2024
Poly(butylene succinate) reinforced by small amount of grafted nanofibrillated bacterial cellulose: Toughness variability based on nanocomposites preparation method
Hashim H, Xia X, Kani H, Seno S, Li F, Isono T, Yamamoto T, Tani H, Satoh T, Tajima K. Poly(butylene succinate) reinforced by small amount of grafted nanofibrillated bacterial cellulose: Toughness variability based on nanocomposites preparation method. Composites Part A Applied Science And Manufacturing 2024, 185: 108341. DOI: 10.1016/j.compositesa.2024.108341.Peer-Reviewed Original ResearchMelt-kneadedNanofibrillated bacterial cellulosePolybutylene succinateSolvent castingHydroxypropyl celluloseNanocomposite preparation methodBacterial celluloseLow mechanical performanceMechanical performanceFlexural strengthPoly(butylene succinateReinforcing agentYoung's modulusNanocompositesBiodegradable polymersToughnessCompost biodegradation testsSurface compatibilityBiodegradation testsModulusPreparation methodDispersing agentHydrophobic moietiesCellulose-producing bacteriumCellulose
2021
Abluminal groove-filled biodegradable polymer sirolimus-eluting stent versus durable polymer everolimus-eluting stent: three-year results of the TARGET All Comers trial.
Saito Y, Kelbæk H, Xu B, Hussain Y, Anderson R, Schächinger V, Zheng M, Wijns W, Baumbach A, Lansky AJ. Abluminal groove-filled biodegradable polymer sirolimus-eluting stent versus durable polymer everolimus-eluting stent: three-year results of the TARGET All Comers trial. EuroIntervention 2021, 17: e332-e334. PMID: 32482617, PMCID: PMC9724996, DOI: 10.4244/eij-d-20-00344.Peer-Reviewed Original Research
2017
INTRAVASCULAR IMAGING COMPARISON OF TWO METALLIC LIMUS-ELUTING STENTS ABLUMINALLY COATED WITH BIODEGRADABLE POLYMERS: IVUS AND OCT RESULTS OF THE DESTINY TRIAL
de Ribamar Costa J, Chamie D, Abizaid A, Ribeiro E, Meireles G, Prudente M, Costa R, Lemos P. INTRAVASCULAR IMAGING COMPARISON OF TWO METALLIC LIMUS-ELUTING STENTS ABLUMINALLY COATED WITH BIODEGRADABLE POLYMERS: IVUS AND OCT RESULTS OF THE DESTINY TRIAL. Journal Of The American College Of Cardiology 2017, 69: 1108. DOI: 10.1016/s0735-1097(17)34497-2.Peer-Reviewed Original Research
2016
Intravascular imaging comparison of two metallic limus-eluting stents abluminally coated with biodegradable polymers: IVUS and OCT results of the DESTINY trial
Costa J, Chamié D, Abizaid A, Ribeiro E, Meireles G, Prudente M, Campos C, Castro J, Costa R, Lemos P. Intravascular imaging comparison of two metallic limus-eluting stents abluminally coated with biodegradable polymers: IVUS and OCT results of the DESTINY trial. The International Journal Of Cardiovascular Imaging 2016, 33: 161-168. PMID: 27714601, DOI: 10.1007/s10554-016-0992-z.Peer-Reviewed Original ResearchMeSH KeywordsAbsorbable ImplantsCardiovascular AgentsCoronary Artery DiseaseCoronary VesselsDrug-Eluting StentsHumansMetalsNeointimaPercutaneous Coronary InterventionPolymersPredictive Value of TestsProsthesis DesignSirolimusTime FactorsTomography, Optical CoherenceTreatment OutcomeUltrasonography, Interventional
2015
Biodegradable DNA Nanoparticles that Provide Widespread Gene Delivery in the Brain
Mastorakos P, Song E, Zhang C, Berry S, Park H, Kim Y, Park J, Lee S, Suk J, Hanes J. Biodegradable DNA Nanoparticles that Provide Widespread Gene Delivery in the Brain. Small 2015, 12: 678-685. PMID: 26680637, PMCID: PMC4913277, DOI: 10.1002/smll.201502554.Peer-Reviewed Original ResearchConceptsDNA nanoparticlesHigh-level transgene expressionTransgene expressionGene delivery platformSuccessful gene therapyConventional gene vectorsBrain-penetrating nanoparticlesPolyethylene glycol (PEG) coronaWidespread gene deliveryNanoparticle platformGene deliveryGene vectorsNanoparticlesDelivery platformGene therapyStable subTransgene expression patternsBiodegradable polymersConvection-enhanced deliveryPressure-driven flowDeliveryPlatformExtracellular matrixPromiseSteric hindranceHighly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy
Mastorakos P, da Silva A, Chisholm J, Song E, Choi W, Boyle M, Morales M, Hanes J, Suk J. Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: 8720-8725. PMID: 26124127, PMCID: PMC4507234, DOI: 10.1073/pnas.1502281112.Peer-Reviewed Original ResearchConceptsHigh-level transgene expressionGene delivery systemsDNA nanoparticlesTransgene expressionNanoparticle-based gene delivery systemGene therapyDelivery systemLung gene therapyRobust transgene expressionTherapeutic genesTransfection efficiencyColloidal stabilityNanoparticlesBiological barriersTunable platformPhysiological fluidsBiodegradable polymersDense coronaConventional therapeuticsMucus barrierPolyethylene glycolMucus gel layerTreatment of diseasesSignificant hurdlePBAE
2009
Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency
Cu Y, LeMoëllic C, Caplan MJ, Saltzman WM. Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency. Nanomedicine Nanotechnology Biology And Medicine 2009, 6: 334-343. PMID: 19800989, PMCID: PMC2847641, DOI: 10.1016/j.nano.2009.09.001.Peer-Reviewed Original ResearchConceptsTransfection efficiencyDNA deliveryDNA release rateParticle carriersUnmodified particlesCLINICAL EDITORDrug carriersGene carriersPayload releaseBovine serum albuminCell uptakeParticle surfaceDNA releasePolymer drug carriersPLGASpecific cellsBiodegradable polymersCarriersSerum albuminRelease rateBSAParticlesHigh densityHigh uptakeDelivery
2005
Artificial blood vessel: The Holy Grail of peripheral vascular surgery
Kakisis JD, Liapis CD, Breuer C, Sumpio BE. Artificial blood vessel: The Holy Grail of peripheral vascular surgery. Journal Of Vascular Surgery 2005, 41: 349-354. PMID: 15768021, DOI: 10.1016/j.jvs.2004.12.026.Peer-Reviewed Original ResearchConceptsVascular tissue engineeringArtificial vesselsIdeal vascular graftMechanical propertiesArtificial blood vesselsTissue engineeringBiodegradable polymersNative tissuePulsatile flowSmall intestine submucosaVascular graftsVivo environmentBioreactorVascular cellsPeripheral vascular surgeryInitial experimentsEngineeringPolymersFlow
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