Jeanne Hendrickson, MD
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Appointments
Laboratory Medicine
Primary
General Pediatrics
Secondary
Contact Info
Laboratory Medicine
330 Cedar Street, PO Box 208035
New Haven, CT 06520-8035
United States
About
Titles
Professor Adjunct
Biography
Dr. Hendrickson is a pediatric hematologist and transfusion medicine specialist. Her clinical interests include factors influencing alloimmunization (particularly red blood cell alloimmunization), as well as strategies to minimize the formation and dangers of such antibodies. Her translational research interests include investigating the induction and consequences of red blood cell alloantibodies in transfusion and pregnancy situations, in murine models and in the clinical setting.
Appointments
Laboratory Medicine
Professor AdjunctPrimaryGeneral Pediatrics
ProfessorSecondary
Other Departments & Organizations
- Blood Bank
- Cancer Immunology
- General Pediatrics
- Laboratory Medicine
- Laboratory Medicine - Education
- Yale Center for Immuno-Oncology
- YCCEH
Education & Training
- Fellowship
- Emory School of Medicine (2008)
- Fellowship
- Emory University School of Medicine (2007)
- Residency
- Emory University School of Medicine (2002)
- MD
- Emory University School of Medicine (1999)
- BS
- University of North Carolina @ Chapel Hill (1994)
Research
Overview
Please pubmed search Hendrickson JE to see the range of topics the Hendrickson lab is interested in. In general, the lab is interested in investigating clinically relevant issues in transfusion medicine using basic science models and translational research tools.
Cellular therapy; Red blood cell alloimmunization
Medical Subject Headings (MeSH)
Anemia, Sickle Cell; Blood Transfusion; Hematology; Immune Tolerance; Immunity, Humoral; Plasmapheresis; Pregnancy Complications, Hematologic; Transfusion Medicine
ORCID
0000-0002-7928-3132
Research at a Glance
Yale Co-Authors
Frequent collaborators of Jeanne Hendrickson's published research.
Publications Timeline
A big-picture view of Jeanne Hendrickson's research output by year.
Research Interests
Research topics Jeanne Hendrickson is interested in exploring.
Ronald George Hauser III, MD
Oliver Karam, MD, PhD
Alexa Siddon, MD
Alfred Lee, MD, PhD
John D Roberts, MD
Raisa Balbuena-Merle, MD, MHS
135Publications
687Citations
Blood Transfusion
Anemia, Sickle Cell
Hematology
Immune Tolerance
Publications
2024
Optimizing autologous stem cell collections for patients with multiple myeloma receiving G‐CSF and Plerixafor: A single center project
Javanbakht A, Stringer S, Anderson H, Hamilton E, Philip A, Waller E, Langston A, Joseph N, Roback J, Schneider T, Sullivan H, Hendrickson J. Optimizing autologous stem cell collections for patients with multiple myeloma receiving G‐CSF and Plerixafor: A single center project. Journal Of Clinical Apheresis 2024, 39: e22127. PMID: 38803152, DOI: 10.1002/jca.22127.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsMeSH KeywordsAdultAgedBenzylaminesBlood Component RemovalCyclamsFemaleGranulocyte Colony-Stimulating FactorHematopoietic Stem Cell MobilizationHeterocyclic CompoundsHumansMaleMiddle AgedMultiple MyelomaPeripheral Blood Stem Cell TransplantationPlatelet CountRetrospective StudiesTransplantation, AutologousConceptsStem cell collectionPlatelet countG-CSFMultiple myelomaAutologous peripheral blood stem cell collectionApheresis collectionsPeripheral blood stem cell collectionAutologous stem cell collectionBlood stem cell collectionCell collectionPre-emptive plerixaforBaseline platelet countTransplant doseAutologous collectionApheresisPatientsMedical recordsPlerixaforCollection goalDay of collectionQuality improvement initiativesMyelomaPoor mobilityPlateletCountHow I treat challenging transfusion cases in sickle cell disease
Chou S, Hendrickson J. How I treat challenging transfusion cases in sickle cell disease. Blood 2024 PMID: 38728382, DOI: 10.1182/blood.2023023648.Peer-Reviewed Original ResearchAltmetricConceptsDelayed hemolytic transfusion reactionSickle cell diseaseRed blood cellsTransfusion of red blood cellsRed blood cell alloantibodiesRed blood cell transfusionCell diseaseHemolytic transfusion reactionsManagement of complicationsAlloimmunized patientsRh alloimmunizationCurative therapyTransfusion guidelinesTransfusion recipientsClinical dilemmaFuture transfusionsTransfusionPatient populationTransfusion casesTransfusion reactionsBlood donorsRH variantsBlood cellsAlloimmunizationMedicine providersRed blood cell alloimmunization in patients on extracorporeal membrane oxygenation
Javanbakht A, Schneider T, Hendrickson J. Red blood cell alloimmunization in patients on extracorporeal membrane oxygenation. Transfusion 2024, 64: 761-762. PMID: 38593282, DOI: 10.1111/trf.17761.Peer-Reviewed Original ResearchDevelopment and evaluation of trigger tools to identify pediatric blood management errors.
Kandaswamy S, Josephson C, Rollins M, Jones J, Zerra P, Goel R, Andrews J, Hendrickson J, Lieberman L, Orenstein E. Development and evaluation of trigger tools to identify pediatric blood management errors. Blood Transfusion = Trasfusione Del Sangue 2024 PMID: 38557324, DOI: 10.2450/bloodtransfus.606.Peer-Reviewed Original ResearchConceptsElectronic health recordsAutomated trigger toolsTrigger ToolQueries of electronic health recordsPositive patient identificationPediatric health systemPositive predictive valueRAND-UCLA methodSurveillance systemHealth recordsAdverse eventsPassive surveillance methodsHealth systemPediatric environmentPassive surveillance systemPatient identificationActive surveillance systemNear missesMiss eventsExpert panelMedicine specialistsPatient blood managementOver-transfusionManual reviewManagement errors735 Human milk fortification and intestinal inflammation in very preterm infants
Salem A, Ou J, Lukemire J, Shenvi N, Barbian M, Rose A, Hendrickson J, Easley K, Guo Y, Arthur C, Stowell S, Josephson C, Patel R. 735 Human milk fortification and intestinal inflammation in very preterm infants. The American Journal Of The Medical Sciences 2024, 367: s459-s460. DOI: 10.1016/s0002-9629(24)00785-7.Peer-Reviewed Original ResearchDecreasing alloimmunization‐specific mortality in sickle cell disease in the United States: Cost‐effectiveness of a shared transfusion resource
Ito S, Pandya A, Hauser R, Krishnamurti L, Stites E, Tormey C, Krumholz H, Hendrickson J, Goshua G. Decreasing alloimmunization‐specific mortality in sickle cell disease in the United States: Cost‐effectiveness of a shared transfusion resource. American Journal Of Hematology 2024, 99: 570-576. PMID: 38279581, DOI: 10.1002/ajh.27211.Peer-Reviewed Original ResearchAltmetricConceptsSickle cell diseaseDelayed hemolytic transfusion reactionQuality-adjusted life expectancyAlloimmunized patientsPatient populationRed blood cell alloimmunizationCell diseaseCost-effective interventionMedical expenditure of patientsHealth system perspectiveExpenditure of patientsIncremental cost-effectiveness ratioHemolytic transfusion reactionsUnited StatesMarkov cohort simulationCost-effectiveAverage patient populationCost-effectiveness ratioBirth cohortAnalytical time horizonAntibody historyCohort simulationTransfusionTransfusion reactionsLife expectancyChapter 7 Consent and an approach to the management of acute and chronic transfusion reactions
Hendrickson J, Lieberman L. Chapter 7 Consent and an approach to the management of acute and chronic transfusion reactions. 2024, 113-124. DOI: 10.1016/b978-0-323-90459-9.00006-2.Peer-Reviewed Original Research
2023
P‐CB‐23 | Transfused RBCs Are Weak Inducers of IgG Class‐Switching Due to Inefficient Induction of CD4+ T‐Cell Help
Medved J, Shah N, Hester B, Burnett E, Boscia A, Niebuhr C, Santhanakrishnan M, Zimring J, Hendrickson J, Luckey C. P‐CB‐23 | Transfused RBCs Are Weak Inducers of IgG Class‐Switching Due to Inefficient Induction of CD4+ T‐Cell Help. Transfusion 2023, 63: 161a-161a. DOI: 10.1111/trf.206_17554.Peer-Reviewed Original ResearchP‐CB‐21 | RBC Alloimmunization Responder Type and COVID‐19 Vaccine IgG Response in Patients with Sickle Cell Disease
Nakahara H, Cheedarla N, Verkerke H, Cheedarla S, Wu S, Hendrickson J, Roback J, Neish A, Fasano R, Stowell S. P‐CB‐21 | RBC Alloimmunization Responder Type and COVID‐19 Vaccine IgG Response in Patients with Sickle Cell Disease. Transfusion 2023, 63: 159a-160a. DOI: 10.1111/trf.204_17554.Peer-Reviewed Original ResearchAntibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression
Jajosky R, Patel K, Allen J, Zerra P, Chonat S, Ayona D, Maier C, Morais D, Wu S, Luckey C, Eisenbarth S, Roback J, Fasano R, Josephson C, Manis J, Chai L, Hendrickson J, Hudson K, Arthur C, Stowell S. Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression. Blood 2023, 142: 1082-1098. PMID: 37363865, PMCID: PMC10541552, DOI: 10.1182/blood.2022018591.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAntibody-mediated immunosuppressionRBC alloantigensImmune responseFetal red blood cell antigensTarget antigenRed blood cell antigensRh immune globulinMaternal immune responseBlood cell antigensInclusion of antibodiesRBC removalAnti-RhD antibodiesAbility of antibodiesImmune globulinAntibody responseHemolytic diseaseRBC clearanceCell antigensFetal RBCsAntibody characteristicsAlloantigensSimilar interventionsAntibodiesAntigenPolyclonal antibody preparation
Links & Media
News
- April 09, 2024
Laboratory Medicine Faculty honored as AABB 2023 President's Award Recipients
- August 11, 2021
Discoveries & Impact (August 2021)
- December 05, 2020
Yale Cancer Center Study Shows Caplacizumab Not Cost Effective for Rare Blood Disorder
- May 26, 2020
2020 Rise Award Winner and ACLPS Ellis Benson Award Winner, Jeanne Hendrickson, MD
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Academic Office Number
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Mailing Address
Laboratory Medicine
330 Cedar Street, PO Box 208035
New Haven, CT 06520-8035
United States