Regulation and functional roles of chemokines in liver diseases
Cao S, Liu M, Sehrawat T, Shah V. Regulation and functional roles of chemokines in liver diseases. Nature Reviews Gastroenterology & Hepatology 2021, 18: 630-647. PMID: 33976393, PMCID: PMC9036964, DOI: 10.1038/s41575-021-00444-2.Peer-Reviewed Original ResearchConceptsLiver diseaseImmune cellsAlcohol-associated liver diseaseOngoing clinical trialsRelevant preclinical studiesFunction of chemokinesLiver infiltrationChemokine transcriptionNonalcoholic steatohepatitisChemokine productionCell-type specific productionClinical trialsInflammatory responseFunctional rolePreclinical studiesChemokine functionAnimal modelsChemokinesChemokine biologyLiver homeostasisTherapeutic opportunitiesDiseaseLiver cellsCellsWeight proteinsEpigenetics of alcohol-related liver diseases
Habash N, Sehrawat T, Shah V, Cao S. Epigenetics of alcohol-related liver diseases. JHEP Reports 2022, 4: 100466. PMID: 35462859, PMCID: PMC9018389, DOI: 10.1016/j.jhepr.2022.100466.Peer-Reviewed Original ResearchAlcohol-related liver diseaseLiver diseaseMajor public health problemChronic liver diseasePublic health problemProinflammatory roleSignificant morbidityMultiple disease statesHealth problemsDisease statesDiseaseClinical applicationNon-coding RNADiagnosisEpigenetic alterationsPrimary causeCurrent knowledgeEpigenetic changesReview articleStudy of epigeneticsHepatologistsMorbidityComplicationsChemokinesPathophysiology