2022
Metagenomic sequencing of the bronchoalveolar lavage extracellular virome and cellular transcriptome of sarcoidosis patients does not detect rubella virus
Keeler E, Vukmirovic M, Yan X, Gulino K, Ghedin E, Kaminski N, Sullivan K, Bushman F, Collman R, Rosenbach M. Metagenomic sequencing of the bronchoalveolar lavage extracellular virome and cellular transcriptome of sarcoidosis patients does not detect rubella virus. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases 2022, 39: e2022040. PMID: 36533601, PMCID: PMC9798337, DOI: 10.36141/svdld.v39i4.13407.Peer-Reviewed Original ResearchSarcoidosis patientsRubella virusBronchoalveolar lavageMultisystem granulomatous inflammatory diseaseImmune-competent patientsRubella virus infectionGranulomatous inflammatory diseaseCutaneous sarcoidosisAntigenic triggerBAL cellsUnclear etiologyRubella virus genomeInflammatory diseasesCutaneous granulomasGranulomatous lesionsVirus infectionVirus gene expressionLung samplesAcellular fluidCompetent patientsPatientsSarcoidosisOverlapping featuresMetagenomic sequencingVirus
2013
Oral Antimycobacterial Therapy in Chronic Cutaneous Sarcoidosis: A Randomized, Single-Masked, Placebo-Controlled Study
Drake WP, Oswald-Richter K, Richmond BW, Isom J, Burke VE, Algood H, Braun N, Taylor T, Pandit KV, Aboud C, Yu C, Kaminski N, Boyd AS, King LE. Oral Antimycobacterial Therapy in Chronic Cutaneous Sarcoidosis: A Randomized, Single-Masked, Placebo-Controlled Study. JAMA Dermatology 2013, 149: 1040-1049. PMID: 23863960, PMCID: PMC3927541, DOI: 10.1001/jamadermatol.2013.4646.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdultAgedAnti-Bacterial AgentsAzithromycinCD4-Positive T-LymphocytesChronic DiseaseDrug Therapy, CombinationEthambutolFemaleFollow-Up StudiesHumansLevofloxacinMaleMiddle AgedOfloxacinRifampinSarcoidosisSeverity of Illness IndexSingle-Blind MethodSkin DiseasesTranscriptomeTreatment OutcomeYoung AdultConceptsChronic cutaneous sarcoidosisCutaneous sarcoidosis lesionsAntimycobacterial therapyLesion diameterCutaneous sarcoidosisSarcoidosis lesionsDisease severityPlacebo-controlled studyPlacebo-treated groupCompletion of therapyT cell functionChronic granulomatous diseaseT cell receptor stimulationSignificant reductionConcomitant levofloxacinPlacebo regimenRifampin regimenSingle-MaskedPlacebo groupTreat analysisDermatology centersTherapeutic optionsGranulomatous diseaseT cellsLesion severity