Anna Lynn, MD, PhD
Hospital ResidentAbout
Research
Publications
2026
Prenatal Intraportal Delivery of Polymeric Nanoparticles to Fetal Rhesus Monkeys (Macaca mulatta)
Piotrowski-Daspit A, Lynn A, Eaton D, Bracaglia L, Markey A, Mortlock R, Stitelman D, Martinez M, Lee C, Kliman H, Glazer P, Tarantal A, Saltzman W. Prenatal Intraportal Delivery of Polymeric Nanoparticles to Fetal Rhesus Monkeys (Macaca mulatta). Human Gene Therapy 2026, 37: 189-198. PMID: 41645533, PMCID: PMC12978997, DOI: 10.1177/10430342251414881.Peer-Reviewed Original Research
2025
Systemic in utero gene editing as a treatment for cystic fibrosis
Ricciardi A, Barone C, Putman R, Quijano E, Gupta A, Nguyen R, Mandl H, Piotrowski-Daspit A, Lopez-Giraldez F, Luks V, Freedman-Weiss M, Farrelly J, Ahle S, Lynn A, Glazer P, Saltzman W, Stitelman D, Egan M. Systemic in utero gene editing as a treatment for cystic fibrosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2418731122. PMID: 40493185, PMCID: PMC12184489, DOI: 10.1073/pnas.2418731122.Peer-Reviewed Original ResearchInvestigation of the protein corona and biodistribution profile of polymeric nanoparticles for intra-amniotic delivery
Lynn A, Shin K, Eaton D, Rose M, Zhang X, Ene M, Grundler J, Deschenes E, Rivero R, Bracaglia L, Glazer P, Stitelman D, Saltzman W. Investigation of the protein corona and biodistribution profile of polymeric nanoparticles for intra-amniotic delivery. Biomaterials 2025, 320: 123238. PMID: 40064138, PMCID: PMC11972154, DOI: 10.1016/j.biomaterials.2025.123238.Peer-Reviewed Original ResearchPTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors
DeSpenza T, Kiziltug E, Allington G, Barson D, McGee S, O’Connor D, Robert S, Mekbib K, Nanda P, Greenberg A, Singh A, Duy P, Mandino F, Zhao S, Lynn A, Reeves B, Marlier A, Getz S, Nelson-Williams C, Shimelis H, Walsh L, Zhang J, Wang W, Prina M, OuYang A, Abdulkareem A, Smith H, Shohfi J, Mehta N, Dennis E, Reduron L, Hong J, Butler W, Carter B, Deniz E, Lake E, Constable R, Sahin M, Srivastava S, Winden K, Hoffman E, Carlson M, Gunel M, Lifton R, Alper S, Jin S, Crair M, Moreno-De-Luca A, Luikart B, Kahle K. PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors. Nature Neuroscience 2025, 28: 536-557. PMID: 39994410, PMCID: PMC12038823, DOI: 10.1038/s41593-024-01865-3.Peer-Reviewed Original Research
2024
Opportunities for Incorporation of Primary Palliative Care in Acute Care Surgery: A Narrative Review
Lynn A, Miller S, Brackett A, Kodadek L. Opportunities for Incorporation of Primary Palliative Care in Acute Care Surgery: A Narrative Review. American Journal Of Hospice And Palliative Medicine® 2024, 43: 113-122. PMID: 39680802, DOI: 10.1177/10499091241309087.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsBiodistribution of Polymeric Nanoparticles following in utero Delivery to a Nonhuman Primate
Eaton D, Lynn A, Surprenant J, Deschenes E, Guerra M, Rivero R, Yung N, O'Connor M, Glazer P, Bahtiyar M, Saltzman W, Stitelman D. Biodistribution of Polymeric Nanoparticles following in utero Delivery to a Nonhuman Primate. Biomedicine Hub 2024, 10: 543138. PMID: 39845408, PMCID: PMC11753793, DOI: 10.1159/000543138.Peer-Reviewed Original ResearchThe Association of Polycystic Ovarian Syndrome and Adnexal Pathologies in Adolescents
Lynn A, Lepore C, Solomon N, Zamani M, Sailer A, Kuehne A, Rowe E, Vash-Margita A. The Association of Polycystic Ovarian Syndrome and Adnexal Pathologies in Adolescents. Journal Of Obstetrics And Gynaecology Canada 2024, 46: 102634. PMID: 39142633, DOI: 10.1016/j.jogc.2024.102634.Peer-Reviewed Original ResearchThe Technical and Ethical framework of Fetal Therapy: Past and Current Advances
Lynn, A.Y., Glazer, P.M., Saltzman, W.M. et al. The Technical and Ethical Framework of Fetal Therapy: Past and Current Advances. Curr Stem Cell Rep 10, 30–36 (2024). https://doi.org/10.1007/s40778-024-00235-wPeer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThe Technical and Ethical Framework of Fetal Therapy: Past and Current Advances
Lynn A, Glazer P, Saltzman W, Stitelman D. The Technical and Ethical Framework of Fetal Therapy: Past and Current Advances. Current Stem Cell Reports 2024, 10: 30-36. PMID: 41048874, PMCID: PMC12490801, DOI: 10.1007/s40778-024-00235-w.Peer-Reviewed Original Research
2022
Evaluation of the Association of Endometrial Thickness, Insulin Resistance, and Menstrual Patterns in Adolescent Females with Polycystic Ovarian Syndrome
Lynn A, Solomon N, Zamani M, Rowe E, Seifer D, Vash-Margita A. Evaluation of the Association of Endometrial Thickness, Insulin Resistance, and Menstrual Patterns in Adolescent Females with Polycystic Ovarian Syndrome. Journal Of Pediatric And Adolescent Gynecology 2022, 36: 134-139. PMID: 36403727, DOI: 10.1016/j.jpag.2022.11.005.Peer-Reviewed Original Research
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