2021
Disparities in perinatal health: what can we do?
Forson-Dare Z, Harris LM, Gallagher PG. Disparities in perinatal health: what can we do? Journal Of Perinatology 2021, 41: 363-364. PMID: 33510417, DOI: 10.1038/s41372-021-00920-2.Peer-Reviewed Original ResearchCritical disparities in perinatal health—understanding risks and changing the outcomes
Harris LM, Forson-Dare Z, Gallagher PG. Critical disparities in perinatal health—understanding risks and changing the outcomes. Journal Of Perinatology 2021, 41: 181-182. PMID: 33462341, DOI: 10.1038/s41372-020-00913-7.Peer-Reviewed Original Research
2020
Perinatal aspects on the covid-19 pandemic: a practical resource for perinatal–neonatal specialists
Mimouni F, Lakshminrusimha S, Pearlman SA, Raju T, Gallagher PG, Mendlovic J. Perinatal aspects on the covid-19 pandemic: a practical resource for perinatal–neonatal specialists. Journal Of Perinatology 2020, 40: 820-826. PMID: 32277162, PMCID: PMC7147357, DOI: 10.1038/s41372-020-0665-6.Peer-Reviewed Original ResearchConceptsPerinatal aspectsCOVID-19 infectionCOVID-19SARS-CoV-2Maternal infectionThird trimesterEarly pregnancyPregnant womenRisk factorsSevere diseaseHuman milkDisease severityVertical transmissionAvailable evidenceGoogle ScholarCOVID-19 informationWomenPregnancyNeonatesCOVID-19 pandemicWebsites of organizationsInfectionAvailable literatureCurrent knowledgePandemicWhy so little progress in regionalization of perinatal care when transport of high-risk neonates remains a substantial risk?
Bizzarro MJ, Gallagher PG. Why so little progress in regionalization of perinatal care when transport of high-risk neonates remains a substantial risk? Journal Of Perinatology 2020, 40: 357-358. PMID: 31996764, DOI: 10.1038/s41372-020-0600-x.Peer-Reviewed Original Research
2011
Perinatal Onset Mevalonate Kinase Deficiency
Steiner LA, Ehrenkranz RA, Peterec SM, Steiner RD, Reyes-Múgica M, Gallagher PG. Perinatal Onset Mevalonate Kinase Deficiency. Pediatric And Developmental Pathology 2011, 14: 301-306. PMID: 21425920, DOI: 10.2350/11-02-0985-oa.1.Peer-Reviewed Original ResearchConceptsMevalonate kinase deficiencyPeriodic fever syndromeNeonatal periodKinase deficiencyFever syndromeDysmorphic featuresCentral nervous system abnormalitiesIntrauterine viral infectionCholestatic liver diseaseIntrauterine growth restrictionImmediate neonatal periodNervous system abnormalitiesSevere multisystem disorderSepsis syndromeRenal failureCerebral ventriculomegalyLiver diseasePersistent diarrheaClinical findingsPoor prognosisAutopsy findingsGrowth restrictionRare conditionExtramedullary erythropoiesisPerinatal periodPartial Exchange Transfusion for Polycythemia Hyperviscosity Syndrome
Hopewell B, Steiner L, Ehrenkranz R, Bizzarro M, Gallagher P. Partial Exchange Transfusion for Polycythemia Hyperviscosity Syndrome. American Journal Of Perinatology 2011, 28: 557-564. PMID: 21365533, DOI: 10.1055/s-0031-1274504.Peer-Reviewed Original ResearchConceptsPartial exchange transfusionPercent of patientsRisk factorsMaternal diabetesExchange transfusionSignificant complicationsHyperviscosity syndromeNeonatal intensive care unitYale-New Haven HospitalLife-threatening complicationsLong-term followIntensive care unitNeonatal medical recordsPatient demographicsRetrospective reviewCare unitMedical recordsRisk populationsComplicationsPatientsStudy periodSignificant decreaseTransfusionDiabetesSyndromeSingle-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo
Isern J, He Z, Fraser ST, Nowotschin S, Ferrer-Vaquer A, Moore R, Hadjantonakis AK, Schulz V, Tuck D, Gallagher PG, Baron MH. Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo. Blood 2011, 117: 4924-4934. PMID: 21263157, PMCID: PMC3100699, DOI: 10.1182/blood-2010-10-313676.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCell LineageCytokinesDNA PrimersEpsilon-GlobinsErythroid Precursor CellsErythropoiesisFemaleGene Expression ProfilingGene Expression Regulation, DevelopmentalGene Regulatory NetworksGlycolysisGreen Fluorescent ProteinsGrowth SubstancesMaleMiceMice, Inbred ICRMice, TransgenicOxygenPregnancyRecombinant Fusion ProteinsRNA, MessengerSignal TransductionConceptsPrimitive erythroid progenitorsMouse embryosErythroid progenitorsGlobal expression profilesEmbryonic day 7.5Critical regulatory factorKey regulatory pathwaysOnset of circulationFirst transcriptomeRemarkable proliferative capacityTranscript diversityTransgenic reporterTranscriptome analysisFirst cell typeRegulatory pathwaysHematopoietic lineagesExpression profilesRegulatory factorsCell typesDay 7.5EmbryosProgenitorsYolk sacBlood progenitorsGlycolytic profile
2008
Changing Patterns in Neonatal Escherichia coli Sepsis and Ampicillin Resistance in the Era of Intrapartum Antibiotic Prophylaxis
Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. Changing Patterns in Neonatal Escherichia coli Sepsis and Ampicillin Resistance in the Era of Intrapartum Antibiotic Prophylaxis. Pediatrics 2008, 121: 689-696. PMID: 18381532, DOI: 10.1542/peds.2007-2171.Peer-Reviewed Original ResearchMeSH KeywordsAmpicillinAmpicillin ResistanceAntibiotic ProphylaxisBacteremiaEscherichia coliEscherichia coli InfectionsFemaleFollow-Up StudiesHumansIncidenceInfant, NewbornInfectious Disease Transmission, VerticalMaleMultivariate AnalysisOdds RatioPregnancyPregnancy Complications, InfectiousPrenatal CareProbabilityRetrospective StudiesRisk AssessmentSeverity of Illness IndexStatistics, NonparametricSurvival RateConceptsE. coli early-onset sepsisEarly-onset sepsisLate-onset sepsisYale-New Haven HospitalIntrapartum antibiotic prophylaxisAntibiotic prophylaxisColi sepsisLow birth weight infantsAmpicillin resistanceAntibiotic prophylaxis practiceIntrapartum antibiotic exposureBirth weight infantsE. coli sepsisIndependent risk factorEscherichia coli sepsisAmpicillin exposureAmpicillin-resistant E. coliProphylaxis practicesSepsis rateWeight infantsNeonatal sepsisPreterm infantsTerm infantsRetrospective reviewRisk factors
2001
Three‐dimensional sonographic imaging of a highly developed fetus in fetu with spontaneous movement of the extremities.
Jones DC, Reyes-Múgica M, Gallagher PG, Fricks P, Touloukian RJ, Copel JA. Three‐dimensional sonographic imaging of a highly developed fetus in fetu with spontaneous movement of the extremities. Journal Of Ultrasound In Medicine 2001, 20: 1357-1363. PMID: 11762548, DOI: 10.7863/jum.2001.20.12.1357.Peer-Reviewed Original Research
1999
Molecular diagnosis of hemoglobinopathies and other red blood cell disorders.
Arcasoy MO, Gallagher PG. Molecular diagnosis of hemoglobinopathies and other red blood cell disorders. Seminars In Hematology 1999, 36: 328-39. PMID: 10530715.Peer-Reviewed Original ResearchMeSH KeywordsCytogenetic AnalysisErythrocytesFemaleHematologic DiseasesHemoglobinopathiesHumansMalePregnancyConceptsAppropriate prenatal counselingAppropriate patient educationRed blood cell disordersMolecular diagnosisBlood cell disordersClinical outcomesPatient educationRisk individualsCell disordersClinical practicePrenatal counselingRapid genetic diagnosisRapid diagnosisDiagnosisEarly detectionErythrocyte disordersRisk couplesDisordersPrenatal diagnosisGenetic diagnosisHemoglobinopathiesMolecular biologyCystic hygroma in the fetus and newborn
Gallagher P, Mahoney M, Gosche J. Cystic hygroma in the fetus and newborn. Seminars In Perinatology 1999, 23: 341-356. PMID: 10475547, DOI: 10.1016/s0146-0005(99)80042-1.Peer-Reviewed Original ResearchConceptsCystic hygromaLymphatic system abnormalitiesNonsurgical therapyDisease courseOverall prognosisBetter prognosisClinical coursePathologic correlatesPosterior neckSystem abnormalitiesLymphoid systemHygromaKaryotypic abnormalitiesMalformation syndromeAbnormalitiesTeratogenic agentsPrognosisDevelopmental abnormalitiesFetusesNeonatesSyndromeInfantsTherapyNeckCourse