2017
Clinicopathologic and outcome study of sessile serrated adenomas/polyps with serrated versus intestinal dysplasia
Cenaj O, Gibson J, Odze RD. Clinicopathologic and outcome study of sessile serrated adenomas/polyps with serrated versus intestinal dysplasia. Modern Pathology 2017, 31: 633-642. PMID: 29271414, DOI: 10.1038/modpathol.2017.169.Peer-Reviewed Original ResearchConceptsSessile serrated adenomas/polypsSerrated adenomas/polypsAdenomas/polypsIntestinal dysplasiaConventional adenomasSerrated dysplasiaPrevalence of adenocarcinomaType of dysplasiaHigh-grade lesionsDysplasia-carcinoma sequenceLow-grade dysplasiaNeoplastic precursor lesionsHigh rateDysplasia subtypeControl patientsPathologic featuresMean ageMicrosatellite unstable cancersBiologic featuresInvasive carcinomaPrecursor lesionsNeoplastic lesionsPrevalence ratesOutcome studiesPatients
2015
Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use
Sethi A, Jain D, Roland BC, Kinzel J, Gibson J, Schrader R, Hanson JA. Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use. Archives Of Pathology & Laboratory Medicine 2015, 139: 225-32. PMID: 25611105, DOI: 10.5858/arpa.2013-0594-oa.Peer-Reviewed Original ResearchConceptsHigh-power fieldMC countChronic diarrheaMast cell countsUnknown etiologyMast cellsCutoff valueMastocytic enterocolitisLeft colonBiopsy resultsClinical utilityDiscriminatory cutoff valuesCell countC-kit stainConsecutive control patientsMast cell stabilizerSpecific cutoff valuesSingle high-power fieldControl patientsConsecutive patientsNormal biopsiesCell stabilizerCharacteristic analysisStudy groupSpecial stains