Familial Aggregation of Insulin Resistance in First-Degree Relatives of Patients With Nonalcoholic Fatty Liver Disease
Abdelmalek M, Liu C, Shuster J, Nelson D, Asal N. Familial Aggregation of Insulin Resistance in First-Degree Relatives of Patients With Nonalcoholic Fatty Liver Disease. Clinical Gastroenterology And Hepatology 2006, 4: 1162-1169. PMID: 16901766, DOI: 10.1016/j.cgh.2006.06.001.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseFirst-degree relativesFatty liver diseaseCryptogenic cirrhosisDiabetes mellitusLiver diseaseGenetic predispositionRisk of DMFamilial clusteringFirst-degree family membersBody mass indexInsulin resistance syndromeSignificant survival differenceExpression of IRWarrants further investigationNAFLD patientsMass indexResistance syndromeInsulin resistanceMedical historySurvival differencesHealthy controlsCardiac diseaseRenal stonesFamilial aggregation studies