2013
Molecular Pathways: Induction of Polyploidy as a Novel Differentiation Therapy for Leukemia
Krause DS, Crispino JD. Molecular Pathways: Induction of Polyploidy as a Novel Differentiation Therapy for Leukemia. Clinical Cancer Research 2013, 19: 6084-6088. PMID: 23963861, PMCID: PMC3836832, DOI: 10.1158/1078-0432.ccr-12-2604.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaAcute megakaryocytic leukemiaAcute promyelocytic leukemiaDifferentiation therapyForms of AMLSpecific hematologic malignanciesAbnormal hematopoietic cellsTrans retinoic acidPolyploidy inducersTumor burdenMyelodysplastic syndromeHematologic malignanciesEffective therapyInduction of polyploidizationMyeloid leukemiaClinical studiesPromyelocytic leukemiaMegakaryocytic leukemiaPrimary myelofibrosisTherapyLeukemiaDifferentiation of megakaryocytesRetinoic acidMalignancySuch agents
1998
High-dose chemotherapy followed by reinfusion of selected CD34+ peripheral blood cells in patients with poor-prognosis breast cancer: a randomized multicentre study
Chabannon C, Cornetta K, Lotz J, Rosenfeld C, Shlomchik M, Yanovitch S, Marolleau J, Sledge G, Novakovitch G, Srour E, Burtness B, Camerlo J, Gravis G, Lee-Fischer J, Faucher C, Chabbert I, Krause D, Maraninchi D, Mills B, Kunkel L, Oldham F, Blaise D, Viens P. High-dose chemotherapy followed by reinfusion of selected CD34+ peripheral blood cells in patients with poor-prognosis breast cancer: a randomized multicentre study. British Journal Of Cancer 1998, 78: 913-921. PMID: 9764583, PMCID: PMC2063121, DOI: 10.1038/bjc.1998.601.Peer-Reviewed Original ResearchConceptsPoor prognosis breast cancerHigh-dose chemotherapyHaematopoietic recoveryBreast cancerRecombinant human granulocyte colony-stimulating factorBlood cellsRandomized multicentre studyGranulocyte colony-stimulating factorHuman granulocyte colony-stimulating factorPeripheral blood cellsPeripheral blood CD34Peripheral blood progenitorsColony-stimulating factorMobilized blood cellsEpithelial tumor cellsEligible patientsStudy armsMulticentre studyPeripheral bloodConventional chemotherapyStudy groupPatientsChemotherapyBlood CD34CD34