Zyad James Carr, MD

• Adriana Dana Oprea
• Jill Zafar
• Robert Schonberger

Critical Care; Postoperative Care; Lung Diseases, Interstitial; Perioperative Care; Diseases; Perioperative Medicine

Antimicrobial Resistance; Bioinformatics; Cardiovascular Diseases; Emerging Infectious Diseases; Infectious Diseases; Pharmaceuticals and Medical Devices

• Pulmonary Hypertension and the Risk of 30-Day Postoperative Pulmonary Complications after Gastrointestinal Surgical or Endoscopic Procedures: A Retrospective Propensity Score-Weighted Cohort AnalysisTatsuoka Y, Carr Z, Jayakumar S, Lin H, He Z, Farroukh A, Heerdt P. Pulmonary Hypertension and the Risk of 30-Day Postoperative Pulmonary Complications after Gastrointestinal Surgical or Endoscopic Procedures: A Retrospective Propensity Score-Weighted Cohort Analysis. Journal Of Clinical Medicine 2024, 13: 1996. PMID: 38610760, PMCID: PMC11012853, DOI: 10.3390/jcm13071996.
• Further innovation is required to enhance risk prediction of postoperative pulmonary complicationsCarr, Z.J. Further innovation is required to enhance risk prediction of postoperative pulmonary complications—comment on Anesthesiol Perioper Sci. 2023;1(4):34. APS 2, 14 (2024). https://doi.org/10.1007/s44254-024-00053-7
• Estimates of 30-day postoperative pulmonary complications after gastrointestinal endoscopic procedures: A retrospective cohort analysis of a health system populationCarr Z, Li J, Agarkov D, Gazura M, Karamchandani K. Estimates of 30-day postoperative pulmonary complications after gastrointestinal endoscopic procedures: A retrospective cohort analysis of a health system population. PLOS ONE 2024, 19: e0299137. PMID: 38394250, PMCID: PMC10889900, DOI: 10.1371/journal.pone.0299137.
• Identifying, Understanding, and Minimizing Unconscious Cognitive Biases in Perioperative Crisis Management: A Narrative Review.Yan L, Karamchandani K, Gaiser R, Carr Z. Identifying, Understanding, and Minimizing Unconscious Cognitive Biases in Perioperative Crisis Management: A Narrative Review. Anesthesia & Analgesia 2023 PMID: 37874227, DOI: 10.1213/ane.0000000000006666.
• Predictors of Failure to Rescue After Postoperative Respiratory Failure: A Retrospective Cohort Analysis of 13,047 Patients Using the ACS-NSQIP DatasetKaramchandani K, Khorsand S, Ebeling C, Yan L, Nakonezny P, Carr Z. Predictors of Failure to Rescue After Postoperative Respiratory Failure: A Retrospective Cohort Analysis of 13,047 Patients Using the ACS-NSQIP Dataset. Journal Of Surgical Research 2023, 293: 482-489. PMID: 37827025, DOI: 10.1016/j.jss.2023.09.030.
• Anesthesia for adult patients with asthmaCarr ZJ. Anesthesia for adult patients with asthma. UpToDate Aug 2023
• Emergency use of sugammadex after failure of standard reversal drugs and postoperative pulmonary complications: A retrospective cohort studyBruceta M, Singh P, Bonavia A, Carr Z, Karamchandani K. Emergency use of sugammadex after failure of standard reversal drugs and postoperative pulmonary complications: A retrospective cohort study. Journal Of Anaesthesiology Clinical Pharmacology 2023, 39: 232-238. PMID: 37564851, PMCID: PMC10410049, DOI: 10.4103/joacp.joacp_289_21.
• Perioperative Pulmonary Complications in the Elderly The Forgotten SystemCarr Z, Siller S, McDowell B. Perioperative Pulmonary Complications in the Elderly The Forgotten System. Anesthesiology Clinics 2023 DOI: 10.1016/j.anclin.2023.02.005.
• Recommendations for Intraoperative Adverse Events Data Collection in Clinical Studies and Study Protocols. An ICARUS Global Surgical Collaboration Study.Cacciamani GE, Eppler M, Sayegh AS, Sholklapper T, Mohideen M, Miranda G, Goldenberg M, Sotelo RJ, Desai MM, Gill IS. Recommendations for Intraoperative Adverse Events Data Collection in Clinical Studies and Study Protocols. An ICARUS Global Surgical Collaboration Study. Int J Surg Protoc 2023, 27: 23-83. PMID: 36818424, DOI: 10.29337/ijsp.183.
• Information Technology-Enhanced Telehealth Consultations Reduce Preoperative Evaluation Center Visits in a Bariatric Surgery PopulationZafar J, Chan K, Ryder L, Duffy A, Dai F, Carr Z, Charchaflieh J. Information Technology-Enhanced Telehealth Consultations Reduce Preoperative Evaluation Center Visits in a Bariatric Surgery Population. Healthcare 2023, 11: 309. PMID: 36766884, PMCID: PMC9914614, DOI: 10.3390/healthcare11030309.
• Perioperative Complications in Patients with Systemic Sclerosis: A Comparative Cohort AnalysisCarr Z, Yan L, Yanez N, Schonberger R, Bohorquez M, He Z, Li F, Hines R, Treggiari M. Perioperative Complications in Patients with Systemic Sclerosis: A Comparative Cohort Analysis. Medical Research Archives 2023, 11: 10.18103/mra.v11i10.4606. PMID: 38037571, PMCID: PMC10688569, DOI: 10.18103/mra.v11i10.4606.
• Perioperative Pulmonary Complications in Geriatric PopulationsCarr ZJ. Perioperative Pulmonary Complications in Geriatric Populations: A costly problem for healthcare systems. Asian Hospital & Healthcare Management. Issue 62, 2023 pp. 26-27
• Cannabis Use Disorder in Critical Illness.Substance Use Disorders in Adult Critically Ill Patients. Chapter: Cannabis Use Disorder in Critical Illness. Springer Nature (in press, 2024)
• A 10-mg dose of amiloride increases time to failure during blood-flow-restricted plantar flexion in healthy adults without influencing blood pressureStavres J, Luck J, Hamaoka T, Blaha C, Cauffman A, Dalton P, Herr MD, Ruiz-Velasco V, Carr Z, Janicki P, Cui J. A 10-mg dose of amiloride increases time to failure during blood-flow-restricted plantar flexion in healthy adults without influencing blood pressure. AJP Regulatory Integrative And Comparative Physiology 2022, 323: r875-r888. PMID: 36222880, PMCID: PMC9678418, DOI: 10.1152/ajpregu.00190.2022.
• Perioperative Management of Patients with Idiopathic Pulmonary Fibrosis Undergoing Noncardiac Surgery: A Narrative ReviewCarr ZJ, Yan L, Chavez-Duarte J, Zafar J, Oprea A. Perioperative Management of Patients with Idiopathic Pulmonary Fibrosis Undergoing Noncardiac Surgery: A Narrative Review. International Journal Of General Medicine 2022, 15: 2087-2100. PMID: 35237071, PMCID: PMC8882471, DOI: 10.2147/ijgm.s266217.
• Pheochromocytoma and MEN Syndromes▪ Carr Z, Farela A, Oprea AD. Pheochromocytoma and MEN syndromes. In Perioperative Medicine: A Problem Based Learning Approach, ed. D. Richman, D. Pulley, A.D. Oprea. Oxford University Press
• Minimally Invasive Esophagectomy▪ Carr Z. Minimally Invasive Esophagectomy. In Video Atlas of Upper and Lower Airway Management, 2nd edition, ed. Rosenblatt W, Popescu W, Ginsberg N. Lippincot, Williams & Wilkins (LWW)
• Persistent Postoperative Vasoplegia After Ureteronephrectomy Due To Suspected Intravesical Gemcitabine ToxicityYan L, Bohorquez MA, Carr ZJ. Persistent Postoperative Vasoplegia After Ureteronephrectomy Due To Suspected Intravesical Gemcitabine Toxicity. A&A Practice 2021, 15: e01537. PMID: 34695040, DOI: 10.1213/xaa.0000000000001537.
• Endocrine emergencies in anesthesiaFernandez-Robles C, Carr ZJ, Oprea AD. Endocrine emergencies in anesthesia. Current Opinion In Anaesthesiology 2021, 34: 326-334. PMID: 33935181, DOI: 10.1097/aco.0000000000000986.
• Comment on: Effect of vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic shock: the VITAMINS randomized clinical trial.Charchaflieh J and Carr Z: Faculty Opinions Recommendation of [Fujii T et al., JAMA 2020 323(5):423-431]. In Faculty Opinions, 15 Apr 2021
• Comment on: Postoperative delirium mediates 180-day mortality in orthopaedic trauma patients.Charchaflieh J and Carr Z: Faculty Opinions Recommendation of [Pedemonte JC et al., Br J Anaesth 2021 127(1):102-109]. In Faculty Opinions, 23 Jul 2021;
• Postoperative Pulmonary Complications: Is it Time for Intensivists to Take the Reins?Society of Critical Care Anesthesiologists Interchange March 2021 (Volume 32, Issue 1)
• Comment on: Is Cardiopulmonary Resuscitation Futile in Coronavirus Disease 2019 Patients Experiencing In-Hospital Cardiac Arrest?Charchaflieh J and Carr Z: Faculty Opinions Recommendation of [Shah P et al., Crit Care Med 2021 49(2):201-208]. In Faculty Opinions, 08 Feb 2021
• Perioperative risk factors in patients with idiopathic pulmonary fibrosis: a historical cohort studyMcDowell BJ, Karamchandani K, Lehman EB, Conboy MJ, Carr ZJ. Perioperative risk factors in patients with idiopathic pulmonary fibrosis: a historical cohort study. Journal Canadien D'anesthésie 2020, 68: 81-91. PMID: 33029686, DOI: 10.1007/s12630-020-01828-9.
• An Update on Systemic Sclerosis and its Perioperative ManagementCarr ZJ, Klick J, McDowell BJ, Charchaflieh JG, Karamchandani K. An Update on Systemic Sclerosis and its Perioperative Management. Current Anesthesiology Reports 2020, 10: 512-521. PMID: 32904358, PMCID: PMC7455511, DOI: 10.1007/s40140-020-00411-8.
• Candida auris: A growing menace in the intensive care unitSociety of Critical Care Anesthesiologists Interchange (2020) (Volume 31, Issue 1)
• Pseudomonas aeruginosa in 500 words (and 5 minutes): A lesson in dynamic evolutionary pressureCarr ZJ. Society of Critical Care Anesthesiologists Interchange (2020) (Volume 31, Issue 3)
• CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial FibrillationKaramchandani K, Schoaps RS, Abendroth T, Carr ZJ, King TS, Bonavia A. CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial Fibrillation. Journal Of Cardiothoracic And Vascular Anesthesia 2019, 34: 1165-1171. PMID: 31899140, DOI: 10.1053/j.jvca.2019.11.044.
• Post‐operative intensive care unit admission after elective non‐cardiac surgery: A single‐center analysis of the NSQIP databaseBruceta M, De Souza L, Carr ZJ, Bonavia A, Kunselman AR, Karamchandani K. Post‐operative intensive care unit admission after elective non‐cardiac surgery: A single‐center analysis of the NSQIP database. Acta Anaesthesiologica Scandinavica 2019, 64: 319-328. PMID: 31710692, DOI: 10.1111/aas.13504.
• In a Model of Neuroinflammation Designed to Mimic Delirium, Quetiapine Reduces Cortisol Secretion and Preserves Reversal Learning in the Attentional Set Shifting TaskCarr ZJ, Miller L, Ruiz-Velasco V, Kunselman AR, Karamchandani K. In a Model of Neuroinflammation Designed to Mimic Delirium, Quetiapine Reduces Cortisol Secretion and Preserves Reversal Learning in the Attentional Set Shifting Task. Journal Of Neuroimmune Pharmacology 2019, 14: 383-390. PMID: 31119596, DOI: 10.1007/s11481-019-09857-y.
• Cardiovascular Collapse in a Patient With Parotid Abscess: Dangerous Cross Talk Between the Brain and Heart: A Case Report.Owusu K, Stredny ES, Williamson G, Carr ZJ, Karamchandani K. Cardiovascular Collapse in a Patient With Parotid Abscess: Dangerous Cross Talk Between the Brain and Heart: A Case Report. A&A Practice 2019, 13: 281-283. PMID: 31385818, DOI: 10.1213/xaa.0000000000001056.
• Stroke prophylaxis in critically-ill patients with new-onset atrial fibrillationSchoaps RS, Quintili A, Bonavia A, Carr ZJ, Lehman EB, Abendroth T, Karamchandani K. Stroke prophylaxis in critically-ill patients with new-onset atrial fibrillation. Journal Of Thrombosis And Thrombolysis 2019, 48: 394-399. PMID: 30963394, DOI: 10.1007/s11239-019-01854-5.
• Pain management in trauma patients affected by the opioid epidemic: A narrative review.Karamchandani K, Klick JC, Linskey Dougherty M, Bonavia A, Allen SR, Carr ZJ. Pain management in trauma patients affected by the opioid epidemic: A narrative review. Journal Of Trauma And Acute Care Surgery 2019, 87: 430-439. PMID: 30939572, DOI: 10.1097/ta.0000000000002292.
• 211: CHA2DS2 VASC SCORE AND IN-HOSPITAL MORTALITY IN PATIENTS WITH NEW-ONSET ATRIAL FIBRILLATIONKaramchandani K, Schoaps R, Carr Z, Bonavia A, Abendroth T. 211: CHA2DS2 VASC SCORE AND IN-HOSPITAL MORTALITY IN PATIENTS WITH NEW-ONSET ATRIAL FIBRILLATION. Critical Care Medicine 2019, 47: 87-87. DOI: 10.1097/01.ccm.0000550966.70503.4b.
• Continuation of atypical antipsychotic medications in critically ill patients discharged from the hospital: a single-center retrospective analysisKaramchandani K, Schoaps RS, Bonavia A, Prasad A, Quintili A, Lehman EB, Carr ZJ. Continuation of atypical antipsychotic medications in critically ill patients discharged from the hospital: a single-center retrospective analysis. Therapeutic Advances In Drug Safety 2018, 10: 2042098618809933. PMID: 31019677, PMCID: PMC6463330, DOI: 10.1177/2042098618809933.
• A double blind randomized placebo controlled pilot study of single-dose preoperative modafinil for functional recovery after general anesthesia in patients with obstructive sleep apneaCarr ZJ, Vells B, Wood BR, Lowery JD, Rogers AM, Kunselman AA, Karamchandani K, Vaida SJ. A double blind randomized placebo controlled pilot study of single-dose preoperative modafinil for functional recovery after general anesthesia in patients with obstructive sleep apnea. Medicine 2018, 97: e12585. PMID: 30278569, PMCID: PMC6181597, DOI: 10.1097/md.0000000000012585.
• Gender differences in the use of atypical antipsychotic medications for ICU deliriumKaramchandani K, Schoaps RS, Printz J, Kowaleski JM, Carr ZJ. Gender differences in the use of atypical antipsychotic medications for ICU delirium. Critical Care 2018, 22: 220. PMID: 30236134, PMCID: PMC6148964, DOI: 10.1186/s13054-018-2143-5.
• Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A ReviewKaramchandani K, Carr Z, Bonavia A, Tung A. Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review. Annals Of The American Thoracic Society 2018, 15: 1016-1023. DOI: 10.1513/annalsats.201801-028cme.
• Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent LiteratureCarr ZJ, Cios TJ, Potter KF, Swick JT. Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent Literature. Current Neurology And Neuroscience Reports 2018, 18: 64. PMID: 30083844, DOI: 10.1007/s11910-018-0873-z.
• Novel Association of Juvenile Polyposis Syndrome With Atrial Septal Aneurysm and Patent Foramen OvaleBruceta M, De Souza L, Carr Z, Bonavia A, Karamchandani K. Novel Association of Juvenile Polyposis Syndrome With Atrial Septal Aneurysm and Patent Foramen Ovale. A&A Practice 2018, 10: 331-334. PMID: 29634562, DOI: 10.1213/xaa.0000000000000714.
• Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A ReviewKaramchandani K, Carr ZJ, Bonavia A, Tung A. Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review. Annals Of The American Thoracic Society 2018, 15: 1016-1023. PMID: 29812953, DOI: 10.1513/annalsats.201801-028fr.
• Organ Dysfunction After Surgery in Patients Treated With Individualized or Standard Blood Pressure ManagementKaramchandani K, Carr ZJ, Bonavia A. Organ Dysfunction After Surgery in Patients Treated With Individualized or Standard Blood Pressure Management. JAMA 2018, 319: 719-719. PMID: 29466585, DOI: 10.1001/jama.2017.20935.
• Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsisCarr ZJ, Van De Louw A, Fehr G, Li JD, Kunselman A, Ruiz-Velasco V. Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis. BMC Research Notes 2018, 11: 41. PMID: 29338778, PMCID: PMC5771199, DOI: 10.1186/s13104-018-3165-4.
• 1173Karamchandani K, Behnam A, Carr Z, Bonavia A. 1173. Critical Care Medicine 2018, 46: 570. DOI: 10.1097/01.ccm.0000529178.51840.d4.
• Does Every Code Need a “Reader?” Improvement of Rare Event Management With a Cognitive Aid “Reader” During a Simulated EmergencyBurden AR, Carr ZJ, Staman GW, Littman JJ, Torjman MC. Does Every Code Need a “Reader?” Improvement of Rare Event Management With a Cognitive Aid “Reader” During a Simulated Emergency. Simulation In Healthcare The Journal Of The Society For Simulation In Healthcare 2012, 7: 1-9. PMID: 22113440, DOI: 10.1097/sih.0b013e31822c0f20.
• Spatial Memory Using Active Allothetic Place Avoidance in Adult Rats After Isoflurane AnesthesiaCarr ZJ, Torjman MC, Manu K, Dy G, Goldberg ME. Spatial Memory Using Active Allothetic Place Avoidance in Adult Rats After Isoflurane Anesthesia. Journal Of Neurosurgical Anesthesiology 2011, 23: 138-145. PMID: 21270646, DOI: 10.1097/ana.0b013e3182049f19.
• Ball valve effect precipitating an anesthesia circuit obstruction by an intravenous set cap within the elbow connectorCarr ZJ, Deal ER, Goldberg ME. Ball valve effect precipitating an anesthesia circuit obstruction by an intravenous set cap within the elbow connector. Journal Of Clinical Anesthesia 2010, 22: 486-487. PMID: 20868975, DOI: 10.1016/j.jclinane.2009.12.009.