2022
Clinically adjudicated deceased donor acute kidney injury and graft outcomes
Mansour SG, Khoury N, Kodali R, Virmani S, Reese PP, Hall IE, Jia Y, Yamamoto Y, Thiessen-Philbrook HR, Obeid W, Doshi MD, Akalin E, Bromberg JS, Harhay MN, Mohan S, Muthukumar T, Singh P, Weng FL, Moledina DG, Greenberg JH, Wilson FP, Parikh CR. Clinically adjudicated deceased donor acute kidney injury and graft outcomes. PLOS ONE 2022, 17: e0264329. PMID: 35239694, PMCID: PMC8893682, DOI: 10.1371/journal.pone.0264329.Peer-Reviewed Original ResearchConceptsDonor Acute Kidney InjuryAcute kidney injuryGraft failureAKI phenotypesKidney injuryUrine biomarkersLack of associationAKI casesGraft functionHigher DGFPotential kidneyGraft outcomeDeceased donorsOrgan utilizationMCP-1YKL-40Donor StudyEGFRDGFAncillary analysisAvailable chartsBiomarkersInjuryPhenotypeAssociation
2017
Kidney Injury and Repair Biomarkers in Marathon Runners
Mansour SG, Verma G, Pata RW, Martin TG, Perazella MA, Parikh CR. Kidney Injury and Repair Biomarkers in Marathon Runners. American Journal Of Kidney Diseases 2017, 70: 252-261. PMID: 28363731, PMCID: PMC5526736, DOI: 10.1053/j.ajkd.2017.01.045.Peer-Reviewed Original ResearchConceptsCreatinine levelsDay 0Kidney injuryTubular injuryUrine albuminSerum creatinineKidney functionUrine biomarkersBiomarker levelsSerum creatine kinase levelsMarathon runnersAKI Network criteriaAKI stage 1Stage 1 AKISerum creatinine levelsRenal tubular epithelial cellsLimited clinical dataCreatine kinase levelsTubular epithelial cellsDL increaseMean ageMicroscopy scoreGranular castsClinical dataObservational studyBiomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review
Mansour SG, Puthumana J, Coca SG, Gentry M, Parikh CR. Biomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review. BMC Nephrology 2017, 18: 72. PMID: 28219345, PMCID: PMC5319065, DOI: 10.1186/s12882-017-0490-0.Peer-Reviewed Original ResearchConceptsMatrix metalloproteinase-2Renal outcomesRenal functionRenal fibrosisStage ISystematic reviewWorse renal outcomeChronic kidney diseaseBiomarkers of fibrosisChemoattractant protein-1Diverse patient populationsGrowth factor βUrine biomarkersKidney diseaseMCP-1Patient populationDisease progressionMetalloproteinase-2FibrosisModerate positive correlationStage IIPatientsUnifying pathwayBiomarkersReliability of blood