2011
Remyelination after olfactory ensheathing cell transplantation into diverse demyelinating environments
Sasaki M, Lankford KL, Radtke C, Honmou O, Kocsis JD. Remyelination after olfactory ensheathing cell transplantation into diverse demyelinating environments. Experimental Neurology 2011, 229: 88-98. PMID: 21281634, DOI: 10.1016/j.expneurol.2011.01.010.Peer-Reviewed Original ResearchConceptsCell transplantationDemyelinated spinal cord axonsMacrophage/microglia activationMost rodent modelsEndogenous myelin repairSpinal cord axonsNervous system repairMyelin-forming cellsMicroglia activationDemyelination modelDemyelinated lesionsLesion environmentActive demyelinationMyelin repairMyelin debrisRemyelination potentialInflammatory signalingRodent modelsLesion inductionRemyelinationExperimental remyelinationTransplantationTransplant studiesOECsHuman progenitors
2008
18 MULTIPLE SCLEROSIS: REMYELINATION
KOCSIS J, SASAKI M, LANKFORD K, RADTKE C. 18 MULTIPLE SCLEROSIS: REMYELINATION. 2008, 413-435. DOI: 10.1016/b978-012373994-0.50020-8.Peer-Reviewed Original ResearchMyelin-forming cellsMultiple sclerosisConduction abnormalitiesPotential neuroprotective effectsProminent pathological featurePeripheral nervous systemEndogenous progenitor cellsPotassium channel distributionRemyelinated axonsIon channel organizationDemyelinated lesionsNeuroprotective effectsAxonal transectionPathological featuresFunctional deficitsMyelin repairAxonal repairMyelin resultsNervous systemImpulse conductionProgenitor cellsRemyelinationSclerosisTransectionAbnormalities