The overarching goal of this Enrichment Program is to enhance scientific knowledge exchange among investigators currently involved in, or wishing to become involved in, NIDDK hematology research relevant areas.
Yale Cooperative Center of Excellence in Hematology (YCCEH)
The purpose of the Yale Cooperative Center of Excellence in Hematology is to enhance research in blood diseases by facilitating synergy between many different scientists both within Yale and at multiple academic institutions across the country.
The Center helps these scientists by providing access to and training in state-of-the-art technologies via 3 Technology Cores, Pilot and Feasibility Funding, and an Enrichment Program. Our unique focus is the application of emerging technologies to better understand blood diseases. The center plays a key role in the integrated program of blood disease research supported by other Cooperative Hematology Specialized Core Centers by providing opportunities to increase interactions and collaborations.
Cores
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YCCEH Enrichment Core Cell Preparation and Analysis Core The Cell Preparation and Analysis Core provides essential and emerging technologies in hematology and relevant training for junior investigators, thus considerably increasing research efficiency, reducing expense, and saving valuable investigator time to achieve better advancement of hematologic research.Read MoreAnimal Modeling Core The Animal Modeling Core provides access to state of the art technologies for in vivo Hematology research. Specifically, this core provides access to immunodeficient mouse models for engraftment of primary human cells, and state of the art technologies to generate genetically modified mice, as well as teaching, expertise, and technical support for the study of hematopoiesis and hematologic questions in in vivo mouse models.Read MoreImaging Core The Imaging Core provides access to and training in the use of imaging technology in hematology both locally and nationally.Read More
Faculty Spotlight
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Trainee Spotlight
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Manuscript Spotlight
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- Cell surface RNAs control neutrophil recruitment.Zhang N, Tang W, Torres L, Wang X, Ajaj Y, Zhu L, Luan Y, Zhou H, Wang Y, Zhang D, Kurbatov V, Khan SA, Kumar P, Hidalgo A, Wu D, Lu J. Cell. 2024 Feb 15; 2024 Jan 22. PMID: 38262409.
- Spatial profiling of chromatin accessibility in mouse and human tissues.Deng Y, Bartosovic M, Ma S, Zhang D, Kukanja P, Xiao Y, Su G, Liu Y, Qin X, Rosoklija GB, Dwork AJ, Mann JJ, Xu ML, Halene S, Craft JE, Leong KW, Boldrini M, Castelo-Branco G, Fan R. Nature. 2022 Sep; 2022 Aug 17. PMID: 35978191.
- Inflammasome activation in infected macrophages drives COVID-19 pathology.Sefik E, Qu R, Junqueira C, Kaffe E, Mirza H, Zhao J, Brewer JR, Han A, Steach HR, Israelow B, Blackburn HN, Velazquez SE, Chen YG, Halene S, Iwasaki A, Meffre E, Nussenzweig M, Lieberman J, Wilen CB, Kluger Y, Flavell RA. Nature. 2022 Jun; 2022 Apr 28. PMID: 35483404.
- Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells.Song Y, Shan L, Gbyli R, Liu W, Strowig T, Patel A, Fu X, Wang X, Xu ML, Gao Y, Qin A, Bruscia EM, Tebaldi T, Biancon G, Mamillapalli P, Urbonas D, Eynon E, Gonzalez DG, Chen J, Krause DS, Alderman J, Halene S, Flavell RA. Science. 2021 Mar 5. PMID: 33674488.
- The N-glycome regulates the endothelial-to-hematopoietic transition.Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S. Science. 2020 Dec 4; 2020 Dec 3. PMID: 33273096.
YCCEH Events
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Jan 202614Wednesday
Everyone Nicholas Scott Heaton, PhD
Jan 202616Friday
Everyone Zuzana Tothova, MD, PhD
Jan 202621Wednesday
Everyone Margaret Scull, PhD
Feb 20269Monday
Yale Only Craig Morrell, DVM, PhD
Feb 202618Wednesday
Everyone Harold K. Elias, MD
Feb 202620Friday
Everyone Shannon Elf, PhD
Mar 20263Tuesday
Yale Only Jennifer Zenker
Mar 202620Friday
Everyone Speakers to be announced.
Apr 202615Wednesday
Everyone John MacMicking, PhD
Apr 202617Friday
Everyone Speakers to be announced.
Latest News
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- December 16, 2025
Yale Cancer Center Research in Breast Cancer and Hematology Showcased at National Meetings
- December 15, 2025
The Future of Medicine: Physician-Scientists and Mentorship
- December 09, 2025
Yale research advances presented at American Society of Hematology annual meeting
- November 12, 2025
Twenty-Seven YSM Faculty Members Recognized for Highly Cited Research