iPSC Core

Welcome to the iPSC Core of the Yale ADRC.

The Yale ADRC seeks cell biological understanding of neural cell dysfunction in Alzheimer’s Disease (AD) with the long-term goal of identifying new targets for successful therapeutic intervention across population groups. Our iPSC Core seeks to promote cell biological studies using induced pluripotent stem cells (iPSC)-derived neural cells. This approach utilizes human cells to increase translational relevance and allows assessment across varied genetic backgrounds.

Our mission is to serve as a foundational resource for researchers and laboratories, enhancing the rigor and impact of scientific discoveries within the Neuroscience community at Yale. Through strong collaborations with principal investigators and their trainees, we aim to empower excellence in research and innovation.

The iPSC Core is co-led by Dr. Juliana Salgado and Dr. Tanina Arab, and is available to all members of the Yale Neuroscience Department, as well as Yale affiliates of the Ludwig Program and the Alzheimer’s Disease Research Center (ADRC).

The core is supported by the ADRC grant awarded to Dr. Stephen Strittmatter and Dr. In-Hyun Park, with the specific mission to:

• Manage the collection, characterization, storage, and sharing of iPSC lines;
• Distribute live differentiated cultures of human iPSC-derived neural cells for Alzheimer’s disease (AD) research.

We look forward to supporting your work and contributing to transformative progress in neuroscience. Please contact us for any questions ipscneurocore@yale.edu