2018
Impaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis
Proudfoot M, van Ede F, Quinn A, Colclough G, Wuu J, Talbot K, Benatar M, Woolrich M, Nobre A, Turner M. Impaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis. Clinical Neurophysiology 2018, 129: 1479-1489. PMID: 29678369, DOI: 10.1016/j.clinph.2018.03.019.Peer-Reviewed Original ResearchConceptsALS patientsHealthy controlsCorticomuscular coherenceGene carriersAsymptomatic gene carriersBeta-band corticomuscular coherenceMotor cortexTherapeutic efficacyDisease mimicsMotor system dysfunctionSystem dysfunctionWhole-head magnetoencephalographyPatientsForce productionNeuropathyPrimary motor cortexBeta rhythmsBeta bandCortical hemisphereStructural MRICortexNeural activityMuscular contractionInterhemispheric communicationCorticomuscular
2009
Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency
Cu Y, LeMoëllic C, Caplan MJ, Saltzman WM. Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency. Nanomedicine Nanotechnology Biology And Medicine 2009, 6: 334-343. PMID: 19800989, PMCID: PMC2847641, DOI: 10.1016/j.nano.2009.09.001.Peer-Reviewed Original ResearchConceptsTransfection efficiencyDNA deliveryDNA release rateParticle carriersUnmodified particlesCLINICAL EDITORDrug carriersGene carriersPayload releaseBovine serum albuminCell uptakeParticle surfaceDNA releasePolymer drug carriersPLGASpecific cellsBiodegradable polymersCarriersSerum albuminRelease rateBSAParticlesHigh densityHigh uptakeDelivery
2006
Clinical Performance of Original and Revised Bethesda Guidelines for the Identification of MSH2/MLH1 Gene Carriers in Patients with Newly Diagnosed Colorectal Cancer: Proposal of a New and Simpler Set of Recommendations
Rodríguez-Moranta F, Castells A, Andreu M, Piñol V, Castellví-Bel S, Alenda C, Llor X, Xicola RM, Jover R, Payá A, Bessa X, Balaguer F, Cubiella J, Argüello L, Morillas JD, Bujanda L. Clinical Performance of Original and Revised Bethesda Guidelines for the Identification of MSH2/MLH1 Gene Carriers in Patients with Newly Diagnosed Colorectal Cancer: Proposal of a New and Simpler Set of Recommendations. The American Journal Of Gastroenterology 2006, 101: ajg2006204. PMID: 16696788, DOI: 10.1111/j.1572-0241.2006.00522.x.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAgedCarrier ProteinsColorectal NeoplasmsEpidemiologic StudiesHeterozygoteHumansMiddle AgedMutationMutL Protein Homolog 1MutS Homolog 2 ProteinNuclear ProteinsPractice Guidelines as TopicPredictive Value of TestsProspective StudiesSensitivity and SpecificitySpainConceptsBethesda guidelinesColorectal cancerNegative predictive valuePredictive valueClinical performanceMLH1 germline mutationsGene mutation carriersLogistic regression analysisNational Cancer InstitutePositive predictive valueCancer genetic testingMutation carriersIdentification of individualsEpidemiology SurveysCancer InstitutePatientsGenetic testingGermline mutationsEPICOLON studyCancerOriginal guidelinesGene carriersRegression analysisGuidelinesTerms of sensitivity
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