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YCCEH Pilot and Feasibility Program

A central Pilot and Feasibility program directly administered by NIDDK is now open. Details of the central P&F program can be found at Applications are due on a rolling basis.

Questions about the YCCEH P&F Program, please contact:

YCCEH P&F Awardees and Project Titles

YCCEH Internal P&F Awardees


Ellen Foxman PhD
Assistant Professor, Laboratory Medicine

Defining neutrophil phenotype induced by viral respiratory infection

Vanessa Scanlon PhD
Instructor, Laboratory Medicine

Intercellular Communication Mechanisms between MEP and Bone Marrow-Derived Macrophages that Regulate MEP Fate.

Yuanbin Song PhD
Associate Research Scientist, Medicine (Hematology)

In Vivo Reconstruction of Human Erythropoiesis with Circulating Mature Human RBCs in Humanized Liver Mice


Abhishek Gupta, PhD
Associate Research Scientist, Hematology, Yale Cancer Center.

Molecular Mechanisms underlying ring sideroblast (RS) morphology in SF3B1-mutant Myelodysplastic Syndrome (MDS).

Samuel Katz, MD, PhD
Associate Professor of Pathology

Elucidation of hematopoietic niches by single-cell in situ transcriptome analysis.

Toma Tebaldi, PhD
Associate Research Scientist, Hematology, Yale Cancer Center.

Understanding how RNA methylation shapes hematopoiesis.


Gary Kupfer, MD
Professor of Pediatrics (Hematology / Oncology) and Pathology

Characterization of the function of MACF1, the gene mutated in a variant of congenital dyserythropoietic anemia IV.

Karla Neugebauer, PhD
Professor of Molecular Biophysics and Biochemistry and Cell Biology.

Thalassemia and the kinetics of globin gene expression with single molecule RNA-Seq.

Richard Torres, MD, MS
Assistant Professor of Laboratory Medicine and Lecturer in Molecular Biophysics and Biochemistry.

Deep high resolution imaging of spleen and bone marrow histology with concurrent fluorescent in situ hybridization.


Jackie Fretz, PhD
Assistant Professor of Orthopaedics and Rehabilitation

A Novel Mouse Model of the Anemia of Renal Failure.

Shilpa Hattangadi, MD
Assistant Professor of Pediatrics (Hematology/Oncology)

4-D Nucleome of the Developing Erythroblast Nucleus: How long-noncoding RNAs (lncRNAs) help regulate erythroid nuclear condensation via dynamic changes.

Jeanne Hendrickson, MD
Associate Professor of Laboratory Medicine and Pediatrics

An Investigation of Red Blood Cell Antigen Modulation.

Yi-Chien Lu, PhD
Associate Research Scientist in Laboratory Medicine

Novel Pathway Promoting Megakaryocyte and Erythroid Commitment.


Emanuela Bruscia, PhD
Assistant Professor of Pediatrics (Pulmonary)

Understanding myeloid cell dysfunction in cystic fibrosis.

Shangqin Guo, PhD
Assistant Professor of Cell Biology

A novel genetic regulator of hematopoietic stem cell reconstitution.

Jun Lu, PhD
Associate Professor of Genetics

The role of chronic inflammation on clonal selection of hematopoietic stem cells.

Manoj M. Pillai, MD
Assistant Professor of Medicine (Hematology)

Defining enhancer elements in the hematopoietic niche.

Partner P&F Awardees


Dionna Kasper, PhD
Postdoctoral Fellow, Cardiology

Defining novel miRNA-regulated mechanisms governing HSPC specification

Karin Finberg, MD, PhD
Assistant Professor of Pathology

Defining the relationship between iron status and dietary-induced obesity using Tmprss6 deficient mice

Sergei Doulatov, PhD
Assistant Professor of Medicine, University of Washington, Seattle, WA

Modeling of nonmalignant blood disorders using induced pluripotent stem cells

External P&F Awardees


Linda Resar MD
Professor of Medicine, Johns Hopkins University

HMGA1 Chromatin Regulators in Regenerative Capacity of Human Hematopoietic Stem Cells (YCCEH core usage)

Vanessa Scanlon PhD
Instructor, Department of Laboratory Medicine, Yale School of Medicine

The Role of Intercellular Communication between Bone Marrow Niche Cells and Megakaryocytic-Erythroid Progenitors (The Fred Hutchinson Cancer Research Center core usage)


Simona Colla PhD
Associate Professor, Department of Leukemia, MDACC

Tracking myelodysplastic syndrome cells of origin using humanized immuno-deficient mice.


Antonin Bourdieu PhD
Postdoctoral Fellow, Yale University, New Haven, CT

Fetal bone marrow niche development and its regulation by osteolineage cells.

Jeffrey Barminko PhD
Associate Scientist, Mount Sinai School of Medicine, New York, NY

Identification of hematopoietic progenitor cell and gene targets of the ligand-activated Vdr transcription factor using single cell transcriptomics

Priti Azad PhD
Associate Project Scientist, University of California San Diego, San Deigo, CA

Molecular Basis of Hypoxia-Induced Excessive Erythrocytosis: Critical Role of SNP/s in the SENP1 gene regulation