Signaling Via the T Cell Receptor
Singer A, Jordan M, Judd B, Myung P, Newbrough S, Nichols K, Olenchock B, Peterson E, Wu J, Zhong X, Koretzky G. Signaling Via the T Cell Receptor. Science Signaling 2003, 2003 DOI: 10.1126/stke.2003.194.cm7.Peer-Reviewed Original ResearchRas-mitogen-activated protein kinaseSrc homology 2 domainPhospholipase C-γ1 activationT cell signal transductionProtein kinase C θCell signal transductionT cell activationT cell receptor engagementTranscription factor nuclear factorCell receptor engagementRas guanineSLP-76Cytoplasmic domainSignal transductionSrc familyProtein kinaseActivation motifCell activationDownstream targetsMAP pathwayCleavage of phosphatidylinositolNegative regulatorGene expressionProximal regulatorSecond messenger