2024
Immune microenvironmental heterogeneity according to tumor DNA methylation phenotypes in microsatellite instability-high colorectal cancers
Kim J, Hong J, Lee J, Jung M, Choi E, Cho N, Kang G, Kim S. Immune microenvironmental heterogeneity according to tumor DNA methylation phenotypes in microsatellite instability-high colorectal cancers. Cancer Immunology, Immunotherapy 2024, 73: 215. PMID: 39235590, PMCID: PMC11377388, DOI: 10.1007/s00262-024-03805-3.Peer-Reviewed Original ResearchConceptsProgrammed death-ligand 1Tumor-infiltrating lymphocytesMicrosatellite instability-high colorectal cancerCombined positive scoreTumor proportion scoreTumor mutational burdenCD8+ tumor-infiltrating lymphocytesMicrosatellite instability-highTumor-infiltrating immune cellsCpG island methylator phenotypeColorectal cancerCIMP-high tumorsDensity of CD8+ tumor-infiltrating lymphocytesProgrammed death-ligand 1 tumor proportion scoreCIMP-highConsensus molecular subtype 1Cytolytic activity scoreWhole-slide immunohistochemistryDeath-ligand 1Tumor immune microenvironmentMethylator phenotypeMicrosatellite instability-high tumorsTumor DNA methylationDNA methylation phenotypeCpG island methylator phenotype status
2011
Characteristics of an Explosive Blast-Induced Brain Injury in an Experimental Model
de Lanerolle NC, Bandak F, Kang D, Li AY, Du F, Swauger P, Parks S, Ling G, Kim JH. Characteristics of an Explosive Blast-Induced Brain Injury in an Experimental Model. Journal Of Neuropathology & Experimental Neurology 2011, 70: 1046-1057. PMID: 22002430, DOI: 10.1097/nen.0b013e318235bef2.Peer-Reviewed Original ResearchConceptsBrain injuryAxonal injuryΒ-amyloid precursor protein immunohistochemistryAnesthetized Yorkshire swineBlast-Induced Brain InjuryMild traumatic brain injuryPrecursor protein immunohistochemistryTraumatic brain injuryBlast injury modelAstrocyte activationNeuronal injuryNeuropathologic changesIntracranial hemorrhageNeuropathologic consequencesProtein immunohistochemistryHistologic changesNeurobehavioral outcomesInjury modelPathologic changesSham controlsMood disordersInjuryYorkshire swineExperimental modelHuman brain
2001
Pathology of epilepsy.
Kim JH. Pathology of epilepsy. Experimental And Molecular Pathology 2001, 70: 345-67. PMID: 11418013, DOI: 10.1006/exmp.2001.2372.Peer-Reviewed Original Research
1999
Differential Neuronal and Glial Relations with Parameters of Ictal Discharge in Mesial Temporal Lobe Epilepsy
Spencer S, Kim J, DeLanerolle N, Spencer D. Differential Neuronal and Glial Relations with Parameters of Ictal Discharge in Mesial Temporal Lobe Epilepsy. Epilepsia 1999, 40: 708-712. PMID: 10368067, DOI: 10.1111/j.1528-1157.1999.tb00767.x.Peer-Reviewed Original ResearchConceptsGlial densityTemporal lobe epilepsyNeuronal densitySpontaneous seizuresLobe epilepsyIctal dischargesSeizure onsetMesial temporal lobe epilepsyElectrical seizure durationHippocampal seizure onsetPercentage of seizuresInterictal-ictal transitionEEG recordingsSeizure durationSeizure parametersPatient's seizuresSeizure propagationPathologic analysisHippocampal fieldsEpilepsy pathogenesisIntracranial EEG recordingsTL resectionSeizuresSynaptic changesPatients
1990
Verbal memory impairment correlates with hippocampal pyramidal cell density.
Sass K, Spencer D, Kim J, Westerveld M, Novelly R, Lencz T. Verbal memory impairment correlates with hippocampal pyramidal cell density. Neurology 1990, 40: 1694-7. PMID: 2234424, DOI: 10.1212/wnl.40.11.1694.Peer-Reviewed Original ResearchConceptsTemporal seizure focusSeizure focusMemory impairmentSurgical removalMesial temporal lobe structuresMesial temporal structuresPyramidal cell densityGranule cell layerHippocampal subfields CA1Temporal lobe structuresVerbal memory impairmentRefractory epilepsySelective Reminding TestHilar areaImpairment correlatesTemporal lobeBlinded observersSubfields CA1Cell countArea dentataVolumetric cell densityPatientsLobe structuresImpairmentVerbal Selective Reminding Test
Others
- Wong, J.H., Kim, J.H., Awad, I.A. Pathological features of spinal vascular malformations. (Chapter 2). In:Spinal vascular malformations. Barrow, D.L. and Awad, I.A. (eds). Am. Assoc. Neurol. Surgeons, Park Ridge, pp9-22, 1999.Peer-Reviewed Original Research
- Hatanpaa, KJ, Kim JH. Neuropathology of Viral Infections (Chapter 8) in Handbook of Clinical Neurology, Vol. 123 (3rd Series), Aminoff, M, Boller, R and Swaab, D (eds), Tselis AC & Booss, J. (Volume Eds) Elsevier, 175-192, 2014Peer-Reviewed Original Research