2024
Human red blood cells express the RNA sensor TLR7
Metthew Lam L, Oatman E, Eckart K, Klingensmith N, Flowers E, Sayegh L, Yuen J, Clements R, Meyer N, Jurado K, Vaughan A, Eisenbarth S, Mangalmurti N. Human red blood cells express the RNA sensor TLR7. Scientific Reports 2024, 14: 15789. PMID: 38982195, PMCID: PMC11233670, DOI: 10.1038/s41598-024-66410-5.Peer-Reviewed Original Research
2004
Update on the clinical spectrum and genetics of red blood cell membrane disorders.
Gallagher PG. Update on the clinical spectrum and genetics of red blood cell membrane disorders. Current Hematology Reports 2004, 3: 85-91. PMID: 14965483.Peer-Reviewed Original ResearchConceptsStructure/function relationshipsSignificant genetic heterogeneityPrecise genetic defectGenetic lociMolecular biologyRed blood cell membrane disordersSplicing mutationGene deletionNonsense mutationCell membraneFunction relationshipsGenetic heterogeneityGenetic defectsHereditary elliptocytosisMembrane disordersRed blood cell membraneBlood cell membranesHereditary pyropoikilocytosisMutationsBetter understandingErythrocyte membranesMembraneLociGeneticsBiology
2000
Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3
Zhang D, Kiyatkin A, Bolin J, Low P. Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3. Blood 2000, 96: 2925-2933. DOI: 10.1182/blood.v96.9.2925.h8002925_2925_2933.Peer-Reviewed Original ResearchCytoplasmic domainP72syk protein tyrosine kinaseGlyceraldehyde-3-phosphate dehydrogenaseProtein-binding domainsGlyceraldehyde-3-phosphateProtein tyrosine kinasesAnimal cell plasma membranesCell plasma membraneCytoplasmic domain of erythrocyte membrane band 3Improved structure definitionBinding domainMultiple proteinsPeripheral proteinsProtein networkPlasma membraneOrganizing centerDimerization armTyrosine kinaseCdb3Protein ligandsBinding sitesConformational changesFunctional interpretationProteinRed blood cell membraneCrystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3
Zhang D, Kiyatkin A, Bolin J, Low P. Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3. Blood 2000, 96: 2925-2933. PMID: 11049968, DOI: 10.1182/blood.v96.9.2925.Peer-Reviewed Original ResearchConceptsCytoplasmic domainPeripheral proteinsAnimal cell plasma membranesRed blood cell membraneProtein tyrosine kinasesGlyceraldehyde-3-phosphate dehydrogenaseErythrocyte membrane band 3Major conformational changesMajor organizing centersCell plasma membraneBand 3Membrane band 3Protein 4.2Dimerization armProtein networkPlasma membraneMultiple proteinsTyrosine kinaseProtein ligandsOrganizing centerConformational changesImproved structural definitionCell membraneProtein 4Protein
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