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With Cellular Blueprint for Lungs, Yale Researchers Look Ahead to Organ Regeneration
Using sophisticated screening across animal species, researchers at Yale have created a cellular blueprint of the human lung that will make it easier to understand the design principles behind lung function and disease — and to bioengineer new lungs.
The research, published Dec. 4 in Science Advances, represents a collaboration between two Yale labs — that of Naftali Kaminski, M.D., chief of pulmonary, critical care, and sleep medicine at Yale School of Medicine, and Laura Niklason, M.D., Ph.D., the Nicholas Greene Professor of anesthesiology and biomedical engineering and an expert in stimulating growth of new lung tissue from the body’s own cells for use in transplants.