Skip to Main Content

Yale Liver Center

The Yale Liver Center is one of 17 Digestive Diseases Research Core Centers (DDRCCs) supported by NIH/NIDDK. The Yale Liver Center has been funded since 1984 and is one of only three that focus on the liver. The Yale Liver Center supports investigation of liver structure, function and disease. Research support is provided through the Center’s Four Core Facilities, as well as through Pilot Feasibility Projects that are offered annually and an Enrichment Program.

The research base is focused on three major basic/translational themes:

  • Hepatic metabolism
  • Immunobiology and inflammation
  • Liver cell biology/pathobiology

Currently, 43 independent principal investigators are Full Members of the Center as well as 52 Associate Members, which involves 30 departments and sections at Yale.

The Liver Center also supports weekly research seminars (on Tuesday afternoons) and clinical lectures (on Friday afternoons), in conjunction with the Section of Digestive Diseases, Department of Internal Medicine.

Directors

  • Co-Director, Yale Liver Center

    Gladys Phillips Crofoot Professor of Medicine (Digestive Diseases) and Professor of Cell Biology; Co-Director, Yale Liver Center, Digestive Diseases; Director, Center for Cell and Molecular Imaging

The Research Base

The Research Base can be organized to reflect the fact that it is focused on three major basic/translational themes.

These include:

  1. Hepatic metabolism
  2. Immunobiology and inflammation
  3. Liver cell biology/pathobiology.

The major areas of liver disease examined within these translational themes include autoimmune diseases, cholestasis, fibrosis/cirrhosis, genetic diseases, infections, pre-neoplastic conditions, and MASLD. Many of our investigators have research interests that span multiple themes.

Publication Acknowledgment

To cite the Liver Center in your publications please use the following statement:

”This project was supported in part by the Yale Liver Center award NIH P30 DK034989 ________ core.”
(insert name of core(s) that you used-Morphology, Cellular Molecular, Clinical-Translational)