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    Denise Esserman, PhD

    Professor of Biostatistics
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    Professor of Biostatistics

    Biography

    Denise Esserman joined the Yale School of Public Health faculty in 2014 as an associate professor of biostatistics. She is interested in methods related to clustered randomized trials and the impact of the ICC and other factors on calculating sample size. As a member of the Yale Center for Analytical Sciences, she collaborates with a number of departments at the Yale School of Medicine, including the Clinical and Translational Science Award Program, Patient-Centered Outcomes Research Institute, and the Cancer Center. She has reviewed articles for the American Journal of Epidemiology, Arteriosclerosis, Thrombosis and Vascular Biology; Statistics in Biopharmaceutical Research; Clinical Trials; and Obesity. Esserman earned her doctorate at Columbia University and has since taught at the University of North Carolina, Chapel Hill.

    Last Updated on April 07, 2025.

    Appointments

    Other Departments & Organizations

    Education & Training

    PhD
    Columbia University (2006)
    MS
    University of Georgia (2001)

    Research

    Overview

    Medical Research Interests

    Biostatistics; Longitudinal Studies; Public Health; Randomized Controlled Trial; Sampling Studies

    Research Projects

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Denise Esserman's published research.

    Publications

    2026

    • The Veteran Affairs’ Whole Health Approach for Chronic Pain Management
      Seal K, Morasco B, Martin A, Reddy K, Van Iseghem T, Bolton R, Bokhour B, Murphy J, Denneson L, Esserman D, Buta E, Purcell N, Bertenthal D, Painter J, Abadjian L, Moore L, Chan A, McCamish N, Maguen S, Neylan T, Gibson C, Becker W, Adams M, Allen R, Ankawi B, Bailey D, Bay W, Beglane M, Berry-Hyatt T, Bess C, Blankenship A, Blankenship E, Borsari B, Burgo L, Burton C, Cagnina M, Chadwell R, Chun V, Cline B, Collins D, Cristoferi K, Dante G, Dayton-Keyhoe A, DeBar L, DeRonne B, Dougherty J, Edmond S, Eichelsdoerfer E, Etzel B, Fabian E, Feinberg T, Frank J, Gagnon T, Garvey C, George K, Greaves D, Greene C, Gregg E, Guo L, Hagedorn H, Hardaway A, Haywood C, Hildebrand C, Hill L, Hillgren K, Hixson J, Hokazano A, Horn J, Hubbard A, Hudson T, Huffer M, Ibarra J, Jacobson C, Jeffries J, Jenkins D, Jones M, Joseph J, Khanna M, Klayman J, Krebs E, Krishnaswamy A, Kuhn A, Lederer V, Lee T, Lisi A, Lucas L, Mack J, Majoris N, Makonnen R, Mathias M, Mazzone K, Miller E, Morgan C, Munusami M, Nguyen Y, Nieves Y, Noack A, Noonan K, Palyo S, Parker J, Parrilla D, Pierce W, Pitts S, Prasad L, Pyne J, Raciborski R, Ramirez T, Rankin S, Richards L, Roca H, Rodenkirch I, Rodriguez Y, Rudroff K, Saeed A, Seidel I, Sewell K, Shah R, Sivilich H, Suitter J, Torres R, Valenti A, Vannier R, Vassilieva S, Wells M, Wentross J, Wesolowicz D, Woodruff N, Yap E, Yeung C, Ying A, Zuniga S. The Veteran Affairs’ Whole Health Approach for Chronic Pain Management. JAMA: The Journal Of The American Medical Association 2026, 335: 1774-1786. PMID: 42054020, PMCID: PMC13130068, DOI: 10.1001/jama.2026.5006.
      Peer-Reviewed Original Research
    • A Cluster Randomized Trial of a Vaccination Communication Educational Intervention: Impact on COVID-19 Vaccine Uptake in Veterans
      Seal K, Kaplan A, Manuel J, Bertenthal D, Purcell N, DeRonne B, Oliver K, Esserman D, McCamish N, Mesidor M, Griffin B, Borsari B, Woodruff N, Usman H, Pyne J. A Cluster Randomized Trial of a Vaccination Communication Educational Intervention: Impact on COVID-19 Vaccine Uptake in Veterans. Journal Of General Internal Medicine 2026, 41: 2217-2226. PMID: 41680545, PMCID: PMC13241570, DOI: 10.1007/s11606-026-10209-9.
      Peer-Reviewed Original Research
    • A joint distribution for indexes of extremes with applications to climate change
      Yu C, Kane M, Blaha O, Wei W, Esserman D, Zelterman D. A joint distribution for indexes of extremes with applications to climate change. Statistics And Its Interface 2026, 19: 197-209. DOI: 10.4310/sii.260108021930.
      Peer-Reviewed Original Research
      This study investigates trends in extreme temperature records in Annapolis, Maryland, showing for the 365 calendar days, record highs occur more recently than record lows, indicating warming trends.
      Full Summary

    2025

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