2024
Computational analysis of heart valve growth and remodeling after the Ross procedure
Middendorp E, Braeu F, Baaijens F, Humphrey J, Cyron C, Loerakker S. Computational analysis of heart valve growth and remodeling after the Ross procedure. Biomechanics And Modeling In Mechanobiology 2024, 23: 1889-1907. PMID: 39269523, PMCID: PMC11554944, DOI: 10.1007/s10237-024-01874-y.Peer-Reviewed Original ResearchRoss procedureBlood pressure controlRoot dilatationHomogeneous mixture modelPatient's own pulmonary valveMechanical homeostasisPressure controlAortic heart valvesPublished clinical studiesConstrained mixture modelsHemodynamic environmentPulmonary autograftPulmonary valveLeaflet elongationPressure conditionsClinical studiesG&RHemodynamic loadTissue compositionValve growthTissue depositionMixture modelDilatationHeart valvesAutograftCell signaling and tissue remodeling in the pulmonary autograft after the Ross procedure: A computational study
Maes L, Vervenne T, Hendrickx A, Estrada A, Van Hoof L, Verbrugghe P, Rega F, Jones E, Humphrey J, Famaey N. Cell signaling and tissue remodeling in the pulmonary autograft after the Ross procedure: A computational study. Journal Of Biomechanics 2024, 171: 112180. PMID: 38906711, DOI: 10.1016/j.jbiomech.2024.112180.Peer-Reviewed Original ResearchRoss procedurePulmonary autograftPatient's pulmonary valveTranscription factorsPulmonary valveSmooth muscleActivation of genesAortic positionRelevant transcription factorsTissue remodelingAutograftExcessive dilatationTranscriptome dataGene activationCell signalingSignaling pathwayTarget genesMultiscale modelGenesTissueCellsFailure mechanismCell-scaleMechanical propertiesCell-scale model
2012
Outcomes of the infant Ross procedure for congenital aortic stenosis followed into adolescence
Elder RW, Quaegebeur JM, Bacha EA, Chen JM, Bourlon F, Williams IA. Outcomes of the infant Ross procedure for congenital aortic stenosis followed into adolescence. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: 1504-1511. PMID: 23062969, PMCID: PMC3657341, DOI: 10.1016/j.jtcvs.2012.09.004.Peer-Reviewed Original ResearchConceptsCongenital aortic stenosisRoss procedureLong-term outcomesAortic stenosisRight ventricular outflow tract reinterventionVentricular outflow tract reinterventionRight ventricular outflow tractSignificant aortic stenosisVentricular outflow tractAortic valve diseaseNew York-PresbyterianAvoidance of anticoagulationCatheter-based interventionsMonths of ageAutograft annulusAutograft growthAutograft reinterventionAortic insufficiencyLatest followMedian ageRetrospective reviewRoss operationCardiothoracic centreRecent followModerate dilatation
2005
Midterm Thromboembolic and Bleeding Complications are Minimal After Composite Graft Replacement of the Aortic Root
Hatzaras I, Koullias G, Tranquilli M, Achneck H, Elefteriades J. Midterm Thromboembolic and Bleeding Complications are Minimal After Composite Graft Replacement of the Aortic Root. International Journal Of Angiology 2005, 14: 118-122. DOI: 10.1007/s00547-005-2050-x.Peer-Reviewed Original ResearchComposite graft replacementGraft replacementAortic valveValve-sparing aortic root proceduresEight-year survivalSt. Jude groupWarfarin-related bleedingEvent-free survivalKaplan-Meier curvesMechanical valve conduitAortic root proceduresChronic aneurysmHospital mortalityINR 1.8Late thromboembolismPostdischarge survivalAcute typeBleeding complicationsHospital morbidityRoss procedurePostoperative followupConsecutive patientsLatest followupMidterm followupLate causesMidterm thromboembolic and bleeding complications are minimal after composite graft replacement of the aortic root
Hatzaras I, Koullias G, Tranquilli M, Achneck H, Elefteriades J. Midterm thromboembolic and bleeding complications are minimal after composite graft replacement of the aortic root. International Journal Of Angiology 2005, 118-122. DOI: 10.1055/s-0031-1276503.Peer-Reviewed Original ResearchComposite graft replacementGraft replacementAortic valveValve-sparing aortic root proceduresEight-year survivalSt. Jude groupWarfarin-related bleedingEvent-free survivalKaplan-Meier curvesMechanical valve conduitAortic root proceduresChronic aneurysmHospital mortalityINR 1.8Late thromboembolismPostdischarge survivalAcute typeHospital morbidityPostoperative followupRoss procedureConsecutive patientsLatest followupLate causesMean ageAortic root
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