Leading the Administrative Core are the Directors of the Yale ADRC, Stephen M. Strittmatter, MD, PhD, and Christopher H. van Dyck, MD. The Administrative Core provides leadership and coordination and oversees all Center activities. It emphasizes the use of proteomic studies for translational science to achieve a goal of understanding the cellular basis of Alzheimer’s disease and translating this knowledge into effective therapy.
Alzheimer's Disease Research Center Cores
The Yale Alzheimer’s Disease Research Center (ADRC) seeks to advance our understanding of Alzheimer’s disease at a cell biological level with the eventual goal of translating laboratory discoveries into novel effective clinical therapies. It includes eight Cores (Administrative Core, Clinical Core, Data Management and Statistics Core, Biomarker Core, Neuropathology Core, Imaging Core, Outreach, Recruitment and Engagement Core, and Research Education Core), which will work together to achieve this goal.
Alzheimer's Disease Research Center Cores
Administrative Core Clinical Core Led by Drs. Christopher H. van Dyck, MD and Adam Mecca, MD, the Clinical Core aims to perform research diagnostic evaluations for a large clinical population.Data Management and Statistics Core The Data Management and Statistics Core (DMSC) provides data management and statistical support to meet operational and research needs. It interacts with other Yale ADRC Cores to manage and integrate metadata/data and provide statistical consultation on design and analysis of studies and educational and outreach program evaluation. The DMSC created and maintains data management and biorepository systems and procedures for subject tracking, accrual, and other conduct of study reports. The Data Management and Statistics Core ensures patient data confidentiality and protection through secure, HIPAA-compliant data management systems and practices.Imaging and Biomarker Core The Yale Alzheimer’s Disease Research Center (ADRC) seeks to advance our understanding of Alzheimer’s disease at a cell biological level with the goal of translating laboratory discoveries into novel effective clinical therapies.
iPSC Core Neuropathology Core The Neuropathology Core is co-led by Drs. Anita Huttner MD, Director of Neuropathology, Pathology, and Caroline Zeiss PhD, Chief of Pathology, Comparative Medicine, and fulfills multiple important roles within the Yale Alzheimer's Disease Research Center (ADRC).Outreach, Recruitment and Engagement Core Through communication with the general public, healthcare professionals, and service providers, the Outreach, Recruitment and Engagement Core (ORE) assists the Clinical Core with the recruitment of a clinical population.
Research and Education Core The overall objective of the Yale ADRC Research Education Core (REC) is to serve as an institutional hub for all educational, didactic, and career development activities aimed at promoting future leaders that will bridge clinical and basic sciences to improve clinical outcomes and quality of life of individuals with dementing disorders.