Allison Didychuk, PhD
she/her/hers
Assistant ProfessorCards
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Research
Publications
2026
Something old, something new? Herpesvirus genome packaging examined in light of lessons from the tailed bacteriophages.
Meißner L, Shiah J, Adeyemi O, Bailey E, Gelles-Watnick S, Didychuk A. Something old, something new? Herpesvirus genome packaging examined in light of lessons from the tailed bacteriophages. Journal Of Virology 2026, e0178525. PMID: 42405778, DOI: 10.1128/jvi.01785-25.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2025
The Kaposi’s sarcoma-associated herpesvirus TBP mimic uses a noncanonical DNA-binding mode to promote viral late gene transcription
Llacsahuanga-Allcca L, Didychuk A, Rodríguez-Vargas A, Glaunsinger B. The Kaposi’s sarcoma-associated herpesvirus TBP mimic uses a noncanonical DNA-binding mode to promote viral late gene transcription. Nucleic Acids Research 2025, 53: gkaf1008. PMID: 41099709, PMCID: PMC12529657, DOI: 10.1093/nar/gkaf1008.Peer-Reviewed Original Research
2023
The viral packaging motor potentiates Kaposi’s sarcoma-associated herpesvirus gene expression late in infection
McCollum C, Didychuk A, Liu D, Murray-Nerger L, Cristea I, Glaunsinger B. The viral packaging motor potentiates Kaposi’s sarcoma-associated herpesvirus gene expression late in infection. PLOS Pathogens 2023, 19: e1011163. PMID: 37068108, PMCID: PMC10138851, DOI: 10.1371/journal.ppat.1011163.Peer-Reviewed Original Research
2022
DNA processing by the Kaposi's sarcoma-associated herpesvirus alkaline exonuclease SOX contributes to viral gene expression and infectious virion production
Hartenian E, Mendez A, Didychuk A, Khosla S, Glaunsinger B. DNA processing by the Kaposi's sarcoma-associated herpesvirus alkaline exonuclease SOX contributes to viral gene expression and infectious virion production. Nucleic Acids Research 2022, 51: 182-197. PMID: 36537232, PMCID: PMC9841436, DOI: 10.1093/nar/gkac1190.Peer-Reviewed Original ResearchBetter late than never: A unique strategy for late gene transcription in the beta- and gammaherpesviruses
Dremel S, Didychuk A. Better late than never: A unique strategy for late gene transcription in the beta- and gammaherpesviruses. Seminars In Cell And Developmental Biology 2022, 146: 57-69. PMID: 36535877, PMCID: PMC10101908, DOI: 10.1016/j.semcdb.2022.12.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThe transition phase: preparing to launch a laboratory
McKinley K, Didychuk A, Nicholas D, Termini C. The transition phase: preparing to launch a laboratory. Trends In Biochemical Sciences 2022, 47: 814-818. PMID: 35644775, PMCID: PMC9677455, DOI: 10.1016/j.tibs.2022.05.002.Peer-Reviewed Original ResearchA Two-tiered functional screen identifies herpesviral transcriptional modifiers and their essential domains
Morgens D, Nandakumar D, Didychuk A, Yang K, Glaunsinger B. A Two-tiered functional screen identifies herpesviral transcriptional modifiers and their essential domains. PLOS Pathogens 2022, 18: e1010236. PMID: 35041709, PMCID: PMC8797222, DOI: 10.1371/journal.ppat.1010236.Peer-Reviewed Original Research
2021
A pentameric protein ring with novel architecture is required for herpesviral packaging
Didychuk A, Gates S, Gardner M, Strong L, Martin A, Glaunsinger B. A pentameric protein ring with novel architecture is required for herpesviral packaging. ELife 2021, 10: e62261. PMID: 33554858, PMCID: PMC7889075, DOI: 10.7554/elife.62261.Peer-Reviewed Original Research
2020
The gammaherpesviral TATA-box-binding protein directly interacts with the CTD of host RNA Pol II to direct late gene transcription
Castañeda A, Didychuk A, Louder R, McCollum C, Davis Z, Nogales E, Glaunsinger B. The gammaherpesviral TATA-box-binding protein directly interacts with the CTD of host RNA Pol II to direct late gene transcription. PLOS Pathogens 2020, 16: e1008843. PMID: 32886723, PMCID: PMC7498053, DOI: 10.1371/journal.ppat.1008843.Peer-Reviewed Original ResearchConserved CxnC Motifs in Kaposi’s Sarcoma-Associated Herpesvirus ORF66 Are Required for Viral Late Gene Expression and Are Essential for Its Interaction with ORF34
Didychuk A, Castañeda A, Kushnir L, Huang C, Glaunsinger B. Conserved CxnC Motifs in Kaposi’s Sarcoma-Associated Herpesvirus ORF66 Are Required for Viral Late Gene Expression and Are Essential for Its Interaction with ORF34. Journal Of Virology 2020, 94: 10.1128/jvi.01299-19. PMID: 31578296, PMCID: PMC6955276, DOI: 10.1128/jvi.01299-19.Peer-Reviewed Original Research
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Didychuk Lab - Bass 413
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Bass Center
266 Whitney Avenue
New Haven, CT 06511
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Oct 20265Monday
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