Statin-induced mitochondrial priming sensitizes multiple myeloma cells to BCL2 and MCL1 inhibitors
Juarez D, Buono R, Matulis S, Gupta V, Duong M, Yudiono J, Paul M, Mallya S, Diep G, Hsin P, Lu A, Suh S, Dong V, Roberts A, Leverson J, Jalaluddin M, Liu Z, Bueno O, Boise L, Fruman D. Statin-induced mitochondrial priming sensitizes multiple myeloma cells to BCL2 and MCL1 inhibitors. Cancer Research Communications 2023, 3: 2497-2509. PMID: 37956312, PMCID: PMC10704957, DOI: 10.1158/2767-9764.crc-23-0350.Peer-Reviewed Original ResearchAntineoplastic AgentsHematologic NeoplasmsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMultiple MyelomaMyeloid Cell Leukemia Sequence 1 ProteinProspective StudiesProto-Oncogene Proteins c-bcl-2Retrospective Studies