Kalpana Raja
PhD, MRSB, CSci
Instructor of Biomedical Informatics and Data Science
Research & Publications
Biography
News
Selected Publications
- Integrated Approaches to Identify miRNA Biomarkers Associated with Cognitive Dysfunction in Multiple Sclerosis Using Text Mining, Gene Expression, Pathways, and GWAS.Prabahar A, Raja K. Integrated Approaches to Identify miRNA Biomarkers Associated with Cognitive Dysfunction in Multiple Sclerosis Using Text Mining, Gene Expression, Pathways, and GWAS. Diagnostics (Basel) 2022, 12 PMID: 36010264, DOI: 10.3390/diagnostics12081914.
- Extracting Significant Comorbid Diseases from MeSH Index of PubMed.Anand D, Manoharan S, Iyyappan OR, Anand S, Raja K. Extracting Significant Comorbid Diseases from MeSH Index of PubMed. Methods Mol Biol 2022, 2496: 283-299. PMID: 35713870, DOI: 10.1007/978-1-0716-2305-3_15.
- Advancement in predicting interactions between drugs used to treat psoriasis and its comorbidities by integrating molecular and clinical resources.Patrick MT, Bardhi R, Raja K, He K, Tsoi LC. Advancement in predicting interactions between drugs used to treat psoriasis and its comorbidities by integrating molecular and clinical resources. J Am Med Inform Assoc 2021, 28: 1159-1167. PMID: 33544847, DOI: 10.1093/jamia/ocaa335.
- A summary on up-to-date research on fungal siderophores on disease, treatment and pathogenicity based on text mining, bioinformatics and experts’ opinionPrabahar, A., Shanmugam, L., Jose, M.A., Radhakrishnan, K.M., & Raja, K. A summary on up-to-date research on fungal siderophores on disease, treatment and pathogenicity based on text mining, bioinformatics and experts’ opinion. Springer Nature: Fungal siderophores – From Mineral-Microbe Interactions to Anti-pathogenecity. 2021, 187-210.
- Caenorhabditis elegans as a possible model to screen anti-Alzheimer's therapeutics.Paul D, Chipurupalli S, Justin A, Raja K, Mohankumar SK. Caenorhabditis elegans as a possible model to screen anti-Alzheimer's therapeutics. J Pharmacol Toxicol Methods 2020, 106: 106932. PMID: 33091537, DOI: 10.1016/j.vascn.2020.106932.
- Automated Extraction and Visualization of Protein-Protein Interaction Networks and Beyond: A Text-Mining Protocol.Raja K, Natarajan J, Kuusisto F, Steill J, Ross I, Thomson J, Stewart R. Automated Extraction and Visualization of Protein-Protein Interaction Networks and Beyond: A Text-Mining Protocol. Methods Mol Biol 2020, 2074: 13-34. PMID: 31583627, DOI: 10.1007/978-1-4939-9873-9_2.
- Hypersensitive IFN Responses in Lupus Keratinocytes Reveal Key Mechanistic Determinants in Cutaneous Lupus.Tsoi LC, Hile GA, Berthier CC, Sarkar MK, Reed TJ, Liu J, Uppala R, Patrick M, Raja K, Xing X, Xing E, He K, Gudjonsson JE, Kahlenberg JM. Hypersensitive IFN Responses in Lupus Keratinocytes Reveal Key Mechanistic Determinants in Cutaneous Lupus. J Immunol 2019, 202: 2121-2130. PMID: 30745462, DOI: 10.4049/jimmunol.1800650.
- Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach.Patrick MT, Raja K, Miller K, Sotzen J, Gudjonsson JE, Elder JT, Tsoi LC. Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach. J Invest Dermatol 2019, 139: 683-691. PMID: 30342048, DOI: 10.1016/j.jid.2018.09.018.
- Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients.Patrick MT, Stuart PE, Raja K, Gudjonsson JE, Tejasvi T, Yang J, Chandran V, Das S, Callis-Duffin K, Ellinghaus E, Enerbäck C, Esko T, Franke A, Kang HM, Krueger GG, Lim HW, Rahman P, Rosen CF, Weidinger S, Weichenthal M, Wen X, Voorhees JJ, Abecasis GR, Gladman DD, Nair RP, Elder JT, Tsoi LC. Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients. Nat Commun 2018, 9: 4178. PMID: 30301895, DOI: 10.1038/s41467-018-06672-6.
- Mining protein phosphorylation information from biomedical literature using NLP parsing and Support Vector Machines.Raja K, Natarajan J. Mining protein phosphorylation information from biomedical literature using NLP parsing and Support Vector Machines. Comput Methods Programs Biomed 2018, 160: 57-64. PMID: 29728247, DOI: 10.1016/j.cmpb.2018.03.022.