2006
Myelination and nodal formation of regenerated peripheral nerve fibers following transplantation of acutely prepared olfactory ensheathing cells
Dombrowski MA, Sasaki M, Lankford KL, Kocsis JD, Radtke C. Myelination and nodal formation of regenerated peripheral nerve fibers following transplantation of acutely prepared olfactory ensheathing cells. Brain Research 2006, 1125: 1-8. PMID: 17112480, PMCID: PMC2673087, DOI: 10.1016/j.brainres.2006.09.089.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedCell Adhesion Molecules, NeuronalCell TransplantationGreen Fluorescent ProteinsImmunohistochemistryMicroscopy, ImmunoelectronMyelin SheathNAV1.6 Voltage-Gated Sodium ChannelNerve RegenerationNeurofilament ProteinsNeurogliaOlfactory BulbRanvier's NodesRatsRats, Sprague-DawleySciatic NeuropathySodium ChannelsTime FactorsConceptsPeripheral nerve fibersPeripheral nervesNodes of RanvierFunctional outcomeAxonal regenerationNerve fibersRegenerated peripheral nerve fibersSciatic nerve crush lesionNerve crush lesionPeripheral-type myelinSpinal cord resultsTransplantation of olfactoryPeripheral axonal regenerationParanodal CasprCrush lesionCord resultsFunctional improvementOlfactory bulbTransection siteTransgenic ratsLesion zoneNerveNodal formationTransplantation siteOECs
2001
Hepatocyte growth factor is a mitogen for olfactory ensheathing cells
Yan H, Nie X, Kocsis J. Hepatocyte growth factor is a mitogen for olfactory ensheathing cells. Journal Of Neuroscience Research 2001, 66: 698-704. PMID: 11746390, PMCID: PMC2605377, DOI: 10.1002/jnr.10009.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesBrain Tissue TransplantationCell DivisionCell SizeCell SurvivalCells, CulturedColforsinCulture Media, Serum-FreeCyclic AMPDose-Response Relationship, DrugDrug InteractionsFemaleGlial Fibrillary Acidic ProteinHepatocyte Growth FactorImmunohistochemistryMitogensNeurogliaOlfactory BulbProto-Oncogene Proteins c-metRatsRats, WistarReceptor, Nerve Growth FactorS100 ProteinsTrauma, Nervous SystemConceptsHepatocyte growth factorActivity of HGFAdult rat olfactory bulbHGF/c-Met systemGrowth factorOEC proliferationMitogenic activityOlfactory Ensheathing CellsRat olfactory bulbAbility of HGFC-Met receptorAddition of forskolinCultured OECsOlfactory bulbVariety of cellsDNA synthesisC-MetSerum-free mediumPotential mitogenic activityPotent mitogenMulti-functional effectsImmunocytochemical analysisCell proliferationOlfactory systemOECs
2000
[Comparison of myelin-forming cells as candidates for therapeutic transplantation in demyelinated CNS axons].
Imaizumi T, Lankford K, Kocsis J, Sasaki M, Akiyama Y, Hashi K. [Comparison of myelin-forming cells as candidates for therapeutic transplantation in demyelinated CNS axons]. Brain And Nerve 脳と神経 2000, 52: 609-15. PMID: 10934721.Peer-Reviewed Original ResearchConceptsDemyelinated CNS axonsSchwann cellsBrain cellsSpinal cordConduction velocityCNS axonsAdult rat spinal cordFronto-temporal lobesRat spinal cordAdult Schwann cellsDemyelination of axonsMyelin-forming cellsBlock of conductionAdult olfactoryDemyelinated diseasesDemyelinated axonsLess myelinationHistological examinationCNS tissueTherapeutic approachesStimulus trainsDay 28Transplanted OECsAmplitude decrementRemyelination