2016
Voltage-Gated Ion Channels as Molecular Targets for Pain
Zamponi G, Han C, Waxman S. Voltage-Gated Ion Channels as Molecular Targets for Pain. 2016, 415-436. DOI: 10.1007/978-1-4899-7654-3_22.Peer-Reviewed Original ResearchVoltage-gated ion channelsDorsal root ganglion neuronsIon channelsMolecular targetsAction potential firing propertiesTreatment of painVoltage-gated sodiumImportant ion channelsNerve injuryGanglion neuronsPain signalingPeripheral afferentsPainFiring propertiesPharmacological modulatorsPotassium channelsTranslational researchDevelopment of modulatorsFunction changesHyperexcitabilityAfferentsInflammationMajor roleMajor themesInjury
1990
Immuno-Localization of Sodium Channels in Axon Membrane and Astrocytes and Schwann Cells in vivo and in vitro
Black J, Friedman B, Cornell-Bell A, Angelides K, Ritchie J, Waxman S. Immuno-Localization of Sodium Channels in Axon Membrane and Astrocytes and Schwann Cells in vivo and in vitro. NATO ASI Series 1990, 81-97. DOI: 10.1007/978-3-642-83968-9_6.Peer-Reviewed Original ResearchSodium channelsGlial cellsSchwann cellsSodium channel immunoreactivityProcesses of astrocytesMammalian CNS tissueBrain sodium channelsVoltage-sensitive sodium channelsNodes of RanvierChannel immunoreactivityRat brain sodium channelsCNS tissueIntense immunostainingAstrocytesImmuno-localizationCellsAxon membraneVivoMajor roleImmunoreactivityImmunostaining