Pre-Doctoral Training Program

Multidisciplinary Pre-Doctoral Training Program in Translational Research


John Forrest, MD
Director of the Office of Student Research

In 2005, Yale established a multidisciplinary, T-supported institutional training program for pre-doctoral medical as well as nursing and biomedical engineering students with the goals of introducing them to clinical and translational research and of encouraging them to pursue research careers. This program takes maximum advantage of the resources at Yale, including: the medical student thesis program (all medical students at Yale are required to do a thesis as a requirement to graduate); the established research training programs at Yale spanning the spectrum of clinical and translational (T1-T4) research; the Masters of Health Science degree program (described below); and faculty with strengths as experienced mentors in clinical and translational research and multi-disciplinary training. Pre-doctoral students are supported by the TL1 grant for one-year research fellowships including: medical students doing a 5th year of research and training, as well as pre-doctoral students from the MD-PhD program and the PhD programs at the School of Nursing and the Department of Biomedical Engineering. The program is supported in many ways, such as waiving tuition for the additional year of training for medical students. The centerpiece of the MPDTP is the MHS degree for students who complete specific course requirements and a clinical/translational research project under the supervision of a faculty mentor and a thesis committee. All students participate in monthly Research-in- Progress meetings (each student presents twice/year), a journal club, and courses, as well as a separate lecture and dinner series on leadership, where selected senior faculty members discuss issues (family, mentors, inclusion and diversity) relevant to students choosing a career in academic medicine and research. Yale students supported by the TL1 training grant have achieved a remarkable record of scientific productivity as evidenced by the number of abstracts, full-length publications, and presentations at regional and national scientific meetings. MPDTP students have authored 442 publications in many outstanding peer-reviewed journals including Nature, Proceedings of the National Academy of Sciences, Circulation, JAMA, Neuroscience, Journal of Neuroscience, Journal of Immunology, Journal of the American College of Cardiology and the American Heart Journal, among others. Click here for more information about student research.

More information about the TL1 Program: