplan-Meier survival techniqueMultidrug-resistant HIV infectionProportional hazards regression modelsAdvanced-stage AIDSDrug regimen changesSurvival of patientsHazards regression modelsAntiretroviral clinical trialsClinical biomarker dataCause mortalityMedication changesARV regimenHIV infectionImproved survivalRegimen changeClinical outcomesNonclinical reasonsClinical trialsBiomarker changesTreatment historyMultidrug resistanceTherapy strategiesPatients
2018
Prospective analysis of somatic and germline genetic alterations in patients with ampullary carcinomas.
Wong W, O'Reilly E, Varghese A, Yu K, Iacobuzio-Donahue C, Shia J, Klimstra D, Allen P, Lowery M. Prospective analysis of somatic and germline genetic alterations in patients with ampullary carcinomas. Journal Of Clinical Oncology 2018, 36: 308-308. DOI: 10.1200/jco.2018.36.4_suppl.308.Peer-Reviewed Original ResearchSomatic genetic testingAmpullary carcinomaGermline alterationsSomatic alterationsMSK-IMPACTFamily history of cancerRare gastrointestinal cancerTargetable somatic alterationsGermline genetic alterationsHistory of cancerOpt-in strategyMedian ageClinicopathological featuresClinical historyGenetic alterationsFamily historySubgroup analysisGastrointestinal cancerMultiple genesGenetic testingProspective analysisScreening implicationsTreatment historyPatientsGenes
2015
Responses of adults who stutter to the anticipation of stuttering
Jackson E, Yaruss J, Quesal R, Terranova V, Whalen D. Responses of adults who stutter to the anticipation of stuttering. Journal Of Fluency Disorders 2015, 45: 38-51. PMID: 26065618, PMCID: PMC4728710, DOI: 10.1016/j.jfludis.2015.05.002.Peer-Reviewed Original ResearchConceptsAnticipation of stutteringResponses to anticipationSpeech production processSelf-report evidenceAnalysis of written responsesMeasuring anticipationStuttering severityStuttering behaviorRating ScaleStutteringSelf-management strategiesLikert rating scaleTreatment historyResponses of adultsAnticipationAdultsParticipantsPeople
2013
Validation of an algorithm to identify antiretroviral‐naïve status at time of entry into a large, observational cohort of HIV‐infected patients
Gandhi NR, Tate JP, Rodriguez‐Barradas M, Rimland D, Goetz MB, Gibert C, Brown ST, Mattocks K, Justice AC. Validation of an algorithm to identify antiretroviral‐naïve status at time of entry into a large, observational cohort of HIV‐infected patients. Pharmacoepidemiology And Drug Safety 2013, 22: 1019-1025. PMID: 23836591, PMCID: PMC3831617, DOI: 10.1002/pds.3476.Peer-Reviewed Original ResearchConceptsART-naïve patientsViral load thresholdMedical record reviewAntiretroviral treatmentMedical recordsHIV cohortObservational cohortRecord reviewVeterans Aging Cohort Study Virtual CohortVirtual cohortPrevious antiretroviral treatmentLaboratory dataPatients' medical recordsPositive predictive value 87Cohort entryAdverse eventsHIV outcomesRandomized trialsRetrospective studyAdverse reactionsTime of entryCopies/ART treatmentTreatment statusTreatment history
2011
Commentary: Jail-based competency restoration.
Kapoor R. Commentary: Jail-based competency restoration. The Journal Of The American Academy Of Psychiatry And The Law 2011, 39: 311-5. PMID: 21908746.Peer-Reviewed Original ResearchConceptsImpact of treatmentRestoration of competenceTreatment historyMental illnessInvoluntary medication
2009
Low-Abundance HIV Drug-Resistant Viral Variants in Treatment-Experienced Persons Correlate with Historical Antiretroviral Use
Le T, Chiarella J, Simen BB, Hanczaruk B, Egholm M, Landry ML, Dieckhaus K, Rosen MI, Kozal MJ. Low-Abundance HIV Drug-Resistant Viral Variants in Treatment-Experienced Persons Correlate with Historical Antiretroviral Use. PLOS ONE 2009, 4: e6079. PMID: 19562031, PMCID: PMC2698118, DOI: 10.1371/journal.pone.0006079.Peer-Reviewed Original ResearchConceptsAntiretroviral treatment historyDrug-resistant mutationsVirologic failureAntiretroviral useDrug-resistant variantsTreatment historyOverall burdenGenotypic resistanceHIV drug-resistant mutationsHIV drug-resistant variantsStanford HIV database algorithmDrug-resistant viral variantsSubsequent antiretroviral regimensTreatment-experienced patientsConventional genotypingPrior treatment historyUltra-deep pyrosequencingSanger sequencingAntiretroviral regimensMore antiretroviralsChart reviewAntiretroviral drugsUltra-deep sequencingClinical implicationsViral variants
2007
Patient Satisfaction with Primary Care Office-Based Buprenorphine/Naloxone Treatment
Barry DT, Moore BA, Pantalon MV, Chawarski MC, Sullivan LE, O’Connor P, Schottenfeld RS, Fiellin DA. Patient Satisfaction with Primary Care Office-Based Buprenorphine/Naloxone Treatment. Journal Of General Internal Medicine 2007, 22: 242-245. PMID: 17356993, PMCID: PMC1824745, DOI: 10.1007/s11606-006-0050-y.Peer-Reviewed Original ResearchConceptsBuprenorphine/naloxonePatient satisfactionBuprenorphine/naloxone treatmentDrug treatment historyOpioid-dependent patientsPrimary care officesOpioid-dependent subjectsSubstance use statusOverall satisfaction scoreOffice visit frequencyNaloxone treatmentParticipantsOne hundredPrimary outcomeCare officesFemale genderTreatment historyPatientsNaloxoneSatisfaction scoresEthnicity/raceTreatment locationUse statusVisit frequencyMedicationsTreatment
2002
SUICIDAL IDEATION AND SUICIDE ATTEMPTS IN TREATMENT-SEEKING PATHOLOGICAL GAMBLERS
PETRY N, KILUK B. SUICIDAL IDEATION AND SUICIDE ATTEMPTS IN TREATMENT-SEEKING PATHOLOGICAL GAMBLERS. The Journal Of Nervous And Mental Disease 2002, 190: 462-469. PMID: 12142848, PMCID: PMC3397475, DOI: 10.1097/00005053-200207000-00007.Peer-Reviewed Original ResearchConceptsSuicidal ideationSuicide attemptsSocial/familyPathological gamblersMore psychiatric symptomsAddiction Severity IndexSubstance abuse treatment historySouth Oaks Gambling Screen scoresTerms of severityPsychiatric symptomsTreatment historyTreatment programGreater cravingScreen scoresSuicide attemptersMore daysSeverity IndexFocused treatmentIdeationTreatment sitesPathological gamblingSouth Oaks Gambling ScreenTreatmentHigh rateLiving situations
1997
Syphilis Serology in Human Immunodeficiency Virus Infection: Evidence for False-Negative Fluorescent Treponemal Testing
Erbelding E, Vlahov D, Nelson K, Rompalo A, Cohn S, Sanchez P, Quinn T, Brathwaite W, Thomas D. Syphilis Serology in Human Immunodeficiency Virus Infection: Evidence for False-Negative Fluorescent Treponemal Testing. The Journal Of Infectious Diseases 1997, 176: 1397-1400. PMID: 9359747, DOI: 10.1086/517330.Peer-Reviewed Original ResearchConceptsFTA-ABS testHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionBFP reactionsVirus infectionRapid plasma reagin titerFluorescent treponemal antibody absorption testInjection drug usersAntibody absorption testPresence of antibodiesTreponema pallidum antigensFalse positive reactorsBFP reactorsSyphilis serologySerologic patternTreatment historyDrug usersMembrane antigenTreponemal testingAntigenNegative resultsSyphilisInfectionAntibodiesSerology
1985
Chronic pain: A multiple-setting comparison of patient characteristics
Holzman A, Rudy T, Gerber K, Turk D, Sanders S, Zimmerman J, Kerns R. Chronic pain: A multiple-setting comparison of patient characteristics. Journal Of Behavioral Medicine 1985, 8: 411-422. PMID: 4093976, DOI: 10.1007/bf00848372.Peer-Reviewed Original ResearchConceptsHospital programTreatment historyChronic pain patientsPain management programPain symptomsPatient agePatient characteristicsPain patientsPain programPain problemsOptimal treatmentGeneral hospital programsPain variablesTreatment outcomesDisability compensationAgePatientsSymptomsManagement programMultiple variablesDemographics
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