2024
Upper respiratory Streptococcus pneumoniae colonization among working-age adults with prevalent exposure to overcrowding
Parker A, Jackson N, Awasthi S, Kim H, Alwan T, Wyllie A, Kogut K, Holland N, Mora A, Eskenazi B, Riley L, Lewnard J. Upper respiratory Streptococcus pneumoniae colonization among working-age adults with prevalent exposure to overcrowding. Microbiology Spectrum 2024, 12: e00879-24. PMID: 39012111, PMCID: PMC11302326, DOI: 10.1128/spectrum.00879-24.Peer-Reviewed Original ResearchPneumococcal carriageStreptococcus pneumoniae</i>Pneumococcal diseaseLt;5 yearsPredictors of carriagePrecursor to pneumococcal diseaseAssociated with increased riskRisk of carriageExposure to childrenYoung childrenExposure to young childrenCycle threshold valuesPneumococcal densityVulnerable age groupRisk factorsPneumococcal transmissionIncreased prevalenceNon-carriersPneumococciAge groupsCarriageSaliva samplesAdult populationMilitary recruitsQuantitative PCR assay
2021
1321. Acquisition and Transmission of Streptococcus pneumoniae in Individuals Over the Age of 60 Years Residing in New Haven, CT, USA
Wyllie A, Mbodj S, Yolda-Carr D, Thammavongsa D, Waghela P, Nakahata M, Vega N, York A, Allicock O, Alexander-Parrish R, Arguedas A, Gessner B, Weinberger D, Hislop M. 1321. Acquisition and Transmission of Streptococcus pneumoniae in Individuals Over the Age of 60 Years Residing in New Haven, CT, USA. Open Forum Infectious Diseases 2021, 8: 749-749. PMCID: PMC8689704, DOI: 10.1093/ofid/ofab466.1513.Peer-Reviewed Original ResearchPneumococcal carriageSaliva samplesOlder adultsPreventative public health measuresPneumococcal conjugate vaccineNew Haven areaPublic health measuresPneumococcal acquisitionPneumococcal diseaseConjugate vaccinePneumococcal transmissionStudy enrollmentMedical historyImportant burdenDemonstrate evidenceStreptococcus pneumoniaeHealth measuresMultiple timepointsTime pointsWeeksAdultsCOVID-19 pandemicAgeHigh ratePneumococci
2020
Upper respiratory tract colonization with Streptococcus pneumoniae in adults
Arguedas A, Trzciński K, O’Brien K, Ferreira DM, Wyllie AL, Weinberger D, Danon L, Pelton SI, Azzari C, Hammitt LL, Sá-Leão R, Brandileone MC, Saha S, Suaya J, Isturiz R, Jodar L, Gessner BD. Upper respiratory tract colonization with Streptococcus pneumoniae in adults. Expert Review Of Vaccines 2020, 19: 353-366. PMID: 32237926, DOI: 10.1080/14760584.2020.1750378.Peer-Reviewed Original ResearchConceptsPediatric approachPneumococcal colonizationPneumococcal detectionRespiratory sitesUpper respiratory tract colonizationAdult respiratory tractRespiratory tract colonizationHigh disease burdenPneumococcal carriage studiesRespiratory carriageNasal washesPeer-reviewed journalsRespiratory colonizationCarriage prevalencePneumococcal transmissionTract colonizationDisease burdenRespiratory tractCarriage studiesCurrent evidenceStreptococcus pneumoniaeMolecular diagnostic methodsRoutine cultureAdultsRecent evidence